Search Results - "Valta, Milla"

Distinct cellular immune responses in children en route to type 1 diabetes with different first-appearing autoantibodies by Starskaia, Inna, Valta, Milla, Pietilä, Sami, Suomi, Tomi, Pahkuri, Sirpa, Kalim, Ubaid Ullah, Rasool, Omid, Rydgren, Emilie, Hyöty, Heikki, Knip, Mikael, Veijola, Riitta, Ilonen, Jorma, Toppari, Jorma, Lempainen, Johanna, Elo, Laura L., Lahesmaa, Riitta

“…Previous studies have revealed heterogeneity in the progression to clinical type 1 diabetes in children who develop islet-specific antibodies either to insulin…”
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Non-HLA Gene Polymorphisms in the Pathogenesis of Type 1 Diabetes: Phase and Endotype Specific Effects by Laine, Antti-Pekka, Valta, Milla, Toppari, Jorma, Knip, Mikael, Veijola, Riitta, Ilonen, Jorma, Lempainen, Johanna

“…The non-HLA loci conferring susceptibility to type 1 diabetes determine approximately half of the genetic disease risk, and several of them have been shown to…”
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CXADR polymorphism rs6517774 modifies islet autoimmunity characteristics and exhibits sex disparity by Nygård, Lucas, Valta, Milla, Laine, Antti-Pekka, Toppari, Jorma, Knip, Mikael, Veijola, Riitta, Hyöty, Heikki, Ilonen, Jorma, Lempainen, Johanna

“…Enteroviral infections have been linked to the development of islet autoimmunity (IA) and type 1 diabetes (T1D), and the coxsackie and adenovirus receptor…”
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Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells by Valta, Milla, Gazali, Ahmad Mahfuz, Viisanen, Tyyne, Ihantola, Emmi‐Leena, Ekman, Ilse, Toppari, Jorma, Knip, Mikael, Veijola, Riitta, Ilonen, Jorma, Lempainen, Johanna, Kinnunen, Tuure

“…Dysfunction of FOXP3‐positive regulatory T cells (Tregs) likely plays a major role in the pathogenesis of multiple autoimmune diseases including type 1…”
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The effect of type 1 diabetes protection and susceptibility associated HLA class II genotypes on DNA methylation in immune cells by Pahkuri, Sirpa, Katayama, Shintaro, Valta, Milla, Nygård, Lucas, Knip, Mikael, Kere, Juha, Ilonen, Jorma, Lempainen, Johanna

“…The HLA region, especially HLA class I and II genes, which encode molecules for antigen presentation to T cells, plays a major role in the predisposition to…”
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Viral infection‐related gene upregulation in monocytes in children with signs of β‐cell autoimmunity by Valta, Milla, Yoshihara, Masahito, Einarsdottir, Elisabet, Pahkuri, Sirpa, Ezer, Sini, Katayama, Shintaro, Knip, Mikael, Veijola, Riitta, Toppari, Jorma, Ilonen, Jorma, Kere, Juha, Lempainen, Johanna

“…Objective The pathogenesis of type 1 diabetes (T1D) is associated with genetic predisposition and immunological changes during presymptomatic disease…”
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