Search Results - "Van't Land, Belinda"

Human milk oligosaccharides promote immune tolerance via direct interactions with human dendritic cells by Xiao, Ling, Worp, Wouter RPH, Stassen, Roderick, Maastrigt, Celine, Kettelarij, Nienke, Stahl, Bernd, Blijenberg, Bernadet, Overbeek, Saskia A., Folkerts, Gert, Garssen, Johan, van't Land, Belinda

“…Human milk oligosaccharides (HMOS) are a complex mixture of bioactive components supporting the immune development of breastfed‐infants. Dendritic cells (DCs)…”
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Pollen exposure weakens innate defense against respiratory viruses by Gilles, Stefanie, Blume, Cornelia, Wimmer, Maria, Damialis, Athanasios, Meulenbroek, Laura, Gökkaya, Mehmet, Bergougnan, Carolin, Eisenbart, Selina, Sundell, Nicklas, Lindh, Magnus, Andersson, Lars‐Magnus, Dahl, Åslög, Chaker, Adam, Kolek, Franziska, Wagner, Sabrina, Neumann, Avidan U., Akdis, Cezmi A., Garssen, Johan, Westin, Johan, Land, Belinda, Davies, Donna E., Traidl‐Hoffmann, Claudia

“…Background Hundreds of plant species release their pollen into the air every year during early spring. During that period, pollen allergic as well as…”
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Deoxynivalenol exposure during pregnancy has adverse effects on placental structure and immunity in mice model by Toutounchi, Negisa Seyed, Braber, Saskia, Land, Belinda van‘t, Thijssen, Suzan, Garssen, Johan, Folkerts, Gert, Hogenkamp, Astrid

“…Deoxynivalenol (DON), a highly prevalent food contaminant, is known to induce reproductive and immunotoxicity in humans upon exposure. The present study…”
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Human Milk Oligosaccharide 2'-Fucosyllactose Improves Innate and Adaptive Immunity in an Influenza-Specific Murine Vaccination Model by Xiao, Ling, Leusink-Muis, Thea, Kettelarij, Nienke, van Ark, Ingrid, Blijenberg, Bernadet, Hesen, Nienke A, Stahl, Bernd, Overbeek, Saskia A, Garssen, Johan, Folkerts, Gert, Van't Land, Belinda

“…Human milk is uniquely suited to provide optimal nutrition and immune protection to infants. Human milk oligosaccharides are structural complex and diverse…”
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Immunometabolic factors in adolescent chronic disease are associated with Th1 skewing of invariant Natural Killer T cells by Ververs, Francesca A., Engelen, Suzanne E., Nuboer, Roos, Vastert, Bas, van der Ent, Cornelis K., van’t Land, Belinda, Garssen, Johan, Monaco, Claudia, Boes, Marianne, Schipper, Henk S.

“…Invariant Natural Killer T (iNKT) cells respond to the ligation of lipid antigen-CD1d complexes via their T-cell receptor and are implicated in various…”
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Human Milk Oligosaccharide 2′-Fucosyllactose Modulates Local Viral Immune Defense by Supporting the Regulatory Functions of Intestinal Epithelial and Immune Cells by Ayechu-Muruzabal, Veronica, Poelmann, Bente, Berends, Alinda J., Kettelarij, Nienke, Garssen, Johan, van’t Land, Belinda, Willemsen, Linette E. M.

“…Human milk contains bioactive components that provide protection against viral infections in early life. In particular, intestinal epithelial cells (IEC) have…”
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Ovalbumin-Induced Epithelial Activation Directs Monocyte-Derived Dendritic Cells to Instruct Type 2 Inflammation in T Cells Which Is Differentially Modulated by 2′-Fucosyllactose and 3-Fucosyllactose by Zuurveld, Marit, Kiliaan, Pien C.J., van Grinsven, Sophie E.L., Folkerts, Gert, Garssen, Johan, van’t Land, Belinda, Willemsen, Linette E.M.

“…Abstract Allergic sensitization starts with epithelial cell activation driving dendritic cells (DCs) to instruct T helper 2 (Th2) cell polarization. Food…”
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Exposure of Intestinal Epithelial Cells to 2'-Fucosyllactose and CpG Enhances Galectin Release and Instructs Dendritic Cells to Drive Th1 and Regulatory-Type Immune Development by Ayechu-Muruzabal, Veronica, Overbeek, Saskia A, Kostadinova, Atanaska I, Stahl, Bernd, Garssen, Johan, Van't Land, Belinda, Willemsen, Linette E M

“…Intestinal epithelial cells (IEC) release immunomodulatory galectins upon exposure to CpG DNA (mimicking bacterial triggers) and short-chain galacto- and…”
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Fusarium Mycotoxins Disrupt the Barrier and Induce IL-6 Release in a Human Placental Epithelium Cell Line by Seyed Toutounchi, Negisa, Hogenkamp, Astrid, Varasteh, Soheil, Van't Land, Belinda, Garssen, Johan, Kraneveld, Aletta D, Folkerts, Gert, Braber, Saskia

“…Deoxynivalenol, T-2 toxin, and zearalenone, major mycotoxins, contaminate human food on a global level. Exposure to these mycotoxins during pregnancy can lead…”
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Early-Life Nutritional Factors and Mucosal Immunity in the Development of Autoimmune Diabetes by Xiao, Ling, Van't Land, Belinda, van de Worp, Wouter R P H, Stahl, Bernd, Folkerts, Gert, Garssen, Johan

“…Type 1 diabetes (T1D) is an immune-mediated disease with a strong genetic basis but might be influenced by non-genetic factors such as microbiome development…”
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Human Milk Oligosaccharide 3'-GL Improves Influenza-Specific Vaccination Responsiveness and Immunity after Deoxynivalenol Exposure in Preclinical Models by Toutounchi, Negisa Seyed, Braber, Saskia, Hogenkamp, Astrid, Varasteh, Soheil, Cai, Yang, Wehkamp, Tjalling, Tims, Sebastian, Leusink-Muis, Thea, van Ark, Ingrid, Wiertsema, Selma, Stahl, Bernd, Kraneveld, Aletta D, Garssen, Johan, Folkerts, Gert, Van't Land, Belinda

“…Deoxynivalenol (DON), a highly prevalent mycotoxin food contaminant, is known to have immunotoxic effects. In the current study, the potential of dietary…”
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Modulation of the Epithelial-Immune Cell Crosstalk and Related Galectin Secretion by DP3-5 Galacto-Oligosaccharides and β-3'Galactosyllactose by Ayechu-Muruzabal, Veronica, van de Kaa, Melanie, Mukherjee, Reshmi, Garssen, Johan, Stahl, Bernd, Pieters, Roland J, Van't Land, Belinda, Kraneveld, Aletta D, Willemsen, Linette E M

“…Prebiotic galacto-oligosaccharides (GOS) were shown to support mucosal immune development by enhancing regulatory-type Th1 immune polarization induced by…”
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Alterations in regulatory T cells induced by specific oligosaccharides improve vaccine responsiveness in mice by Schijf, Marcel A, Kerperien, Joann, Bastiaans, Jacqueline, Szklany, Kirsten, Meerding, Jenny, Hofman, Gerard, Boon, Louis, van Wijk, Femke, Garssen, Johan, Van't Land, Belinda

“…Prophylactic vaccinations are generally performed to protect naïve individuals with or without suppressed immune responsiveness. In a mouse model for Influenza…”
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Combined Exposure of Activated Intestinal Epithelial Cells to Nondigestible Oligosaccharides and CpG-ODN Suppresses Th2-Associated CCL22 Release While Enhancing Galectin-9, TGFβ, and Th1 Polarization by Willemsen, Linette E. M., Garssen, J., van’t land, Belinda, de Jager, Wilco, Hayen, Simone M., Boks, Martine A., Kostadinova, Atanaska I., Overbeek, Saskia A., Knippels, Leon

“…Background. Short-chain galacto- and long-chain fructo-oligosaccharides (scGOS/lcFOS) and CpG-ODN affect intestinal epithelial cells (IEC). Epithelial IL1α may…”
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Exploring Immune Development in Infants With Moderate to Severe Atopic Dermatitis by Hulshof, Lies, Overbeek, Saskia A, Wyllie, Anne L, Chu, Mei Ling J N, Bogaert, Debby, de Jager, Wilco, Knippels, Leon M J, Sanders, Elisabeth A M, van Aalderen, Wim M C, Garssen, Johan, Van't Land, Belinda, Sprikkelman, Aline B

“…Atopic dermatitis (AD) is the most common chronic inflammatory skin disease in infancy with a complex pathology. In adults, the clinical severity of AD has…”
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Regulatory T-cells have a prominent role in the immune modulated vaccine response by specific oligosaccharides by van’t Land, Belinda, Schijf, Marcel, van Esch, Betty C.A.M, van Bergenhenegouwen, Jeroen, Bastiaans, Jacqueline, Schouten, Bastiaan, Boon, Louis, Garssen, Johan

“…Abstract Regulatory T-cells are increasingly important in vaccine strategies. In a Flu-vaccination model the role of CD4+ CD25+ Foxp3+ regulatory T-cells…”
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Altered Host-Microbe Interaction in HIV: A Target for Intervention with Pro- and Prebiotics by Hummelen, Ruben, Vos, Arjan P., Land, Belinda van't, Norren, Klaske van, Reid, Gregor

“…The intestinal immune system is severely affected by HIV and circulating microbial products from the intestinal tract that provide an ongoing source of…”
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Immunomodulation by Human Milk Oligosaccharides: The Potential Role in Prevention of Allergic Diseases by Zuurveld, Marit, van Witzenburg, Nikita P, Garssen, Johan, Folkerts, Gert, Stahl, Bernd, Van't Land, Belinda, Willemsen, Linette E M

“…The prevalence and incidence of allergic diseases is rising and these diseases have become the most common chronic diseases during childhood in Westernized…”
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An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts by Knipping, Karen, Garssen, Johan, van't Land, Belinda

“…Rotaviruses are the single most important cause of severe diarrhea in young children worldwide. The developments of specific, potent and accessible antiviral…”
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Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice by Xiao, Ling, van’t Land, Belinda, Engen, Phillip A., Naqib, Ankur, Green, Stefan J., Nato, Angie, Leusink-Muis, Thea, Garssen, Johan, Keshavarzian, Ali, Stahl, Bernd, Folkerts, Gert

“…Development of Type 1 diabetes (T1D) is influenced by non-genetic factors, such as optimal microbiome development during early life that “programs” the immune…”
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