Search Results - "Vallejo, Antonio J"
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Improving the Detection of Potential Cases of Familial Hypercholesterolemia: Could Machine Learning Be Part of the Solution?
Published in Journal of the American Heart Association (15-06-2024)“…Familial hypercholesterolemia (FH), while highly prevalent, is a significantly underdiagnosed monogenic disorder. Improved detection could reduce the large…”
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Triglyceride-Rich Lipoprotein Cholesterol and Risk of Cardiovascular Events Among Patients Receiving Statin Therapy in the TNT Trial
Published in Circulation (New York, N.Y.) (21-08-2018)“…BACKGROUND:Mendelian randomization data suggest that the genetic determinants of lifetime higher triglyceride-rich lipoprotein-cholesterol (TRL-C) are causally…”
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Epidemiology of familial hypercholesterolaemia: Community and clinical
Published in Atherosclerosis (01-10-2018)“…Familial hypercholesterolaemia (FH) is a genetic disorder affecting the metabolism of low-density lipoprotein (LDL) particles, leading to high LDL-cholesterol…”
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Overview of a collaborative global effort to address the burden of familial hypercholesterolaemia
Published in Indian heart journal (01-03-2024)“…This is an overview of the EAS Familial Hypercholesterolaemia (FH) Studies Collaboration (FHSC) global consortium and registry (established 2015), which…”
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Obstructive sleep apnoea syndrome, endothelial function and markers of endothelialization. Changes after CPAP
Published in PloS one (27-03-2015)“…This study tries to assess the endothelial function in vivo using flow-mediated dilatation (FMD) and several biomarkers of endothelium formation/restoration…”
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Lower On-Treatment Low-Density Lipoprotein Cholesterol and Major Adverse Cardiovascular Events in Women and Men: Pooled Analysis of 10 ODYSSEY Phase 3 Alirocumab Trials
Published in Journal of the American Heart Association (18-09-2018)“…Background In statin trials, men and women derived similar relative risk reductions in cardiovascular events per 39 mg/ dL low-density lipoprotein cholesterol…”
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Lipoprotein(a) reductions from PCSK9 inhibition and major adverse cardiovascular events: Pooled analysis of alirocumab phase 3 trials
Published in Atherosclerosis (01-09-2019)“…Elevated lipoprotein(a) [Lp(a)] levels are considered a causal factor for cardiovascular disease. In phase 3 ODYSSEY trials, alirocumab reduced levels of…”
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Effect of pitavastatin on glucose, HbA1c and incident diabetes: A meta-analysis of randomized controlled clinical trials in individuals without diabetes
Published in Atherosclerosis (01-08-2015)“…Abstract Aims Whether adverse effect of statins on glycaemic indices is common to all statins remains controversial and as yet data for pitavastatin are…”
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Triglycerides and residual risk
Published in Current opinion in endocrinology, diabetes, and obesity (01-04-2020)“…To review the recent evidence from observational/genetic/interventional studies addressing triglycerides and residual cardiovascular risk (CVRisk). Large…”
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Impact of the first wave of the COVID-19 pandemic on non-COVID inpatient care in southern Spain
Published in Scientific reports (30-01-2023)“…We assessed the impact of the first wave of COVID-19 pandemic on non-COVID hospital admissions, non-COVID mortality, factors associated with non-COVID…”
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Fungal microbiota in newborn infants with and without respiratory distress syndrome
Published in PloS one (10-04-2024)“…Pneumocytis jirovecii infection in preterm newborns has recently been associated with neonatal respiratory distress syndrome and bronchopulmonary dysplasia…”
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Impact of the COVID-19 pandemic on psychotropic prescribing: a systematic review
Published in BMJ open (25-09-2024)“…ObjectivesThe global prevalence of mental health disorders has risen significantly since the beginning of the COVID-19 pandemic. The pandemic has additionally…”
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Total and Fetal Circulating Cell-Free DNA, Angiogenic, and Antiangiogenic Factors in Preeclampsia and HELLP Syndrome
Published in American journal of hypertension (01-07-2017)“…Preeclampsia (PE) is a hypertensive disorder of pregnancy characterized by hypertension and proteinuria. The HELLP syndrome is the most severe form of PE. The…”
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Cerebrovascular Disease and Statins
Published in Frontiers in cardiovascular medicine (02-12-2021)“…Elevated low-density lipoprotein-cholesterol (LDL-C) is a causal factor for the development of atherosclerotic cardiovascular disease (ASCVD); accordingly,…”
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Fibrate therapy and flow-mediated dilation: A systematic review and meta-analysis of randomized placebo-controlled trials
Published in Pharmacological research (01-09-2016)“…[Display omitted] Flow-mediated dilation (FMD) of the brachial artery reflects endothelium-dependent vasodilator function; since it correlates with coronary…”
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Premature morbidity and mortality associated with potentially undiagnosed familial hypercholesterolemia in the general population
Published in American journal of preventive cardiology (01-09-2023)“…Familial hypercholesterolemia (FH) is common, but underdiagnosed, and few systematic early screening programs exist. To assess health outcomes among those with…”
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Relation of Fasting Triglyceride-Rich Lipoprotein Cholesterol to Coronary Artery Calcium Score (from the ELSA-Brasil Study)
Published in The American journal of cardiology (01-05-2017)“…Although low-density lipoprotein cholesterol (LDL-C) is widely accepted as the principal lipid fraction associated with atherosclerosis, emerging evidence…”
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Ensemble machine learning methods in screening electronic health records: A scoping review
Published in DIGITAL HEALTH (01-01-2023)“…Background Electronic health records provide the opportunity to identify undiagnosed individuals likely to have a given disease using machine learning…”
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Abnormal levels of antioxidant defenses in a large sample of patients with hypertensive disorders of pregnancy
Published in Hypertension research (01-03-2012)“…Increased levels of oxidative stress have been demonstrated in Preeclampsia in previous studies, but this finding has not been established in other…”
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Differences in the prevalence of metabolic syndrome and levels of C-reactive protein after puerperium in women with hypertensive disorders during pregnancy
Published in Hypertension research (01-10-2010)“…To measure high-sensitivity C-reactive protein (hsCRP) levels and to assess the presence of metabolic syndrome (MS) after puerperium in women diagnosed with…”
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