Search Results - "Valverde, Mahara"

Sustained Activation of TNFα-Induced DNA Damage Response in Newly Differentiated Adipocytes by Valverde, Mahara, Sánchez-Brito, Aarón

“…The response to DNA damage is the mechanism that allows the interaction between stress signals, inflammatory secretions, DNA repair, and maintenance of cell…”
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Interactions between miRNAs and Double-Strand Breaks DNA Repair Genes, Pursuing a Fine-Tuning of Repair by Peraza-Vega, Ricardo I, Valverde, Mahara, Rojas, Emilio

“…The repair of DNA damage is a crucial process for the correct maintenance of genetic information, thus, allowing the proper functioning of cells. Among the…”
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Hydrogen Peroxide-Induced DNA Damage and Repair through the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells by Emilio, Rojas, Rodriguez-Sastre, Maria Alexandra, Fortini, Paola, Lozano-Salgado, Jonathan, Mahara, Valverde, Dogliotti, Eugenia

“…Human adipose-derived mesenchymal stem cells (hADMSCs) are recognized as a potential tool in cell tissue therapy because of their capacity to proliferate and…”
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Post-transcriptional regulation of Rad51c by miR-222 contributes cellular transformation by Rojas, Emilio, Martinez-Pacheco, Monica, Rodriguez-Sastre, Maria Alexandra, Ramos-Espinosa, Paulina, Valverde, Mahara

“…DNA repair inhibition has been described as an essential event leading to the initiation of carcinogenesis. In a previous study, we observed that the exposure…”
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The dual nature of DNA damage response in obesity and bariatric surgery-induced weight loss by Escobar Marcillo, David Israel, Guglielmi, Valeria, Privitera, Grete Francesca, Signore, Michele, Simonelli, Valeria, Manganello, Federico, Dell’Orso, Ambra, Laterza, Serena, Parlanti, Eleonora, Pulvirenti, Alfredo, Marcon, Francesca, Siniscalchi, Ester, Fertitta, Veronica, Iorio, Egidio, Varì, Rosaria, Nisticò, Lorenza, Valverde, Mahara, Sbraccia, Paolo, Dogliotti, Eugenia, Fortini, Paola

“…This novel study applies targeted functional proteomics to examine tissues and cells obtained from a cohort of individuals with severe obesity who underwent…”
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Glutathione depletion triggers actin cytoskeleton changes via actin-binding proteins by Zepeta-Flores, Nahum, Valverde, Mahara, Lopez-Saavedra, Alejandro, Rojas, Emilio

“…The importance of glutathione (GSH) in alternative cellular roles to the canonically proposed, were analyzed in a model unable to synthesize GSH. Gene…”
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As-Cd-Pb Mixture Induces Cellular Transformation via Post-Transcriptional Regulation of Rad51c by miR-222 by Rojas, Emilio, Martínez-Pacheco, Mónica, Rodríguez-Sastre, María Alexandra, Valverde, Mahara

“…Exposure to heavy metals is today a threat to society. The understanding of the molecular processes related to diseases related to exposure to metals mixture…”
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Effect of Air Pollution on the Basal DNA Damage of Mother-Newborn Couples of México City by Valverde, Mahara, Granados, Adriana, Milić, Mirta, Ceppi, Marcello, Sollano, Leticia, Bonassi, Stefano, Rojas, Emilio

“…Environmental pollution of megacities can cause early biological damage such as DNA strand breaks and micronuclei formation. Comet assay tail length (TL)…”
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MicroRNAs Regulate Metabolic Phenotypes During Multicellular Tumor Spheroids Progression by Muciño-Olmos, Erick Andrés, Vázquez-Jiménez, Aarón, López-Esparza, Diana Elena, Maldonado, Vilma, Valverde, Mahara, Resendis-Antonio, Osbaldo

“…During tumor progression, cancer cells rewire their metabolism to face their bioenergetic demands. In recent years, microRNAs (miRNAs) have emerged as…”
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DNA damage and repair assessed by comet assay in workers exposed to lead in a battery recycling by Mahara, Valverde, María, Maldonado, Efraín, Tovar, Emilio, Rojas

“…Abstract only…”
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DNA-AP sites generation by etoposide in whole blood cells by Rojas, Emilio, Mussali, Patricia, Tovar, Efrain, Valverde, Mahara

“…Etoposide is currently one of the most commonly used antitumor drugs. The mechanisms of action proposed for its antitumor activity are based mainly on its…”
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A metal mixture induces transformation upon antioxidant depletion in a hepatic cell line by Sánchez-Valle, Vicente, Valverde, Mahara, Carrizale, Leticia, Mejía, Jesus, Zepeta, Nahum, Rojas, Emilio

“…Metals are ubiquitous soil, air, and water pollutants. A mixture of arsenic cadmium and lead, in particular, has commonly been found in the vicinity of smelter…”
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Measuring DNA modifications with the comet assay: a compendium of protocols by Collins, Andrew, Møller, Peter, Gajski, Goran, Vodenková, Soňa, Abdulwahed, Abdulhadi, Anderson, Diana, Bankoglu, Ezgi Eyluel, Bonassi, Stefano, Boutet-Robinet, Elisa, Brunborg, Gunnar, Chao, Christy, Cooke, Marcus S., Costa, Carla, Costa, Solange, Dhawan, Alok, de Lapuente, Joaquin, Bo’, Cristian Del, Dubus, Julien, Dusinska, Maria, Duthie, Susan J., Yamani, Naouale El, Engelward, Bevin, Gaivão, Isabel, Giovannelli, Lisa, Godschalk, Roger, Guilherme, Sofia, Gutzkow, Kristine B., Habas, Khaled, Hernández, Alba, Herrero, Oscar, Isidori, Marina, Jha, Awadhesh N., Knasmüller, Siegfried, Kooter, Ingeborg M., Koppen, Gudrun, Kruszewski, Marcin, Ladeira, Carina, Laffon, Blanca, Larramendy, Marcelo, Hégarat, Ludovic Le, Lewies, Angélique, Lewinska, Anna, Liwszyc, Guillermo E., de Cerain, Adela López, Manjanatha, Mugimane, Marcos, Ricard, Milić, Mirta, de Andrade, Vanessa Moraes, Moretti, Massimo, Muruzabal, Damian, Novak, Matjaž, Oliveira, Rui, Olsen, Ann-Karin, Owiti, Norah, Pacheco, Mário, Pandey, Alok K., Pfuhler, Stefan, Pourrut, Bertrand, Reisinger, Kerstin, Rojas, Emilio, Rundén-Pran, Elise, Sanz-Serrano, Julen, Shaposhnikov, Sergey, Sipinen, Ville, Smeets, Karen, Stopper, Helga, Teixeira, João Paulo, Valdiglesias, Vanessa, Valverde, Mahara, van Acker, Frederique, van Schooten, Frederik-Jan, Vasquez, Marie, Wentzel, Johannes F., Wnuk, Maciej, Wouters, Annelies, Žegura, Bojana, Zikmund, Tomas, Langie, Sabine A. S., Azqueta, Amaya

“…The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. The types of damage detected encompass…”
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Oxidative stress during courtship affects male and female reproductive effort differentially in a wild bird with biparental care by Montoya, Bibiana, Valverde, Mahara, Rojas, Emilio, Torres, Roxana

“…Oxidative stress has been suggested as one of the physiological mechanisms modulating reproductive effort, including investment in mate choice. Here, we…”
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Cellular and humoral responses to collagen-polyvinylpyrrolidone administered during short and long periods in humans by Furuzawa-Carballeda, Janette, Rojas, Emilio, Valverde, Mahara, Castillo, Irma, Diaz de León, Lino, Krötzsch, Edgar

“…Collagen, particularly type I, and its related derivatives have been extensively employed in many areas of pharmacology. The present study was performed to…”
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Environmental and occupational biomonitoring using the Comet assay by Valverde, Mahara, Rojas, Emilio

“…Biomonitoring of human populations exposed to potential mutagens or carcinogens can provide an early detection system for the initiation of cell disregulation…”
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Causes of genome instability: the effect of low dose chemical exposures in modern society by Langie, Sabine A S, Koppen, Gudrun, Desaulniers, Daniel, Al-Mulla, Fahd, Al-Temaimi, Rabeah, Amedei, Amedeo, Azqueta, Amaya, Bisson, William H, Brown, Dustin G, Brunborg, Gunnar, Charles, Amelia K, Chen, Tao, Colacci, Annamaria, Darroudi, Firouz, Forte, Stefano, Gonzalez, Laetitia, Hamid, Roslida A, Knudsen, Lisbeth E, Leyns, Luc, Lopez de Cerain Salsamendi, Adela, Memeo, Lorenzo, Mondello, Chiara, Mothersill, Carmel, Olsen, Ann-Karin, Pavanello, Sofia, Raju, Jayadev, Rojas, Emilio, Roy, Rabindra, Ryan, Elizabeth P, Ostrosky-Wegman, Patricia, Salem, Hosni K, Scovassi, A Ivana, Singh, Neetu, Vaccari, Monica, Van Schooten, Frederik J, Valverde, Mahara, Woodrick, Jordan, Zhang, Luoping, van Larebeke, Nik, Kirsch-Volders, Micheline, Collins, Andrew R

“…Genome instability is a prerequisite for the development of cancer. It occurs when genome maintenance systems fail to safeguard the genome's integrity, whether…”
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The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders by Milić, Mirta, Ceppi, Marcello, Bruzzone, Marco, Azqueta, Amaya, Brunborg, Gunnar, Godschalk, Roger, Koppen, Gudrun, Langie, Sabine, Møller, Peter, Teixeira, João Paulo, Alija, Avdulla, Anderson, Diana, Andrade, Vanessa, Andreoli, Cristina, Asllani, Fisnik, Bangkoglu, Ezgi Eyluel, Barančoková, Magdalena, Basaran, Nursen, Boutet-Robinet, Elisa, Buschini, Annamaria, Cavallo, Delia, Costa Pereira, Cristiana, Costa, Carla, Costa, Solange, Da Silva, Juliana, Del Boˊ, Cristian, Dimitrijević Srećković, Vesna, Djelić, Ninoslav, Dobrzyńska, Malgorzata, Duračková, Zdenka, Dvořáková, Monika, Gajski, Goran, Galati, Serena, García Lima, Omar, Giovannelli, Lisa, Goroshinskaya, Irina A., Grindel, Annemarie, Gutzkow, Kristine B., Hernández, Alba, Hernández, Carlos, Holven, Kirsten B., Ibero-Baraibar, Idoia, Ottestad, Inger, Kadioglu, Ela, Kažimirová, Alena, Kuznetsova, Elena, Ladeira, Carina, Laffon, Blanca, Lamonaca, Palma, Lebailly, Pierre, Louro, Henriqueta, Mandina Cardoso, Tania, Marcon, Francesca, Marcos, Ricard, Moretti, Massimo, Moretti, Silvia, Najafzadeh, Mojgan, Nemeth, Zsuzsanna, Neri, Monica, Novotna, Bozena, Orlow, Irene, Paduchova, Zuzana, Pastor, Susana, Perdry, Hervé, Spremo-Potparević, Biljana, Ramadhani, Dwi, Riso, Patrizia, Rohr, Paula, Rojas, Emilio, Rossner, Pavel, Safar, Anna, Sardas, Semra, Silva, Maria João, Sirota, Nikolay, Smolkova, Bozena, Staruchova, Marta, Stetina, Rudolf, Stopper, Helga, Surikova, Ekaterina I., Ulven, Stine M., Ursini, Cinzia Lucia, Valdiglesias, Vanessa, Valverde, Mahara, Vodicka, Pavel, Volkovova, Katarina, Wagner, Karl-Heinz, Živković, Lada, Dušinská, Maria, Collins, Andrew R., Bonassi, Stefano

“…•The alkaline comet assay is a popular methods for assessing DNA damage in humans.•A database of 19,320 subjects from 44 laboratories in 26 countries was…”
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DNA Integrity Estimated via the Comet Assay Reflects Oxidative Stress and Competitive Disadvantage in Developing Birds by Montoya, Bibiana, Gil, Diego, Valverde, Mahara, Rojas, Emilio, Pérez-Rodríguez, Lorenzo

“…AbstractIncreases in DNA degradation have been detected in numerous situations in which organisms are exposed to pollutants. However, outside of the…”
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Effects of atmospheric pollutants on the Nrf2 survival pathway by Rubio, Valentina, Valverde, Mahara, Rojas, Emilio

“…Background, aim, and scope Atmospheric pollution is a worldwide problem. Exposure to atmospheric pollutants causes toxic cellular effects. One of the…”
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