Search Results - "Van, Hieu T."

Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1 by Tanaka, Noriaki, Zhao, Mei, Tang, Lin, Patel, Ameeta A., Xi, Qing, Van, Hieu T., Takahashi, Hideaki, Osman, Abdullah A., Zhang, Jiexin, Wang, Jing, Myers, Jeffrey N., Zhou, Ge

“…Many mutant p53 proteins exert oncogenic gain-of-function (GOF) properties that promote cancer cell invasive growth and metastasis, yet the mechanisms…”
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Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer by Caetano, Mauricio S., Hassane, Maya, Van, Hieu T., Bugarin, Emmanuel, Cumpian, Amber M., McDowell, Christina L., Cavazos, Carolina Gonzalez, Zhang, Huiyuan, Deng, Shanshan, Diao, Lixia, Wang, Jing, Evans, Scott E., Behrens, Carmen, Wistuba, Ignacio I., Fuqua, Susan A. W., Lin, Huang, Stabile, Laura P., Watowich, Stephanie S., Kadara, Humam, Moghaddam, Seyed Javad

“…Lung adenocarcinomas (LUADs) with mutations in the K-ras oncogene display dismal prognosis. Proinflammatory and immunomodulatory events that drive development…”
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KMT2 Family of H3K4 Methyltransferases: Enzymatic Activity-dependent and -independent Functions by Van, Hieu T., Xie, Guojia, Dong, Peng, Liu, Zhe, Ge, Kai

“…[Display omitted] •KMT2 methyltransferases are responsible for methylation on H3K4.•KMT2 family include six members: KMT2A/B, KMT2C/D, and KMT2F/G.•KMT2s play…”
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Histone modifications and the DNA double-strand break response by Van, Hieu T., Santos, Margarida A.

“…The timely and precise repair of DNA damage, or more specifically DNA double-strand breaks (DSBs) - the most deleterious DNA lesions, is crucial for…”
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CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas by Veazey, Kylee J., Cheng, Donghang, Lin, Kevin, Villarreal, Oscar D., Gao, Guozhen, Perez-Oquendo, Mabel, Van, Hieu T., Stratton, Sabrina A., Green, Michael, Xu, Han, Lu, Yue, Bedford, Mark T., Santos, Margarida Almeida

“…Somatic mutations affecting CREBBP and EP300 are a hallmark of diffuse large B-cell lymphoma (DLBCL). These mutations are frequently monoallelic, within the…”
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Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression–regulating NSL complexes by Van, Hieu T., Harkins, Peter R., Patel, Avni, Jain, Abhinav K., Lu, Yue, Bedford, Mark T., Santos, Margarida A.

“…The methyl-lysine readers plant homeodomain finger protein 20 (PHF20) and its homolog PHF20-like protein 1 (PHF20L1) are known components of the nonspecific…”
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Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches by Das, Prosun, Veazey, Kylee J., Van, Hieu T., Kaushik, Saakshi, Lin, Kevin, Lu, Yue, Ishii, Masaru, Kikuta, Junichi, Ge, Kai, Nussenzweig, Andre, Santos, Margarida A.

“…The bone is essential for locomotion, calcium storage, and harboring the hematopoietic stem cells (HSCs) that supply the body with mature blood cells…”
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An Alternative Approach to Assess the Impacts of Countercyclical Fiscal Policy in Developing Countries by Van Hieu Nguyen, Thai Hong Le

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