Search Results - "Vallespinos, Mireia"

Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance by D’Errico, Gabriele, Alonso-Nocelo, Marta, Vallespinos, Mireia, Hermann, Patrick C., Alcalá, Sonia, García, Coral Pedrero, Martin-Hijano, Laura, Valle, Sandra, Earl, Julie, Cassiano, Chiara, Lombardia, Luis, Feliu, Jaime, Monti, Maria Chiara, Seufferlein, Thomas, García-Bermejo, Laura, Martinelli, Paola, Carrato, Alfredo, Sainz, Bruno

“…Pancreatic ductal adenocarcinoma (PDAC) is an inherently chemoresistant tumor. Chemotherapy leads to apoptosis of cancer cells, and in previous studies we have…”
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The miR-25-93-106b cluster regulates tumor metastasis and immune evasion via modulation of CXCL12 and PD-L1 by Cioffi, Michele, Trabulo, Sara M, Vallespinos, Mireia, Raj, Deepak, Kheir, Tony Bou, Lin, Meng-Lay, Begum, Julfa, Baker, Ann-Marie, Amgheib, Ala, Saif, Jaimy, Perez, Manuel, Soriano, Joaquim, Desco, Manuel, Gomez-Gaviro, Maria Victoria, Cusso, Lorena, Megias, Diego, Aicher, Alexandra, Heeschen, Christopher

“…The stromal microenvironment controls response to injury and inflammation, and is also an important determinant of cancer cell behavior. However, our…”
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B Lymphocyte commitment program is driven by the proto-oncogene c-Myc by Vallespinós, Mireia, Fernández, David, Rodríguez, Lorena, Alvaro-Blanco, Josué, Baena, Esther, Ortiz, Maitane, Dukovska, Daniela, Martínez, Dolores, Rojas, Ana, Campanero, Miguel R, Moreno de Alborán, Ignacio

“…c-Myc, a member of the Myc family of transcription factors, is involved in numerous biological functions including the regulation of cell proliferation,…”
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c-Myc Regulates Cell Size and Ploidy but Is Not Essential for Postnatal Proliferation in Liver by Baena, Esther, Gandarillas, Alberto, Vallespinós, Mireia, Zanet, Jennifer, Bachs, Oriol, Redondo, Clara, Fabregat, Isabel, Carlos Martinez-A., de Alborán, Ignacio Moreno, Alt, Frederick W.

“…The c-Myc protein is a transcription factor implicated in the regulation of multiple biological processes, including cell proliferation, cell growth, and…”
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MiR-93 Controls Adiposity via Inhibition of Sirt7 and Tbx3 by Cioffi, Michele, Vallespinos-Serrano, Mireia, Trabulo, Sara M., Fernandez-Marcos, Pablo Jose, Firment, Ashley N., Vazquez, Berta N., Vieira, Catarina R., Mulero, Francesca, Camara, Juan A., Cronin, Ultan P., Perez, Manuel, Soriano, Joaquim, G. Galvez, Beatriz, Castells-Garcia, Alvaro, Haage, Verena, Raj, Deepak, Megias, Diego, Hahn, Stephan, Serrano, Lourdes, Moon, Anne, Aicher, Alexandra, Heeschen, Christopher

“…Conquering obesity has become a major socioeconomic challenge. Here, we show that reduced expression of the miR-25-93-106b cluster, or miR-93 alone, increases…”
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Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors by Djurec, Magdolna, Graña, Osvaldo, Lee, Albert, Troulé, Kevin, Espinet, Elisa, Cabras, Lavinia, Navas, Carolina, Blasco, María Teresa, Martín-Díaz, Laura, Burdiel, Miranda, Li, Jing, Liu, Zhaoqi, Vallespinós, Mireia, Sanchez-Bueno, Francisco, Sprick, Martin R., Trumpp, Andreas, Sainz, Bruno, Al-Shahrour, Fátima, Rabadan, Raul, Guerra, Carmen, Barbacid, Mariano

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of abundant desmoplastic stroma primarily composed of cancer-associated fibroblasts…”
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Cancer Stem Cells and Macrophages: Implications in Tumor Biology and Therapeutic Strategies by Machado, Heather L., Vallespinós, Mireia, Carron, Emily, Sainz, Bruno

“…Cancer stem cells (CSCs) are a unique subset of cells within tumors with stemlike properties that have been proposed to be key drivers of tumor initiation and…”
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The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells by López-Gil, Juan Carlos, García-Silva, Susana, Ruiz-Cañas, Laura, Navarro, Diego, Palencia-Campos, Adrián, Giráldez-Trujillo, Antonio, Earl, Julie, Dorado, Jorge, Gómez-López, Gonzalo, Monfort-Vengut, Ana, Alcalá, Sonia, Gaida, Matthias M, García-Mulero, Sandra, Cabezas-Sáinz, Pablo, Batres-Ramos, Sandra, Barreto, Emma, Sánchez-Tomero, Patricia, Vallespinós, Mireia, Ambler, Leah, Lin, Meng-Lay, Aicher, Alexandra, García García de Paredes, Ana, de la Pinta, Carolina, Sanjuanbenito, Alfonso, Ruz-Caracuel, Ignacio, Rodríguez-Garrote, Mercedes, Guerra, Carmen, Carrato, Alfredo, de Cárcer, Guillermo, Sánchez, Laura, Nombela-Arrieta, César, Espinet, Elisa, Sanchez-Arevalo Lobo, Víctor Javier, Heeschen, Christopher, Sainz, Jr, Bruno

“…Pancreatic ductal adenocarcinoma (PDAC) has limited therapeutic options, particularly with immune checkpoint inhibitors. Highly chemoresistant 'stem-like'…”
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Abstract 1724: Pancreatic cancer stem cell metastasis and mitochondrial respiration is dependent on the the ISG15-mediated ubiquitin-like modification process known as ISGylation by Sainz, Bruno, Alcala Sanchez, Sonia, Vallespinos, Mireia

“…Abstract We recently discovered that CSCs of distinct solid tumors (e.g. pancreatic, colon, and liver) contain intracellular vesicles coated in the…”
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Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma by Alonso-Nocelo, Marta, Ruiz-Cañas, Laura, Sancho, Patricia, Görgülü, Kıvanç, Alcalá, Sonia, Pedrero, Coral, Vallespinos, Mireia, López-Gil, Juan Carlos, Ochando, Marina, García-García, Elena, David Trabulo, Sara Maria, Martinelli, Paola, Sánchez-Tomero, Patricia, Sánchez-Palomo, Carmen, Gonzalez-Santamaría, Patricia, Yuste, Lourdes, Wörmann, Sonja Maria, Kabacaoğlu, Derya, Earl, Julie, Martin, Alberto, Salvador, Fernando, Valle, Sandra, Martin-Hijano, Laura, Carrato, Alfredo, Erkan, Mert, García-Bermejo, Laura, Hermann, Patrick C, Algül, Hana, Moreno-Bueno, Gema, Heeschen, Christopher, Portillo, Francisco, Cano, Amparo, Sainz, , Jr, Bruno

“…The lysyl oxidase-like protein 2 (LOXL2) contributes to tumour progression and metastasis in different tumour entities, but its role in pancreatic ductal…”
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Tumor-associated macrophage-secreted 14-3-3[zeta] signals via AXL to promote pancreatic cancer chemoresistance by D'Errico, Gabriele, Alonso-Nocelo, Marta, Vallespinos, Mireia, Hermann, Patrick C, Alcalá, Sonia, García, Coral Pedrero, Ma

“…Pancreatic ductal adenocarcinoma (PDAC) is an inherently chemoresistant tumor. Chemotherapy leads to apoptosis of cancer cells, and in previous studies we have…”
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Abstract 5667: Exposure of tumor-associated macrophages to apoptotic pancreatic cancer cells promotes cancer stem cell chemoresistance by D'Errico, Gabriele, Vallespinos, Mireia, Alcala, Sonia, Valle, Sandra, Martin-Hijano, Laura, Sainz, Bruno

“…Abstract Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer related deaths worldwide. This is largely due to the existence of a…”
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Bcl3 Couples Cancer Stem Cell Enrichment With Pancreatic Cancer Molecular Subtypes by Ai, Jiaoyu, Wörmann, Sonja M., Görgülü, Kıvanç, Vallespinos, Mireia, Zagorac, Sladjana, Alcala, Sonia, Wu, Nan, Kabacaoglu, Derya, Berninger, Alexandra, Navarro, Diego, Kaya-Aksoy, Ezgi, Ruess, Dietrich A., Ciecielski, Katrin J., Kowalska, Marlena, Demir, Ihsan Ekin, Ceyhan, Güralp O., Heid, Irina, Braren, Rickmer, Riemann, Marc, Schreiner, Sabrina, Hofmann, Samuel, Kutschke, Maria, Jastroch, Martin, Slotta-Huspenina, Julia, Muckenhuber, Alexander, Schlitter, Anna Melissa, Schmid, Roland M., Steiger, Katja, Diakopoulos, Kalliope N., Lesina, Marina, Sainz, Bruno, Algül, Hana

“…The existence of different subtypes of pancreatic ductal adenocarcinoma (PDAC) and their correlation with patient outcome have shifted the emphasis on patient…”
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Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy by Alcalá, Sonia, Villarino, Lara, Ruiz-Cañas, Laura, Couceiro, José R, Martínez-Calvo, Miguel, Palencia-Campos, Adrián, Navarro, Diego, Cabezas-Sainz, Pablo, Rodriguez-Arabaolaza, Iker, Cordero-Barreal, Alfonso, Trilla-Fuertes, Lucia, Rubiolo, Juan A, Batres-Ramos, Sandra, Vallespinos, Mireia, González-Páramos, Cristina, Rodríguez, Jéssica, Gámez-Pozo, Angelo, Vara, Juan Ángel Fresno, Fernández, Sara Fra, Berlinches, Amparo Benito, Moreno-Mata, Nicolás, Redondo, Ana María Torres, Carrato, Alfredo, Hermann, Patrick C, Sánchez, Laura, Torrente, Susana, Fernández-Moreno, Miguel Ángel, Mascareñas, José L, Sainz, Jr, Bruno

“…Previous studies by our group have shown that oxidative phosphorylation (OXPHOS) is the main pathway by which pancreatic cancer stem cells (CSCs) meet their…”
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Bcl-3 regulates cancer stem cell-ness and metastatic properties in pancreatic ductal adenocarcinoma by Ai, Jiaoyu, Wörmann, Sonja, Vallespinos, Mireia, Görgülü, Kivanc, Diakopoulos, Kalliope, Steiger, Katja, Riemann, Marc, Lesina, Marina, Sainz, Bruno, Algül, Hana

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