Search Results - "Valero, Ruth A"
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1
RhoA-ROCK and p38MAPK-MSK1 mediate vitamin D effects on gene expression, phenotype, and Wnt pathway in colon cancer cells
Published in The Journal of cell biology (17-11-2008)“…The active vitamin D metabolite 1,25-dihydroxyvitamin D₃ (1,25(OH)₂D₃) inhibits proliferation and promotes differentiation of colon cancer cells through the…”
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2
Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate
Published in The Journal of physiology (15-02-2006)“…Store-operated Ca 2+ entry (SOCE) is a ubiquitous Ca 2+ influx pathway involved in control of multiple cellular and physiological processes including cell…”
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Journal Article -
3
Mitochondrial Ca2+ Overload Underlies Aβ Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs
Published in PloS one (23-07-2008)“…Dysregulation of intracellular Ca2+ homeostasis may underlie amyloid β peptide (Aβ) toxicity in Alzheimer's Disease (AD) but the mechanism is unknown. In…”
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4
Nonsteroidal Anti-inflammatory Drugs Inhibit Vascular Smooth Muscle Cell Proliferation by Enabling the Ca2+-dependent Inactivation of Calcium Release-activated Calcium/Orai Channels Normally Prevented by Mitochondria
Published in The Journal of biological chemistry (06-05-2011)“…Abnormal vascular smooth muscle cell (VSMC) proliferation contributes to occlusive and proliferative disorders of the vessel wall. Salicylate and other…”
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5
Mitochondria sustain store-operated currents in colon cancer cells but not in normal colonic cells: reversal by non-steroidal anti-inflammatory drugs
Published in Oncotarget (15-08-2017)“…Tumor cells undergo a critical remodeling of intracellular Ca homeostasis that contribute to important cancer hallmarks. Store-operated Ca entry (SOCE), a Ca…”
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6
The role of mitochondrial potential in control of calcium signals involved in cell proliferation
Published in Cell calcium (Edinburgh) (01-09-2008)“…Summary Store-operated Ca2+ entry (SOCE), a Ca2+ influx pathway involved in cell proliferation, depends on mitochondrial Ca2+ uptake, a Ca2+ influx that is…”
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7
Structural Determinants Allowing Endolysosomal Sorting and Degradation of Endosomal GTPases
Published in Traffic (Copenhagen, Denmark) (01-09-2010)“…Rapid control of protein degradation is usually achieved through the ubiquitin-proteasome pathway. We recently found that the short-lived GTPase RhoB is…”
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8
Mitochondrial Ca2+ overload underlies Abeta oligomers neurotoxicity providing an unexpected mechanism of neuroprotection by NSAIDs
Published in PloS one (23-07-2008)“…Dysregulation of intracellular Ca(2+) homeostasis may underlie amyloid beta peptide (Abeta) toxicity in Alzheimer's Disease (AD) but the mechanism is unknown…”
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Journal Article -
9
Mitochondrial Ca.sup.2+ Overload Underlies A[beta] Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs
Published in PloS one (23-07-2008)“…Dysregulation of intracellular Ca.sup.2+ homeostasis may underlie amyloid [beta] peptide (A[beta]) toxicity in Alzheimer's Disease (AD) but the mechanism is…”
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Journal Article -
10
Mitochondrial Ca super(2+) Overload Underlies A beta Oligomers Neurotoxicity Providing an Unexpected Mechanism of Neuroprotection by NSAIDs
Published in PloS one (01-01-2008)“…Dysregulation of intracellular Ca super(2+) homeostasis may underlie amyloid beta peptide (A beta ) toxicity in Alzheimer's Disease (AD) but the mechanism is…”
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Journal Article -
11
Cell proliferation depends on mitochondrial Ca 2+ uptake: inhibition by salicylate
Published in The Journal of physiology (01-02-2006)“…Store‐operated Ca 2+ entry (SOCE) is a ubiquitous Ca 2+ influx pathway involved in control of multiple cellular and physiological processes including cell…”
Get full text
Journal Article -
12
Cell proliferation depends on mitochondrial Ca super(2+) uptake: inhibition by salicylate
Published in The Journal of physiology (01-02-2006)“…Store-operated Ca super(2+) entry (SOCE) is a ubiquitous Ca super(2+) influx pathway involved in control of multiple cellular and physiological processes…”
Get full text
Journal Article