Search Results - "Valsoni, Sara"

SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome by Sebestyén, Endre, Marullo, Fabrizia, Lucini, Federica, Petrini, Cristiano, Bianchi, Andrea, Valsoni, Sara, Olivieri, Ilaria, Antonelli, Laura, Gregoretti, Francesco, Oliva, Gennaro, Ferrari, Francesco, Lanzuolo, Chiara

“…Hutchinson-Gilford progeria syndrome is a genetic disease caused by an aberrant form of Lamin A resulting in chromatin structure disruption, in particular by…”
Get full text

Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells by Luff, Stephanie A., Creamer, J. Philip, Valsoni, Sara, Dege, Carissa, Scarfò, Rebecca, Dacunto, Analisa, Cascione, Sara, Randolph, Lauren N., Cavalca, Eleonora, Merelli, Ivan, Morris, Samantha A., Ditadi, Andrea, Sturgeon, Christopher M.

“…The generation of haematopoietic stem cells (HSCs) from human pluripotent stem cells (hPSCs) is a major goal for regenerative medicine. During embryonic…”
Get full text

Skeletal muscle characteristics are preserved in hTERT/cdk4 human myogenic cell lines by Thorley, Matthew, Duguez, Stéphanie, Mazza, Emilia Maria Cristina, Valsoni, Sara, Bigot, Anne, Mamchaoui, Kamel, Harmon, Brennan, Voit, Thomas, Mouly, Vincent, Duddy, William

“…hTERT/cdk4 immortalized myogenic human cell lines represent an important tool for skeletal muscle research, being used as therapeutically pertinent models of…”
Get full text

Durable and efficient gene silencing in vivo by hit-and-run epigenome editing by Cappelluti, Martino Alfredo, Mollica Poeta, Valeria, Valsoni, Sara, Quarato, Piergiuseppe, Merlin, Simone, Merelli, Ivan, Lombardo, Angelo

“…Permanent epigenetic silencing using programmable editors equipped with transcriptional repressors holds great promise for the treatment of human diseases 1 –…”
Get full text

Dysfunctional polycomb transcriptional repression contributes to lamin A/C-dependent muscular dystrophy by Bianchi, Andrea, Mozzetta, Chiara, Pegoli, Gloria, Lucini, Federica, Valsoni, Sara, Rosti, Valentina, Petrini, Cristiano, Cortesi, Alice, Gregoretti, Francesco, Antonelli, Laura, Oliva, Gennaro, De Bardi, Marco, Rizzi, Roberto, Bodega, Beatrice, Pasini, Diego, Ferrari, Francesco, Bearzi, Claudia, Lanzuolo, Chiara

“…Lamin A is a component of the inner nuclear membrane that, together with epigenetic factors, organizes the genome in higher order structures required for…”
Get full text

DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes by Giordano, Anna Maria Sole, Luciani, Marco, Gatto, Francesca, Abou Alezz, Monah, Beghè, Chiara, Della Volpe, Lucrezia, Migliara, Alessandro, Valsoni, Sara, Genua, Marco, Dzieciatkowska, Monika, Frati, Giacomo, Tahraoui-Bories, Julie, Giliani, Silvia Clara, Orcesi, Simona, Fazzi, Elisa, Ostuni, Renato, D'Alessandro, Angelo, Di Micco, Raffaella, Merelli, Ivan, Lombardo, Angelo, Reijns, Martin A M, Gromak, Natalia, Gritti, Angela, Kajaste-Rudnitski, Anna

“…Aberrant induction of type I IFN is a hallmark of the inherited encephalopathy Aicardi-Goutières syndrome (AGS), but the mechanisms triggering disease in the…”
Get full text

Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence by Ganci, Federica, Sacconi, Andrea, Manciocco, Valentina, Covello, Renato, Benevolo, Maria, Rollo, Francesca, Strano, Sabrina, Valsoni, Sara, Bicciato, Silvio, Spriano, Giuseppe, Muti, Paola, Fontemaggi, Giulia, Blandino, Giovanni

“…Head and neck squamous cell carcinoma is typically characterized by a high incidence of local recurrences. It has been extensively shown that mucosa from head…”
Get full text

PI3K Inhibitors Curtail MYC-Dependent Mutant p53 Gain-of-Function in Head and Neck Squamous Cell Carcinoma by Ganci, Federica, Pulito, Claudio, Valsoni, Sara, Sacconi, Andrea, Turco, Chiara, Vahabi, Mahrou, Manciocco, Valentina, Mazza, Emilia Maria Cristina, Meens, Jalna, Karamboulas, Christina, Nichols, Anthony C, Covello, Renato, Pellini, Raul, Spriano, Giuseppe, Sanguineti, Giuseppe, Muti, Paola, Bicciato, Silvio, Ailles, Laurie, Strano, Sabrina, Fontemaggi, Giulia, Blandino, Giovanni

“…Mutation of gene is a hallmark of head and neck squamous cell carcinoma (HNSCC) not yet exploited therapeutically. mutation frequently leads to the synthesis…”
Get full text

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing by Migliara, Alessandro, Cappelluti, Martino Alfredo, Giannese, Francesca, Valsoni, Sara, Coglot, Alberto, Merelli, Ivan, Cittaro, Davide, Lombardo, Angelo

“…Gene inactivation is instrumental to study gene function and represents a promising strategy for the treatment of a broad range of diseases. Among traditional…”
Get more information

CD32 captures committed haemogenic endothelial cells during human embryonic development by Scarfò, Rebecca, Randolph, Lauren N., Abou Alezz, Monah, El Khoury, Mahassen, Gersch, Amélie, Li, Zhong-Yin, Luff, Stephanie A., Tavosanis, Andrea, Ferrari Ramondo, Giulia, Valsoni, Sara, Cascione, Sara, Didelon, Emma, Passerini, Laura, Amodio, Giada, Brandas, Chiara, Villa, Anna, Gregori, Silvia, Merelli, Ivan, Freund, Jean-Noël, Sturgeon, Christopher M., Tavian, Manuela, Ditadi, Andrea

“…During embryonic development, blood cells emerge from specialized endothelial cells, named haemogenic endothelial cells (HECs). As HECs are rare and only…”
Get full text

Identification of a retinoic acid-dependent hemogenic endothelial progenitor from human pluripotent stem cells by Luff, Stephanie A., Creamer, J. Philip, Valsoni, Sara, Dege, Carissa, Scarfò, Rebecca, Dacunto, Analisa, Cascione, Sara, Randolph, Lauren N., Cavalca, Eleonora, Merelli, Ivan, Morris, Samantha, Ditadi, Andrea, Sturgeon, Christopher M.

Get full text

A bioinformatics pipeline to uncover regulatory modules and their condition-specific regulators in human monocyte-to-macrophages differentiation and polarization by Emilia Maria Cristina, Mazza, Paola, Italiani, Sara, Valsoni, Ingrid, Cifola, Diana, Boraschi, Cristina, Battaglia, Silvio, Bicciato

“…Abstract only…”
Get full text