Search Results - "Valladares, Denisse"

Changes in oxidative stress, inflammation and muscle damage markers following eccentric versus concentric cycling in older adults by González-Bartholin, Roberto, Mackay, Karen, Valladares, Denisse, Zbinden-Foncea, Hermann, Nosaka, Kazunori, Peñailillo, Luis

“…Purpose To compare concentric and eccentric cycling performed by older adults for metabolic demand and post-exercise oxidative stress, inflammation and muscle…”
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NOX2 Inhibition Impairs Early Muscle Gene Expression Induced by a Single Exercise Bout by Henríquez-Olguín, Carlos, Díaz-Vegas, Alexis, Utreras-Mendoza, Yildy, Campos, Cristian, Arias-Calderón, Manuel, Llanos, Paola, Contreras-Ferrat, Ariel, Espinosa, Alejandra, Altamirano, Francisco, Jaimovich, Enrique, Valladares, Denisse M

“…Reactive oxygen species (ROS) participate as signaling molecules in response to exercise in skeletal muscle. However, the source of ROS and the molecular…”
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Mitochondrial Calcium Increase Induced by RyR1 and IP3R Channel Activation After Membrane Depolarization Regulates Skeletal Muscle Metabolism by Díaz-Vegas, Alexis R, Cordova, Alex, Valladares, Denisse, Llanos, Paola, Hidalgo, Cecilia, Gherardi, Gaia, De Stefani, Diego, Mammucari, Cristina, Rizzuto, Rosario, Contreras-Ferrat, Ariel, Jaimovich, Enrique

“…We hypothesize that both type-1 ryanodine receptor (RyR1) and IP -receptor (IP R) calcium channels are necessary for the mitochondrial Ca increase caused by…”
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GSK-3β/NFAT Signaling Is Involved in Testosterone-Induced Cardiac Myocyte Hypertrophy by Duran, Javier, Oyarce, Cesar, Pavez, Mario, Valladares, Denisse, Basualto-Alarcon, Carla, Lagos, Daniel, Barrientos, Genaro, Troncoso, Mayarling Francisca, Ibarra, Cristian, Estrada, Manuel

“…Testosterone induces cardiac hypertrophy through a mechanism that involves a concerted crosstalk between cytosolic and nuclear signaling pathways. Nuclear…”
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Electrical stimuli are anti-apoptotic in skeletal muscle via extracellular ATP. Alteration of this signal in Mdx mice is a likely cause of dystrophy by Valladares, Denisse, Almarza, Gonzalo, Contreras, Ariel, Pavez, Mario, Buvinic, Sonja, Jaimovich, Enrique, Casas, Mariana

“…ATP signaling has been shown to regulate gene expression in skeletal muscle and to be altered in models of muscular dystrophy. We have previously shown that in…”
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Nifedipine treatment reduces resting calcium concentration, oxidative and apoptotic gene expression, and improves muscle function in dystrophic mdx mice by Altamirano, Francisco, Valladares, Denisse, Henríquez-Olguín, Carlos, Casas, Mariana, López, Jose R, Allen, Paul D, Jaimovich, Enrique

“…Duchenne Muscular Dystrophy (DMD) is a recessive X-linked genetic disease, caused by mutations in the gene encoding dystrophin. DMD is characterized in humans…”
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Role of specialized pro-resolving mediators on inflammation, cardiometabolic health, disease progression, and quality of life after omega-3 PUFA supplementation and aerobic exercise training in individuals with rheumatoid arthritis: a randomized 16-week, placebo-controlled interventional trial [version 1; peer review: 2 approved, 1 approved with reservations] by Jannas-Vela, Sebastián, Candia, Alejandro A, Peñailillo, Luis, Barrios-Troncoso, Paola, Zapata-Urzúa, Jeremy, Rey-Puente, Joanny, Aukema, Harold M, Mutch, David M, Valenzuela, Rodrigo, Valladares-Ide, Denisse

“…Background: Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by autoantibody production and synovial membrane damage. It significantly…”
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NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle by Jorquera, Gonzalo, Russell, Javier, Monsalves-Álvarez, Matías, Cruz, Gonzalo, Valladares-Ide, Denisse, Basualto-Alarcón, Carla, Barrientos, Genaro, Estrada, Manuel, Llanos, Paola

“…Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding…”
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Changes in Blood Markers of Oxidative Stress, Inflammation and Cardiometabolic Patients with COPD after Eccentric and Concentric Cycling Training by Valero-Breton, Mayalen, Valladares-Ide, Denisse, Álvarez, Cristian, Peñailillo, Reyna S, Peñailillo, Luis

“…Chronic obstructive pulmonary disease (COPD) patients manifest muscle dysfunction and impaired muscle oxidative capacity, which result in reduced exercise…”
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Editorial: Spotlight on aging: physiology, prevention, and management of skeletal muscle atrophy by Marzuca-Nassr, Gabriel Nasri, Peñailillo, Luis, Valladares-Ide, Denisse, Martinez-Huenchullan, Sergio, Curi, Rui, Hirabara, Sandro Massao, Vitzel, Kaio Fernando

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Effects of eccentric, concentric and eccentric/concentric training on muscle function and mass, functional performance, cardiometabolic health, quality of life and molecular adaptations of skeletal muscle in COPD patients: a multicentre randomised trial by Peéailillo, Luis, Valladares-Ide, Denisse, Jannas-Velas, Sebastián, Flores-Opazo, Marcelo, Jalón, Mauricio, Mendoza, Laura, Nuéez, Ingrid, Diaz-Patiéo, Orlando

“…Abstract Background Chronic obstructive pulmonary disease (COPD) is the third cause of death worldwide. COPD is characterised by dyspnoea, limited exercise…”
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High extracellular ATP levels released through pannexin-1 channels mediate inflammation and insulin resistance in skeletal muscle fibres of diet-induced obese mice by Jorquera, Gonzalo, Meneses-Valdés, Roberto, Rosales-Soto, Giovanni, Valladares-Ide, Denisse, Campos, Cristian, Silva-Monasterio, Mónica, Llanos, Paola, Cruz, Gonzalo, Jaimovich, Enrique, Casas, Mariana

“…Aims/hypothesis Skeletal muscle is a key target organ for insulin’s actions and is the main regulator of blood glucose. In obese individuals and animal models,…”
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Moderate Exercise in Spontaneously Hypertensive Rats Is Unable to Activate the Expression of Genes Linked to Mitochondrial Dynamics and Biogenesis in Cardiomyocytes by Quiroga, Clara, Mancilla, Georthan, Oyarzun, Ingrid, Tapia, Anita, Caballero, Mia, Gabrielli, Luigi A, Valladares-Ide, Denisse, Del Campo, Andrea, Castro, Pablo F, Verdejo, Hugo E

“…Hypertension (HTN) is a public health concern and a major preventable cause of cardiovascular disease (CVD). When uncontrolled, HTN may lead to adverse cardiac…”
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Next steps to advance general physical activity recommendations towards physical exercise prescription: a narrative review by Festa, Raúl Ricardo, Jofré-Saldía, Emilio, Candia, Alejandro A, Monsalves-Álvarez, Matías, Flores-Opazo, Marcelo, Peñailillo, Luis, Marzuca-Nassr, Gabriel Nasri, Aguilar-Farias, Nicolas, Fritz-Silva, Nicole, Cancino-Lopez, Jorge, Soto-Sánchez, Johana, Sepulveda, Carlos, Huerta Ojeda, Álvaro, Núñez-Espinosa, Cristian, Valladares-Ide, Denisse, Jannas-Vela, Sebastian

“…Physical inactivity is a major health concern, associated with the development of several non-communicable diseases and with an increased mortality rate…”
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Community strategies for health promotion and prevention of chronic non-communicable diseases with a focus on physical activity and nutrition: the URO/FOCOS study protocol by Monsalves-Álvarez, Matías, Solis-Soto, María Teresa, Burrone, María Soledad, Candia, Alejandro A, Jofré-Saldía, Emilio, Espinoza, Gabriela, Flores-Opazo, Marcelo, Puebla, Carlos, Valladares-Ide, Denisse, Jannas-Vela, Sebastián

“…Non-communicable diseases (NCDs) account for 71% of all annual deaths, totaling 41 million people worldwide. The development and progression of these diseases…”
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Defective fasting-induced PKA activation impairs adipose tissue glycogen degradation in obese Zucker rats by Flores-Opazo, Marcelo, Trieu, Jennifer, Naim, Timur, Valladares-Ide, Denisse, Zbinden-Foncea, Hermann, Stapleton, David

“…Background Obesity is associated with development of insulin resistance in adipose tissue (AT). Human obesity has been associated with increased glycogen…”
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Changes in pulmonary and plasma oxidative stress and inflammation following eccentric and concentric cycling in stable COPD patients by Valladares-Ide, Denisse, Bravo, Maria José, Carvajal, Ana, Araneda, Oscar F., Tuesta, Marcelo, Reyes, Alvaro, Peñailillo, Reyna, Peñailillo, Luis

“…Purpose The purpose of this study was to compare pulmonary and plasma markers of oxidative stress and inflammation after concentric and eccentric cycling bouts…”
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Do adenosine receptors offer new therapeutic options for diabetic nephropathy? by San Martín, Rody, Valladares, Denisse, Roa, Horacio, Troncoso, Evelin, Sobrevia, Luis

“…Diabetes mellitus is currently considered to be an epidemic disease. Approximately a third of individuals with type 1 and type 2 diabetes develop persistent…”
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Correction to: High extracellular ATP levels released through pannexin-1 channels mediate inflammation and insulin resistance in skeletal muscle fibres of diet-induced obese mice by Jorquera, Gonzalo, Meneses-Valdés, Roberto, Rosales-Soto, Giovanni, Valladares-Ide, Denisse, Campos, Cristian, Silva-Monasterio, Mónica, Llanos, Paola, Cruz, Gonzalo, Jaimovich, Enrique, Casas, Mariana

“…A Correction to this paper has been published: https://doi.org/10.1007/s00125-021-05451-1…”
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IP3 receptor blockade restores autophagy and mitochondrial function in skeletal muscle fibers of dystrophic mice by Valladares, Denisse, Utreras-Mendoza, Yildy, Campos, Cristian, Morales, Camilo, Diaz-Vegas, Alexis, Contreras-Ferrat, Ariel, Westermeier, Francisco, Jaimovich, Enrique, Marchi, Saverio, Pinton, Paolo, Lavandero, Sergio

“…Duchenne muscular dystrophy (DMD) is characterized by a severe and progressive destruction of muscle fibers associated with altered Ca2+ homeostasis. We have…”
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