Search Results - "Vallon, V"

Cardiovascular benefits of SGLT2 inhibition in diabetes and chronic kidney diseases by Layton, A. T., Vallon, V.

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The role of the BK channel in potassium homeostasis and flow-induced renal potassium excretion by Rieg, T., Vallon, V., Sausbier, M., Sausbier, U., Kaissling, B., Ruth, P., Osswald, H.

“…The kidney is the major regulator of potassium homeostasis. In addition to the ROMK channels, large conductance Ca2+-activated K+ (BK) channels are expressed…”
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P2Y2 receptor activation inhibits the expression of the sodium-chloride cotransporter NCC in distal convoluted tubule cells by Gailly, P., Szutkowska, M., Olinger, E., Debaix, H., Seghers, F., Janas, S., Vallon, V., Devuyst, O.

“…Luminal nucleotide stimulation is known to reduce Na + transport in the distal nephron. Previous studies suggest that this mechanism may involve the…”
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Primary kidney growth and its consequences at the onset of diabetes mellitus by Satriano, J, Vallon, V

“…Diabetes mellitus is a primary contributor to progressive kidney dysfunction leading to end-stage renal disease (ESRD). In the early phase of diabetes, prior…”
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Luminal hypotonicity in proximal tubules of aquaporin-1-knockout mice by Vallon, V, Verkman, A S, Schnermann, J

“…To examine the role of aquaporin-1 (AQP1) in near-isosmolar fluid reabsorption in the proximal tubule, we compared osmolalities in micropuncture samples of…”
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Tubuloglomerular feedback responses of the downstream efferent resistance: Unmasking a role for adenosine? by Blantz, R.C., Vallon, V.

“…This Commentary aims to integrate or interrelate the available in vivo data with the in vitro study by Ren and co-workers, which comes to the somewhat…”
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Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia by Rieg, T, Richter, K, Osswald, H, Vallon, V

“…Mice that lack or over-express a gene of interest are important tools for unraveling gene function. The determination of single nephron function by…”
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Functional consequences at the single-nephron level of the lack of adenosine A1 receptors and tubuloglomerular feedback in mice by Vallon, V., Richter, K., Huang, D. Y., Rieg, T., Schnermann, J.

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Agmatine, a bioactive metabolite of arginine. Production, degradation, and functional effects in the kidney of the rat by Lortie, M J, Novotny, W F, Peterson, O W, Vallon, V, Malvey, K, Mendonca, M, Satriano, J, Insel, P, Thomson, S C, Blantz, R C

“…Until recently, conversion of arginine to agmatine by arginine decarboxylase (ADC) was considered important only in plants and bacteria. In the following, we…”
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Cardiovascular benefits of SGLT 2 inhibition in diabetes and chronic kidney diseases by Layton, A. T., Vallon, V.

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Homeostatic efficiency of tubuloglomerular feedback is reduced in established diabetes mellitus in rats by Vallon, V, Blantz, R C, Thomson, S

“…We tested the hypothesis that the ability of the tubuloglomerular feedback (TGF) to stabilize renal function is impaired in rats with 7-8 wk of insulin-treated…”
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Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1 by Lang, F, Vallon, V, Grahammer, F, Palmada, M, Böhmer, C

“…The serum- and glucocorticoid-inducible kinase SGK1 is an ubiquitously expressed kinase with the ability to regulate a variety of transport systems. Recent…”
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Inhibition of local nitric oxide synthase increases homeostatic efficiency of tubuloglomerular feedback by Vallon, V, Thomson, S

“…Nephron filtration rate (SNGFR) and proximal tubular reabsorption are coordinated by the processes of tubuloglomerular feedback (TGF) and glomerulotubular…”
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Resetting protects efficiency of tubuloglomerular feedback by Thomson, Scott C., Vallon, Volker, Blantz, Roland C.

“…Resetting protects efficiency of tubuloglomerular feedback. Tubuloglomerular feedback (TGF) may effect long-term protection of total body salt and water or may…”
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Increased tubular flow induces resetting of tubuloglomerular feedback in euvolemic rats by Thomson, S C, Blantz, R C, Vallon, V

“…As single-nephron glomerular filtration rate (SNGFR) and late proximal flow (VLP) increase during growth or following volume expansion, the tubuloglomerular…”
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Acute renal response to the non-peptide vasopressin V2-receptor antagonist SR 121463B in anesthetized rats by Huang, D Y, Pfaff, I, Serradeil-Le Gal, C, Vallon, V

“…Vasopressin V2-receptor antagonists are promising agents for the use in water-retaining diseases. Potential renal mechanisms of action include effects on water…”
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The salt paradox of the early diabetic kidney is independent of renal innervation by Birk, C, Richter, K, Huang, D Y, Piesch, C, Luippold, G, Vallon, V

“…Glomerular filtration rate (GFR) is inversely and thus paradoxically related to dietary NaCl intake in rats and patients with early type 1 diabetes mellitus…”
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Asymmetry of tubuloglomerular feedback effector mechanism with respect to ambient tubular flow by Thomson, S, Vallon, V, Blantz, R C

“…The contribution of preglomerular resistance changes to the tubuloglomerular feedback (TGF) effector response was evaluated by micropuncture in hydropenic…”
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Multiple organic anion transporters contribute to net renal excretion of uric acid by Eraly, Satish A, Vallon, Volker, Rieg, Timo, Gangoiti, Jon A, Wikoff, William R, Siuzdak, Gary, Barshop, Bruce A, Nigam, Sanjay K

“…1 Department of Medicine, University of California, San Diego 2 Department of Pharmacology, University of California, San Diego 4 Department of Pediatrics,…”
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Luminal signal in tubuloglomerular feedback: What about potassium? by Vallon, Volker, Osswald, Hartmut, Blantz, Roland C., Thomson, Scott

“…Luminal signal in tubuloglomerular feedback: What about potassium? Evidence suggests that a minimal luminal [K+] is required to elicit a full tubuloglomerular…”
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