Search Results - "Valk, Gerlof"

Multiple Endocrine Neoplasia Type 1: Latest Insights by Brandi, Maria Luisa, Agarwal, Sunita K, Perrier, Nancy D, Lines, Kate E, Valk, Gerlof D, Thakker, Rajesh V

“…Abstract Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an autosomal dominant pattern, is continuing to raise great…”
Get full text

Update on the clinical management of multiple endocrine neoplasia type 1 by Pieterman, Carolina R. C., Valk, Gerlof D.

“…This review provides an overview of novel insights in the clinical management of patients with Multiple Endocrine Neoplasia Type 1, focusing on the last decade…”
Get full text

The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets by van Riet, Job, van de Werken, Harmen J. G., Cuppen, Edwin, Eskens, Ferry A. L. M., Tesselaar, Margot, van Veenendaal, Linde M., Klümpen, Heinz-Josef, Dercksen, Marcus W., Valk, Gerlof D., Lolkema, Martijn P., Sleijfer, Stefan, Mostert, Bianca

“…Metastatic and locally-advanced neuroendocrine neoplasms (aNEN) form clinically and genetically heterogeneous malignancies, characterized by distinct prognoses…”
Get full text

Breast-Cancer Predisposition in Multiple Endocrine Neoplasia Type 1 by Dreijerink, Koen M.A, Goudet, Pierre, Burgess, John R, Valk, Gerlof D

“…Women with multiple endocrine neoplasia type 1 related to mutations in the gene encoding menin ( MEN1 ) have approximately twice the risk of breast cancer as…”
Get full text

Efficacy of α-Blockers on Hemodynamic Control during Pheochromocytoma Resection: A Randomized Controlled Trial by Buitenwerf, Edward, Osinga, Thamara E, Timmers, Henri J L M, Lenders, Jacques W M, Feelders, Richard A, Eekhoff, Elisabeth M W, Haak, Harm R, Corssmit, Eleonora P M, Bisschop, Peter H L T, Valk, Gerlof D, Veldman, Ronald Groote, Dullaart, Robin P F, Links, Thera P, Voogd, Magiel F, Wietasch, Götz J K G, Kerstens, Michiel N

“…Abstract Context Pretreatment with α-adrenergic receptor blockers is recommended to prevent hemodynamic instability during resection of a pheochromocytoma or…”
Get full text

Multiple Endocrine Neoplasia Type 1 and the Pancreas: Diagnosis and Treatment of Functioning and Non-Functioning Pancreatic and Duodenal Neuroendocrine Neoplasia within the MEN1 Syndrome - An International Consensus Statement by Niederle, Bruno, Selberherr, Andreas, Bartsch, Detlef K, Brandi, Maria L, Doherty, Gerard M, Falconi, Massimo, Goudet, Pierre, Halfdanarson, Thorvardur R, Ito, Tetsuhide, Jensen, Robert T, Larghi, Alberto, Lee, Lingaku, Öberg, Kjell, Pavel, Marianne, Perren, Aurel, Sadowski, Samira M, Tonelli, Francesco, Triponez, Frédéric, Valk, Gerlof D, O'Toole, Dermot, Scott-Coombes, David, Thakker, Rajesh V, Thompson, Geoffrey B, Treglia, Giorgio, Wiedenmann, Bertram

“…The better understanding of the biological behavior of multiple endocrine neoplasia type 1 (MEN1) organ manifestations and the increase in clinical experience…”
Get more information

Endoscopic full-thickness resection of gastric and duodenal subepithelial lesions using a new, flat-based over-the-scope clip by Kappelle, Wouter F. W., Backes, Yara, Valk, Gerlof D., Moons, Leon M. G., Vleggaar, Frank P.

“…Background Surgical resection of upper gastrointestinal (GI) subepithelial tumors (SETs) is associated with significant morbidity and mortality. A new…”
Get full text

Lifestyle Factors and Development and Natural Course of Gastroenteropancreatic Neuroendocrine Tumors: A Review of the Literature by Bogaards, Marit, May, Anne M, Hassan, Faduma A, Valk, Gerlof D, van Leeuwaarde, Rachel S

“…The rarity of neuroendocrine tumors (NETs) and their heterogeneous presentation complicate the identification of risk factors for their development and natural…”
Get more information

CDC73-Related Disorders: Clinical Manifestations and Case Detection in Primary Hyperparathyroidism by van der Tuin, Karin, Tops, Carli M J, Adank, Muriel A, Cobben, Jan-Maarten, Hamdy, Neveen A T, Jongmans, Marjolijn C, Menko, Fred H, van Nesselrooij, Bernadette P M, Netea-Maier, Romana T, Oosterwijk, Jan C, Valk, Gerlof D, Wolffenbuttel, Bruce H R, Hes, Frederik J, Morreau, Hans

“…Abstract Context Heterozygous pathogenic germline variants in CDC73 predispose to the development of primary hyperparathyroidism (pHPT) and, less frequently,…”
Get full text

Blood Molecular Genomic Analysis Predicts the Disease Course of Gastroenteropancreatic Neuroendocrine Tumor Patients: A Validation Study of the Predictive Value of the NETest by van Treijen, Mark J C, van der Zee, Dennis, Heeres, Birthe C, Staal, Femke C R, Vriens, Menno R, Saveur, Lisette J, Verbeek, Wieke H M, Korse, Catharina M, Maas, Monique, Valk, Gerlof D, Tesselaar, Margot E T

“…Reliable prediction of disease status is a major challenge in managing gastroenteropancreatic neuroendocrine tumors (GEP-NETs). The aim of the study was to…”
Get more information

Diagnostic and management strategies for pNETs in Von Hippel–Lindau: a systematic review by Ahmad, Saya, Naber, Myrthe R, Giles, Rachel H, Valk, Gerlof D, van Leeuwaarde, Rachel S

“…Pancreatic neuroendocrine tumors (pNETs) in Von Hippel–Lindau (VHL) disease have a relatively good prognosis. However, a subset of pNETs metastasize and…”
Get full text

Patient education for preventing diabetic foot ulceration by Dorresteijn, Johannes A N, Kriegsman, Didi M W, Assendelft, Willem J J, Valk, Gerlof D

“…Ulceration of the feet, which can result in loss of limbs and even death, is one of the major health problems for people with diabetes mellitus. To assess the…”
Get more information

Long-Term Natural Course of Small Nonfunctional Pancreatic Neuroendocrine Tumors in MEN1—Results From the Dutch MEN1 Study Group by Pieterman, Carolina R C, de Laat, Joanne M, Twisk, Jos W R, van Leeuwaarde, Rachel S, de Herder, Wouter W, Dreijerink, Koen M A, Hermus, Ad R M M, Dekkers, Olaf M, van der Horst-Schrivers, Anouk N A, Drent, Madeleine L, Bisschop, Peter H, Havekes, Bastiaan, Borel Rinkes, Inne H M, Vriens, Menno R, Valk, Gerlof D

“…Abstract Background Pancreatic neuroendocrine tumors (pNETs) are highly prevalent in patients with multiple endocrine neoplasia type 1 (MEN1), and metastatic…”
Get full text

MEN1-Dependent Breast Cancer: Indication for Early Screening? Results From the Dutch MEN1 Study Group by van Leeuwaarde, Rachel S., Dreijerink, Koen M., Ausems, Margreet G., Beijers, Hanneke J., Dekkers, Olaf M., de Herder, Wouter W., van der Horst-Schrivers, Anouk N., Drent, Madeleine L., Bisschop, Peter H., Havekes, Bas, Peeters, Petra H. M., Pijnappel, Ruud M., Vriens, Menno R., Valk, Gerlof D.

“…Abstract Objective: Multiple endocrine neoplasia type 1 (MEN1) is associated with an early-onset elevated breast cancer risk. This finding potentially has…”
Get full text

Long-Term Natural Course of Pituitary Tumors in Patients With MEN1: Results From the DutchMEN1 Study Group (DMSG) by de Laat, Joanne M, Dekkers, Olaf M, Pieterman, Carolina R. C, Kluijfhout, Wouter P, Hermus, Ad R, Pereira, Alberto M, van der Horst-Schrivers, Anouk N, Drent, Madeleine L, Bisschop, Peter H, Havekes, Bas, de Herder, Wouter W, Valk, Gerlof D

“…Context: Guidelines advise lifelong radiological followup for asymptomatic pituitary adenomas (PITs) because of the risk for growth and subsequent visual field…”
Get full text

Early and Late Complications After Surgery for MEN1-related Nonfunctioning Pancreatic Neuroendocrine Tumors by Nell, Sjoerd, Borel Rinkes, Inne H M, Verkooijen, Helena M, Bonsing, Bert A, van Eijck, Casper H, van Goor, Harry, de Kleine, Ruben H J, Kazemier, Geert, Nieveen van Dijkum, Elisabeth J, Dejong, Cornelis H C, Valk, Gerlof D, Vriens, Menno R

“…OBJECTIVE:To estimate short and long-term morbidity after pancreatic surgery for multiple endocrine neoplasia type 1 (MEN1)-related nonfunctioning pancreatic…”
Get full text

Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors by de Wilde, Roeland F, Heaphy, Christopher M, Maitra, Anirban, Meeker, Alan K, Edil, Barish H, Wolfgang, Christopher L, Ellison, Trevor A, Schulick, Richard D, Molenaar, I Quintus, Valk, Gerlof D, Vriens, Menno R, Borel Rinkes, Inne H M, Offerhaus, G Johan A, Hruban, Ralph H, Matsukuma, Karen E

“…Approximately 45% of sporadic well-differentiated pancreatic neuroendocrine tumors harbor mutations in either ATRX (alpha thalassemia/mental retardation…”
Get full text

Precision radiotherapy using MR-linac for pancreatic neuroendocrine tumors in MEN1 patients (PRIME): a protocol for a phase I-II trial, and systematic review on available evidence for radiotherapy of pNETs by van Vliembergen, Eline N M, Eijkelenkamp, Hidde, Valk, Gerlof D, Vriens, Menno R, Meijer, Gert J, Intven, Martijn P W, de Laat, Joanne M

“…Surgical resection is the standard of care for the treatment of pancreatic neuro-endocrine tumors (pNETs) in patients with Multiple Endocrine Neoplasia Type 1…”
Get full text

Assessing Outcomes After Adrenalectomy for Primary Aldosteronism – Early is Accurate: Retrospective Cohort Study by Suurd, Diederik P.D., Vorselaars, Wessel M.C.M., Van Beek, Dirk-Jan, Borel Rinkes, Inne H.M., Spiering, Wilko, Valk, Gerlof D., Vriens, Menno R.

“…We aimed to investigate the postoperative trend in blood pressure (BP)-related outcomes [BP and antihypertensive (AHT) drug use] during the year following…”
Get full text

Management of MEN1 Related Nonfunctioning Pancreatic NETs: A Shifting Paradigm: Results From the DutchMEN1 Study Group by Nell, Sjoerd, Verkooijen, Helena M, Pieterman, Carolina R C, de Herder, Wouter W, Hermus, Ad R, Dekkers, Olaf M, van der Horst-Schrivers, Anouk N, Drent, Madeleine L, Bisschop, Peter H, Havekes, Bas, Borel Rinkes, Inne H M, Vriens, Menno R, Valk, Gerlof D

“…OBJECTIVE:To assess if surgery for Multiple Endocrine Neoplasia type 1 (MEN1) related nonfunctioning pancreatic neuroendocrine tumors (NF-pNETs) is effective…”
Get full text