Search Results - "Valenzuela, Michael J"

Brain reserve and cognitive decline: a non-parametric systematic review by Valenzuela, Michael J, Sachdev, Perminder

“…A previous companion paper to this report (Valenzuela and Sachdev, Psychological Medicine 2006, 36, 441-454) suggests a link between behavioural brain reserve…”
Get more information

Cognitive dysfunction in naturally occurring canine idiopathic epilepsy by Packer, Rowena M A, McGreevy, Paul D, Salvin, Hannah E, Valenzuela, Michael J, Chaplin, Chloe M, Volk, Holger A

“…Globally, epilepsy is a common serious brain disorder. In addition to seizure activity, epilepsy is associated with cognitive impairments including static…”
Get full text

Brain reserve and dementia: a systematic review by Valenzuela, Michael J, Sachdev, Perminder

“…Behavioural brain reserve is a property of the central nervous system related to sustained and complex mental activity which can lead to differential…”
Get more information

Lifespan mental activity predicts diminished rate of hippocampal atrophy by Valenzuela, Michael J, Sachdev, Perminder, Wen, Wei, Chen, Xiaohua, Brodaty, Henry

“…Epidemiological studies suggest that complex mental activity may reduce the risk for dementia, however an underlying mechanism remains unclear. Our objective…”
Get full text

Assessment of complex mental activity across the lifespan: development of the Lifetime of Experiences Questionnaire (LEQ) by Valenzuela, Michael J, Sachdev, Perminder

“…Brain reserve is a property of the central nervous system related to complex mental activity which may mediate the course and clinical expression of brain…”
Get more information

Hippocampal plasticity underpins long-term cognitive gains from resistance exercise in MCI by Broadhouse, Kathryn M., Singh, Maria Fiatarone, Suo, Chao, Gates, Nicola, Wen, Wei, Brodaty, Henry, Jain, Nidhi, Wilson, Guy C., Meiklejohn, Jacinda, Singh, Nalin, Baune, Bernhard T., Baker, Michael, Foroughi, Nasim, Wang, Yi, Kochan, Nicole, Ashton, Kevin, Brown, Matt, Li, Zhixiu, Mavros, Yorgi, Sachdev, Perminder S., Valenzuela, Michael J.

“…•Progressive resistance exercise leads to long-term cognitive benefits in MCI.•Resistance exercise slows post-training CA1, subiculum and dentate…”
Get full text

Memory Performance Correlates of Hippocampal Subfield Volume in Mild Cognitive Impairment Subtype by Broadhouse, Kathryn M, Mowszowski, Loren, Duffy, Shantel, Leung, Isabella, Cross, Nathan, Valenzuela, Michael J, Naismith, Sharon L

“…The increased understanding that neuropathology begins decades before symptom onset, has led to the conceptualization and widespread utilization of Mild…”
Get full text

Supervisory experience at work is linked to low rate of hippocampal atrophy in late life by Suo, Chao, León, Irene, Brodaty, Henry, Trollor, Julian, Wen, Wei, Sachdev, Perminder, Valenzuela, Michael J.

“…Cultivation of an active cognitive lifestyle, including diverse and challenging educational, occupational and cognitively-loaded leisure activities may be…”
Get full text

Multiple Biological Pathways Link Cognitive Lifestyle to Protection from Dementia by Valenzuela, Michael J, Matthews, Fiona E, Brayne, Carol, Ince, Paul, Halliday, Glenda, Kril, Jillian J, Dalton, Marshall A, Richardson, Kathryn, Forster, Gill, Sachdev, Perminder S

“…Background An active cognitive lifestyle is linked to diminished dementia risk, but the underlying mechanisms are poorly understood. Potential mechanisms…”
Get full text

Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five by Marioni, Riccardo E, Valenzuela, Michael J, van den Hout, Ardo, Brayne, Carol, Matthews, Fiona E

“…Three factors commonly used as measures of cognitive lifestyle are education, occupation, and social engagement. This study determined the relative importance…”
Get full text

Under diagnosis of canine cognitive dysfunction: A cross-sectional survey of older companion dogs by Salvin, Hannah E., McGreevy, Paul D., Sachdev, Perminder S., Valenzuela, Michael J.

“…Canine cognitive dysfunction (CCD) is a neurobehavioural syndrome affecting aged dogs. Using a large cross-sectional epidemiological study of older dogs, this…”
Get full text

Computerised cognitive training to improve cognition including delirium following coronary artery bypass grafting surgery: protocol for a blinded randomised controlled trial by Greaves, Danielle, Psaltis, Peter J, Lampit, Amit, Davis, Daniel H J, Smith, Ashleigh E, Bourke, Alice, Worthington, Michael G, Valenzuela, Michael J, Keage, Hannah A D

“…IntroductionCoronary artery bypass grafting (CABG) surgery is known to improve vascular function and cardiac-related mortality rates; however, it is associated…”
Get full text

Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke - the Sydney Stroke Study by Brodaty, Henry, Sachdev, Perminder S, Withall, Adrienne, Altendorf, Annette, Valenzuela, Michael J, Lorentz, Lisa

“…The frequency and clinical, neuropsychological and neuroimaging correlates of apathy in patients who have had a stroke are inadequately defined. A total of 167…”
Get more information

Complex mental activity and the aging brain: Molecular, cellular and cortical network mechanisms by Valenzuela, Michael J, Breakspear, Michael, Sachdev, Perminder

“…Abstract There is strong evidence to suggest that high levels of complex mental activity can improve clinical outcome from brain injury. What are the…”
Get full text

Simulation of Neuronal Death and Network Recovery in a Computational Model of Distributed Cortical Activity by Rubinov, Mikail, M.B.B.S, McIntosh, Anthony R., Ph.D, Valenzuela, Michael J., B.Sc. Hons, M.B.B.S. Hons, Ph.D, Breakspear, Michael, M.B.B.S., Ph.D

“…Objectives The authors utilize a model of activity-dependent neuronal plasticity to study the interplay between synaptogenesis, neuronal death, and…”
Get full text

Memory training alters hippocampal neurochemistry in healthy elderly by VALENZUELA, Michael J, JONES, Megan, WEI WEN, RAE, Caroline, GRAHAM, Scott, SHNIER, Ronald, SACHDEV, Perminder

“…Accumulating epidemiological evidence supports the notion of brain reserve, but there has been no investigation of neurobiological change associated with brief…”
Get full text

Cognitive and social lifestyle: links with neuropathology and cognition in late life by Bennett, David A., Arnold, Steven E., Valenzuela, Michael J., Brayne, Carol, Schneider, Julie A.

“…Many studies report an association of cognitive and social experiential factors and related traits with dementia risk. Further, many clinical-pathologic…”
Get full text

Exergame and cognitive training for preventing falls in community-dwelling older people: a randomized controlled trial by Sturnieks, Daina L., Hicks, Cameron, Smith, Natassia, Ratanapongleka, Mayna, Menant, Jasmine, Turner, Jessica, Lo, Joanne, Chaplin, Carly, Garcia, Jaime, Valenzuela, Michael J., Delbaere, Kim, Herbert, Robert D., Sherrington, Catherine, Toson, Barbara, Lord, Stephen R.

“…Exergame training, in which video games are used to promote exercise, can be tailored to address cognitive and physical risk factors for falls and is a…”
Get full text

Lecanemab in Early Alzheimer’s Disease by Zeng, Bing-Syuan, Tseng, Ping-Tao, Liang, Chih-Sung, Valenzuela, Michael J., Pascual-Leone, Alvaro, Pomara, Nunzio, Imbimbo, Bruno P., Brenman, Jay E., van Dyck, Christopher H., Sabbagh, Marwan, Cohen, Sharon

“…To the Editor: In the phase 3 Clarity AD trial by van Dyck et al. (Jan. 5 issue), 1 the primary end point was the change from baseline to 18 months in the…”
Get full text

Age-Specific Effects of Voluntary Exercise on Memory and the Older Brain by Siette, Joyce, Westbrook, R. Frederick, Cotman, Carl, Sidhu, Kuldip, Zhu, Wanlin, Sachdev, Perminder, Valenzuela, Michael J

“…Background Physical exercise in early adulthood and mid-life improves cognitive function and enhances brain plasticity, but the effects of commencing exercise…”
Get full text