Search Results - "Valkov, Nikola I."

Tumor p53 status and response to topoisomerase II inhibitors by Valkov, Nikola I., Sullivan, Daniel M.

“…It is thought that when tumor cells are treated with anticancer drugs, they die through the apoptotic pathway and that cell resistance to cancer chemotherapy…”
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The cytoplasmic trafficking of DNA topoisomerase IIα correlates with etoposide resistance in human myeloma cells by Engel, Roxane, Valkov, Nikola I, Gump, Jana L, Hazlehurst, Lori, Dalton, William S, Sullivan, Daniel M

“…In this study we have investigated the role of topoisomerase (topo) IIα trafficking in cellular drug resistance. To accomplish this, it was necessary to…”
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The cytoplasmic trafficking of DNA topoisomerase IIalpha correlates with etoposide resistance in human myeloma cells by Engel, Roxane, Valkov, Nikola I, Gump, Jana L, Hazlehurst, Lori, Dalton, William S, Sullivan, Daniel M

“…In this study we have investigated the role of topoisomerase (topo) IIalpha trafficking in cellular drug resistance. To accomplish this, it was necessary to…”
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Effects of wild-type p53 expression on the quantity and activity of topoisomerase IIα and β in various human cancer cell lines by Hochhauser, Daniel, Valkov, Nikola I., Gump, Jana L., Wei, Irene, O'Hare, Carolyn, Hartley, John, Fan, Jianguo, Bertino, Joseph R., Banerjee, Debabrata, Sullivan, Daniel M.

“…The p53 null HL‐60 cell line was transfected with plasmids coding for either the wild‐type p53 or mutant p53 gene. The stable expression of wild‐type p53…”
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Effects of wild-type p53 expression on the quantity and activity of topoisomerase II? and ? in various human cancer cell lines by Hochhauser, Daniel, Valkov, Nikola I., Gump, Jana L., Wei, Irene, O'Hare, Carolyn, Hartley, John, Fan, Jianguo, Bertino, Joseph R., Banerjee, Debabrata, Sullivan, Daniel M.

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Quantitative immunofluorescence and immunoelectron microscopy of the topoisomerase IIα associated with nuclear matrices from wild-type and drug-resistant Chinese hamster ovary cell lines by Valkov, Nikola I., Gump, Jana L., Sullivan, Daniel M.

“…Topo IIα is considered an important constituent of the nuclear matrix, serving as a fastener of DNA loops to the underlying filamentous scaffolding network. To…”
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Prolonged activation of the mitogen-activated protein kinase pathway is required for macrophage-like differentiation of a human myeloid leukemic cell line by XIAOTANG HU, MOSCINSKI, L. C, VALKOV, N. I, FISHER, A. B, HILL, B. J, ZUCKERMAN, K. S

“…The role of the mitogen-activated protein kinase (MAPK) signal transduction pathway in the proliferation of mammalian cells has been well established. However,…”
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