Search Results - "Valtieri, M."
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1
A microRNA code for prostate cancer metastasis
Published in Oncogene (03-03-2016)“…Although the development of bone metastasis is a major detrimental event in prostate cancer, the molecular mechanisms responsible for bone homing and…”
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2
KDR Receptor: A Key Marker Defining Hematopoietic Stem Cells
Published in Science (American Association for the Advancement of Science) (03-09-1999)“…Studies on pluripotent hematopoietic stem cells (HSCs) have been hindered by lack of a positive marker, comparable to the CD34 marker of hematopoietic…”
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3
Multi-level effects of flt3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors
Published in Blood (01-09-1995)“…We have evaluated the effects of the flt3 receptor ligand (FL) on hematopoietic progenitors/stem cells (HPCs/HSCs) stringently purified from adult peripheral…”
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4
PML/RARα fusion protein expression in normal human hematopoietic progenitors dictates myeloid commitment and the promyelocytic phenotype
Published in Blood (15-08-2000)“…The role of fusion proteins in acute myeloid leukemia (AML) is well recognized, but the leukemic target cell and the cellular mechanisms generating the AML…”
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5
Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis
Published in The Journal of clinical investigation (01-05-1995)“…We have explored the expression of the transcription factors GATA-1, GATA-2, and NF-E2 in purified early hematopoietic progenitor cells (HPCs) induced to…”
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6
Key Functional Role and Lineage-Specific Expression of Selected HOXB Genes in Purified Hematopoietic Progenitor Differentiation
Published in Blood (01-12-1994)“…Although it is well established that homeobox (HOX) genes play a key role in normal human embryogenesis, the expression and function of HOX genes in normal…”
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7
Expression of Growth Factor Receptors in Unilineage Differentiation Culture of Purified Hematopoietic Progenitors
Published in Blood (01-11-1996)“…We have evaluated the expression of growth factor receptors (GFRs) on early hematopoietic progenitor cells (HPCs) purified from human adult peripheral blood…”
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8
T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice
Published in Cancer research (Chicago, Ill.) (15-11-1996)“…The TAL-1 gene specifies for a basic domain-helix-loop-helix protein, which is involved in the control of normal hematopoiesis. In human pathology, the TAL-1…”
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9
Cytokine-dependent granulocytic differentiation. Regulation of proliferative and differentiative responses in a murine progenitor cell line
Published in The Journal of immunology (1950) (01-06-1987)“…Human granulocyte colony stimulating factor (G-CSF) can support the survival and short term proliferation of the interleukin 3 (IL 3)-dependent diploid murine…”
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10
In Vitro Human Immunodeficiency Virus-1 Infection of Purified Hematopoietic Progenitors in Single-Cell Culture
Published in Blood (01-03-1995)“…Uni- or multi-lineage suppression of hematopoiesis is observed in the majority of acquired immunodeficiency syndrome (AIDS) patients. The mechanism(s)…”
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11
Cell Cycle-Dependent Initiation and Lineage-Dependent Abrogation of GATA-1 Expression in Pure Differentiating Hematopoietic Progenitors
Published in Proceedings of the National Academy of Sciences - PNAS (15-07-1992)“…The programmed activation/repression of transcription factors in early hematopoietic differentiation has not yet been explored. The DNA-binding protein GATA-1…”
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12
Ectopic expression of interferon regulatory factor-1 potentiates granulocytic differentiation
Published in Biochemical journal (01-12-2001)“…Numerous transcription factors allow haematopoietic cells to respond to lineage- and stage-specific cytokines and to act as their effectors. It is increasingly…”
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13
Normal and Leukemic Hematopoietic Cells Manifest Differential Sensitivity to Inhibitory Effects of c-myb Antisense Oligodeoxynucleotides: An in vitro Study Relevant to Bone Marrow Purging
Published in Proceedings of the National Academy of Sciences - PNAS (15-03-1991)“…The c-myb protooncogene is preferentially expressed in hematopoietic cells, and its encoded protein, Myb, is required for hematopoietic cell proliferation. To…”
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14
Expression and role of PML gene in normal adult hematopoiesis : functional interaction between PML and Rb proteins in erythropoiesis
Published in Oncogene (10-06-1999)“…The expression of the PML gene was investigated in purified early hematopoietic progenitor cells (HPCs) induced to unilineage erythroid or granulocytic…”
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15
Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade
Published in Molecular and Cellular Biology (01-05-1997)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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16
Enforced TAL-1 expression stimulates primitive, erythroid, and megakaryocytic progenitors but blocks the granulopoietic differentiation program
Published in Cancer research (Chicago, Ill.) (01-02-1998)“…In human adult hematopoiesis, the TAL-1 gene is up- and down-modulated in erythropoiesis and granulopoiesis, respectively [G. L. Condorelli et al., Blood, 86:…”
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17
Transforming growth factor-beta potentiates vitamin D3-induced terminal monocytic differentiation of human leukemic cell lines
Published in The Journal of immunology (1950) (15-03-1993)“…We have investigated the effects of 1,25-dihydroxyvitamin D3 (D3) and/or transforming growth factor (TGF)-beta on one monocytic (U-937) and two human…”
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18
Modulation of Retinoblastoma Gene in Normal Adult Hematopoiesis: Peak Expression and Functional Role in Advanced Erythroid Differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (23-05-1995)“…The retinoblastoma (RB) gene specifies a nuclear phosphoprotein (pRb 105), which is a prototype tumor suppressor inactivated in a variety of human tumors…”
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19
Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines
Published in Blood (01-07-1987)“…Eight permanent cell lines were established from cells of 50 consecutive patients with childhood acute leukemia. Three cell lines required growth…”
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20
Retinoic acid downmodulates erythroid differentiation and GATA1 expression in purified adult-progenitor culture
Published in Blood (01-02-1994)“…All-trans retinoic acid (RA) is an important morphogen in vertebrate development, a normal constituent in human adult blood and is also involved in the control…”
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