Search Results - "Valtonen, Joona"

Coronary artery disease patient-derived iPSC-hepatocytes have distinct miRNA profile that may alter lipid metabolism by Alexanova, Anna, Raitoharju, Emma, Valtonen, Joona, Aalto-Setälä, Katriina, Viiri, Leena E.

“…Metabolic dysfunction, partly driven by altered liver function, predisposes to coronary artery disease (CAD), but the role of liver in vulnerable…”
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The Junctophilin-2 Mutation p.(Thr161Lys) Is Associated with Hypertrophic Cardiomyopathy Using Patient-Specific iPS Cardiomyocytes and Demonstrates Prolonged Action Potential and Increased Arrhythmogenicity by Valtonen, Joona, Prajapati, Chandra, Cherian, Reeja Maria, Vanninen, Sari, Ojala, Marisa, Leivo, Krista, Heliö, Tiina, Koskenvuo, Juha, Aalto-Setälä, Katriina

“…Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases; it is primarily caused by mutations in sarcomeric genes. However, HCM is…”
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Abstract 10925: A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Prolonged Relaxation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes With Hypertrophic Cardiomyopathy by Valtonen, Joona, Aalto-Setala, Katriina

“…Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases primarily caused by mutations in sarcomeric genes. However, HCM is also…”
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The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes by Rantakari, Pia, Auvinen, Kaisa, Jäppinen, Norma, Kapraali, Maria, Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Iftakhar-E-Khuda, Imtiaz, Keuschnigg, Johannes, Umemoto, Eiji, Tohya, Kazuo, Miyasaka, Masayuki, Elima, Kati, Jalkanen, Sirpa, Salmi, Marko

“…PLVAP is a blood vessel endothelium marker of uncertain function. Salmi and colleagues demonstrate that PLVAP is also expressed on lymphoid endothelial cells,…”
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Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury by Rantakari, Pia, Patten, Daniel A., Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Dawes, Harriet, Laurila, Juha, Ohlmeier, Steffen, Elima, Kati, Hübscher, Stefan G., Weston, Chris J., Jalkanen, Sirpa, Adams, David H., Salmi, Marko, Shetty, Shishir

“…Macrophages are key regulators of fibrosis development and resolution. Elucidating the mechanisms by which they mediate this process is crucial for…”
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Gellan gum-gelatin based cardiac models support formation of cellular networks and functional cardiomyocytes by Vuorenpää, Hanna, Valtonen, Joona, Penttinen, Kirsi, Koskimäki, Sanna, Hovinen, Emma, Ahola, Antti, Gering, Christine, Parraga, Jenny, Kelloniemi, Minna, Hyttinen, Jari, Kellomäki, Minna, Aalto-Setälä, Katriina, Miettinen, Susanna, Pekkanen-Mattila, Mari

“…Cardiovascular diseases remain as the most common cause of death worldwide. To reveal the underlying mechanisms in varying cardiovascular diseases, in vitro…”
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Aeroallergen challenge promotes dendritic cell proliferation in the airways by Veres, Tibor Z, Voedisch, Sabrina, Spies, Emma, Valtonen, Joona, Prenzler, Frauke, Braun, Armin

“…Aeroallergen provocation induces the rapid accumulation of CD11c(+)MHC class II (MHC II)(+) dendritic cells (DCs) in the lungs, which is driven by an increased…”
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Erratum: The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes by Rantakari, Pia, Auvinen, Kaisa, Jäppinen, Norma, Kapraali, Maria, Valtonen, Joona, Karikoski, Marika, Gerke, Heidi, Iftakhar-E-Khuda, Imtiaz, Keuschnigg, Johannes, Umemoto, Eiji, Tohya, Kazuo, Miyasaka, Masayuki, Elima, Kati, Jalkanen, Sirpa, Salmi, Marko

“…Nat. Immunol. 16, 386–396 (2015); published online 9 February 2015; corrected after print 20 March 2015 In the version of this article initially published, the…”
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