Search Results - "Valladeau, J."

ANTIGEN PRESENTATION AND T CELL STIMULATION BY DENDRITIC CELLS by Guermonprez, Pierre, Valladeau, Jenny, Zitvogel, Laurence, Théry, Clotilde, Amigorena, Sebastian

“…Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides, and load these peptides onto major histocompatibility complex…”
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Accumulation of immature Langerhans cells in human lymph nodes draining chronically inflamed skin by Geissmann, F, Dieu-Nosjean, M C, Dezutter, C, Valladeau, J, Kayal, S, Leborgne, M, Brousse, N, Saeland, S, Davoust, J

“…The coordinated migration and maturation of dendritic cells (DCs) such as intraepithelial Langerhans cells (LCs) is considered critical for T cell priming in…”
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Identification of Mouse Langerin/CD207 in Langerhans Cells and Some Dendritic Cells of Lymphoid Tissues by Valladeau, Jenny, Clair-Moninot, Valerie, Dezutter-Dambuyant, Colette, Pin, Jean-Jacques, Kissenpfennig, Adrien, Mattei, Marie-Genevieve, Ait-Yahia, Smina, Bates, Elizabeth E. M, Malissen, Bernard, Koch, Franz, Fossiez, Francois, Romani, Nikolaus, Lebecque, Serge, Saeland, Sem

“…Human (h)Langerin/CD207 is a C-type lectin of Langerhans cells (LC) that induces the formation of Birbeck granules (BG). In this study, we have cloned a…”
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Respective involvement of TGF-beta and IL-4 in the development of Langerhans cells and non-Langerhans dendritic cells from CD34+ progenitors by Caux, C, Massacrier, C, Dubois, B, Valladeau, J, Dezutter-Dambuyant, C, Durand, I, Schmitt, D, Saeland, S

“…In vivo, dendritic cells (DC) form a network comprising different populations. In particular, Langerhans cells (LC) appear as a unique population of cells…”
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Immature Human Dendritic Cells Express Asialoglycoprotein Receptor Isoforms for Efficient Receptor-Mediated Endocytosis by Valladeau, Jenny, Duvert-Frances, Valerie, Pin, Jean-Jacques, Kleijmeer, Monique J, Ait-Yahia, Smina, Ravel, Odile, Vincent, Claude, Vega, Felix, Jr, Helms, Alison, Gorman, Dan, Zurawski, Sandra M, Zurawski, Gerard, Ford, John, Saeland, Sem

“…In a search for genes expressed by dendritic cells (DC), we have cloned cDNAs encoding different forms of an asialoglycoprotein receptor (ASGPR). The DC-ASGPR…”
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TGFβ Inhibits CD1d Expression on Dendritic Cells by Ronger-Savle, S., Valladeau, J., Claudy, A., Schmitt, D., Peguet-Navarro, J., Dezutter-Dambuyant, C., Thomas, L., Jullien, D.

“…The CD1 family of cell surface glycoprotein has been demonstrated to be a third lineage of antigen-presenting molecules for specific T cell responses. They…”
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Immune cell dysfunctions in breast cancer patients detected through whole blood multi-parametric flow cytometry assay by Verronèse, E., Delgado, A., Valladeau-Guilemond, J., Garin, G., Guillemaut, S., Tredan, O., Ray-Coquard, I., Bachelot, T., N'Kodia, A., Bardin-Dit-Courageot, C., Rigal, C., Pérol, D., Caux, C., Ménétrier-Caux, C.

“…Monitoring functional competence of immune cell populations in clinical routine represents a major challenge. We developed a whole-blood assay to monitor…”
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Cutaneous dendritic cells by Valladeau, Jenny, Saeland, Sem

“…Cutaneous dendritic cells (DC) include epidermal Langerhans cells (LC), interstitial/dermal dendritic cells (DDC), as well as plasmacytoid DC (pDC) that occur…”
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Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules by Valladeau, J, Ravel, O, Dezutter-Dambuyant, C, Moore, K, Kleijmeer, M, Liu, Y, Duvert-Frances, V, Vincent, C, Schmitt, D, Davoust, J, Caux, C, Lebecque, S, Saeland, S

“…We have identified a type II Ca2+-dependent lectin displaying mannose-binding specificity, exclusively expressed by Langerhans cells (LC), and named Langerin…”
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Early events in HIV transmission through a human reconstructed vaginal mucosa by BOUSCHBACHER, Marielle, BOMSEL, Morgane, VERRONESE, Estelle, GOFFLO, Sandrine, GANOR, Yonatan, DEZUTTER-DAMBUYANT, Colette, VALLADEAU, Jenny

“…The early steps of HIV entry into intact vaginal mucosa still need to be clarified. Here we investigated how HIV translocated across the vaginal…”
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In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas by Bell, D, Chomarat, P, Broyles, D, Netto, G, Harb, G M, Lebecque, S, Valladeau, J, Davoust, J, Palucka, K A, Banchereau, J

“…We have analyzed the presence of immature and mature dendritic cells (DCs) within adenocarcinoma of the breast using immunohistochemistry. Immature DCs were…”
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Structural Studies of Langerin and Birbeck Granule: A Macromolecular Organization Model by Thépaut, Michel, Valladeau, Jenny, Nurisso, Alessandra, Kahn, Richard, Arnou, Bertrand, Vivès, Corinne, Saeland, Sem, Ebel, Christine, Monnier, Carine, Dezutter-Dambuyant, Colette, Imberty, Anne, Fieschi, Franck

“…Dendritic cells, a sentinel immunity cell lineage, include different cell subsets that express various C-type lectins. For example, epidermal Langerhans cells…”
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Differentiation of Langerhans cells in Langerhans cell histiocytosis by Geissmann, Frederic, Lepelletier, Yves, Fraitag, Sylvie, Valladeau, Jenny, Bodemer, Christine, Debré, Marianne, Leborgne, Michelle, Saeland, Sem, Brousse, Nicole

“…Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges…”
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Langerin/CD207 sheds light on formation of birbeck granules and their possible function in Langerhans cells by Valladeau, Jenny, Dezutter-Dambuyant, Colette, Saeland, Sem

“…Langerhans cells (LCs) are immature dendritic cells of epidermis and epithelia, playing a sentinel role through their specialized function in antigen capture,…”
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A CD1a+/CD11c+ Subset of Human Blood Dendritic Cells Is a Direct Precursor of Langerhans Cells by Ito, Tomoki, Inaba, Muneo, Inaba, Kayo, Toki, Junko, Sogo, Shinji, Iguchi, Tomoko, Adachi, Yasushi, Yamaguchi, Kazuyuki, Amakawa, Ryuichi, Valladeau, Jenny, Saeland, Sem, Fukuhara, Shirou, Ikehara, Susumu

“…Based on the relative expression of CD11c and CD1a, we have identified three fractions of dendritic cells (DCs) in human peripheral blood, including a direct…”
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1815P Prognostic value of conventional type 1 dendritic cells in breast cancer patients by Gobbini, E., Doffin, A.C., Hubert, M., Sakref, C., Rocca, Y., Caux, C., Valladeau-Guilemond, J.

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The monoclonal antibody DCGM4 recognizes Langerin, a protein specific of Langerhans cells, and is rapidly internalized from the cell surface by Valladeau, Jenny, Duvert‐Frances, Valérie, Pin, Jean‐Jacques, Dezutter‐Dambuyant, Colette, Vincent, Claude, Massacrier, Catherine, Vincent, Jérôme, Yoneda, Kozo, Banchereau, Jacques, Caux, Christophe, Davoust, Jean, Saeland, Sem

“…We generated monoclonal antibody (mAb) DCGM4 by immunization with human dendritic cells (DC) from CD34+ progenitors cultured with granulocyte‐macrophage…”
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APCs Express DCIR, a Novel C-Type Lectin Surface Receptor Containing an Immunoreceptor Tyrosine-Based Inhibitory Motif by Bates, Elizabeth E. M, Fournier, Nathalie, Garcia, Eric, Valladeau, Jenny, Durand, Isabelle, Pin, Jean-Jacques, Zurawski, Sandra M, Patel, Sejal, Abrams, John S, Lebecque, Serge, Garrone, Pierre, Saeland, Sem

“…We have identified a novel member of the calcium-dependent (C-type) lectin family. This molecule, designated DCIR (for dendritic cell (DC) immunoreceptor), is…”
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Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin by de Saint-Vis, Blandine, Bouchet, Caroline, Gautier, Grégory, Valladeau, Jenny, Caux, Christophe, Garrone, Pierre

“…Eph receptor tyrosine kinases and their ligands, the ephrins, have been primarily described in the nervous system for their roles in axon guidance,…”
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Mixed Langerhans cell and interstitial/dermal dendritic cell subsets emanating from monocytes in Th2-mediated inflammatory conditions respond differently to proinflammatory stimuli by Bechetoille, Nicolas, André, Valérie, Valladeau, Jenny, Perrier, Eric, Dezutter‐Dambuyant, Colette

“…The skin harbors two dendritic cell (DC) subsets, Langerhans cells (LC) and interstitial/dermal DC (IDDC), which traffic to lymph nodes after inflammation and…”
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