Search Results - "Valenzuela, G"

What’s behind a sand fly bite? The profound effect of sand fly saliva on host hemostasis, inflammation and immunity by Abdeladhim, Maha, Kamhawi, Shaden, Valenzuela, Jesus G.

“…•Role of saliva in host hemostasis.•Role of saliva in host inflammation and immunity.•Transcriptomes of sand fly salivary glands.•Sand fly salivary proteins as…”
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Mosquito Saliva: The Hope for a Universal Arbovirus Vaccine? by Manning, Jessica E, Morens, David M, Kamhawi, Shaden, Valenzuela, Jesus G, Memoli, Matthew

“…Arthropod-borne viruses (arboviruses) are taxonomically diverse causes of significant morbidity and mortality. In recent decades, important mosquito-borne…”
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A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing by Zhang, Wen-Wei, Karmakar, Subir, Gannavaram, Sreenivas, Dey, Ranadhir, Lypaczewski, Patrick, Ismail, Nevien, Siddiqui, Abid, Simonyan, Vahan, Oliveira, Fabiano, Coutinho-Abreu, Iliano V., DeSouza-Vieira, Thiago, Meneses, Claudio, Oristian, James, Serafim, Tiago D., Musa, Abu, Nakamura, Risa, Saljoughian, Noushin, Volpedo, Greta, Satoskar, Monika, Satoskar, Sanika, Dagur, Pradeep K., McCoy, J. Philip, Kamhawi, Shaden, Valenzuela, Jesus G., Hamano, Shinjiro, Satoskar, Abhay R., Matlashewski, Greg, Nakhasi, Hira L.

“…Leishmaniasis is a neglected tropical disease caused by Leishmania protozoa transmitted by infected sand flies. Vaccination through leishmanization with live…”
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Food Selectivity and Its Implications Associated with Gastrointestinal Disorders in Children with Autism Spectrum Disorders by Valenzuela-Zamora, Angel F., Ramírez-Valenzuela, David G., Ramos-Jiménez, Arnulfo

“…Food selectivity (FS) in children with autism spectrum disorders (ASD) is common, and its impact on a nutritional level is known. However, the etiology of…”
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A Circadian Clock Entrained by Melatonin Is Ticking in the Rat Fetal Adrenal by Torres-Farfan, C, Mendez, N, Abarzua-Catalan, L, Vilches, N, Valenzuela, G. J, Seron-Ferre, M

“…The rat fetal adrenal contains an autonomous circadian clock, potentially regulated by maternal melatonin. The adrenal gland in the adult is a peripheral…”
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Successful use of baricitinib in the treatment of refractory rheumatoid arthritis‐associated Sweet syndrome by Nousari, Y., Wu, B. C., Valenzuela, G.

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Lundep, a sand fly salivary endonuclease increases Leishmania parasite survival in neutrophils and inhibits XIIa contact activation in human plasma by Chagas, Andrezza C, Oliveira, Fabiano, Debrabant, Alain, Valenzuela, Jesus G, Ribeiro, José M C, Calvo, Eric

“…Neutrophils are the host's first line of defense against infections, and their extracellular traps (NET) were recently shown to kill Leishmania parasites. Here…”
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Impact of vector biology research on old and emerging neglected tropical diseases by Valenzuela, Jesus G, Aksoy, Serap

“…About the Authors: Jesus G. Valenzuela * E-mail: jvalenzuela@niaid.nih.gov (JGV); serap.aksoy@yale.edu (SA) Affiliation: Vector Molecular Biology Section,…”
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Leishmania infection induces a limited differential gene expression in the sand fly midgut by Coutinho-Abreu, Iliano V, Serafim, Tiago Donatelli, Meneses, Claudio, Kamhawi, Shaden, Oliveira, Fabiano, Valenzuela, Jesus G

“…Sand flies are the vectors of Leishmania parasites. To develop in the sand fly midgut, Leishmania multiplies and undergoes various stage differentiations…”
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Payload Estimation in AC Electric Mining Shovels Using Drive Signals by Valenzuela G, Matias, Valenzuela, M. Anibal

“…Shovels play a key role in surface mining operations. Keeping the shovel payload inside the limits defined by manufacturers will reduce mechanical components…”
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Acquired Nonpigmented Vitreous Cyst Associated With Regressed Diabetic Neovascularization by Garcia-Davidson, Diego, Wyhinny, George J, Valenzuela, Enrique G

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Two familial cases of infantile epileptic spasms syndrome associated with UDP-glucose-6-dehydrogenase deficiency by Suyo, C, Reyes Valenzuela, G, Melgarejo, S, Loos, M, Juanes, M, Touzon, M S, Angarita, G, Mesa, M, Alonso, C, Caraballo, R

“…Developmental and epileptic encephalopathies (DEEs) are severe forms of epilepsy characterized by seizure onset in infancy or childhood. The seizures are…”
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A sand fly salivary protein acts as a neutrophil chemoattractant by Guimaraes-Costa, Anderson B., Shannon, John P., Waclawiak, Ingrid, Oliveira, Jullyanna, Meneses, Claudio, de Castro, Waldione, Wen, Xi, Brzostowski, Joseph, Serafim, Tiago D., Andersen, John F., Hickman, Heather D., Kamhawi, Shaden, Valenzuela, Jesus G., Oliveira, Fabiano

“…Apart from bacterial formyl peptides or viral chemokine mimicry, a non-vertebrate or insect protein that directly attracts mammalian innate cells such as…”
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Correction: Salivary Antigen SP32 Is the Immunodominant Target of the Antibody Response to Phlebotomus papatasi Bites in Humans by Marzouki, Soumaya, Abdeladhim, Maha, Abdessalem, Chaouki Ben, Oliveira, Fabiano, Ferjani, Beya, Gilmore, Dana, Louzir, Hechmi, Valenzuela, Jesus G, Ahmed, Mélika Ben

“…[This corrects the article DOI: 10.1371/journal.pntd.0001911.]…”
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Immunity to LuloHya and Lundep, the salivary spreading factors from Lutzomyia longipalpis, protects against Leishmania major infection by Martin-Martin, Ines, Chagas, Andrezza Campos, Guimaraes-Costa, Anderson B, Amo, Laura, Oliveira, Fabiano, Moore, Ian N, DeSouza-Vieira, Thiago S, Sanchez, Elda E, Suntravat, Montamas, Valenzuela, Jesus G, Ribeiro, Jose M C, Calvo, Eric

“…Salivary components from disease vectors help arthropods to acquire blood and have been shown to enhance pathogen transmission in different model systems. Here…”
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Evaluation of cutaneous immune response in a controlled human in vivo model of mosquito bites by Guerrero, David, Vo, Hoa Thi My, Lon, Chanthap, Bohl, Jennifer A., Nhik, Sreynik, Chea, Sophana, Man, Somnang, Sreng, Sokunthea, Pacheco, Andrea R., Ly, Sokna, Sath, Rathanak, Lay, Sokchea, Missé, Dorothée, Huy, Rekol, Leang, Rithea, Kry, Hok, Valenzuela, Jesus G., Oliveira, Fabiano, Cantaert, Tineke, Manning, Jessica E.

“…Mosquito-borne viruses are a growing global threat. Initial viral inoculation occurs in the skin via the mosquito ‘bite’, eliciting immune responses that shape…”
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COVID-19 IMPACT ON HUMAN PAPILLOMAVIRUS IMMUNIZATION PROGRAM IN PERU: MODELLING TIME AND CATCH-UP RATES TO CLOSE THE IMMUNIZATION GAP by Parellada, C., Felsher, M., Valenzuela, G., Flores, C., Farias, L.E., Saxena, K.

“…Between 2020 and 2021, the school-based human papillomavirus (HPV) vaccination program was temporarily interrupted in Peru due to the COVID-19 pandemic. While…”
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Vaccines to combat the neglected tropical diseases by Bethony, Jeffrey M., Cole, Rhea N., Guo, Xiaoti, Kamhawi, Shaden, Lightowlers, Marshall W., Loukas, Alex, Petri, William, Reed, Steven, Valenzuela, Jesus G., Hotez, Peter J.

“…The neglected tropical diseases (NTDs) represent a group of parasitic and related infectious diseases such as amebiasis, Chagas disease, cysticercosis,…”
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A sand fly salivary protein vaccine shows efficacy against vector-transmitted cutaneous leishmaniasis in nonhuman primates by Oliveira, Fabiano, Rowton, Edgar, Aslan, Hamide, Gomes, Regis, Castrovinci, Philip A, Alvarenga, Patricia H, Abdeladhim, Maha, Teixeira, Clarissa, Meneses, Claudio, Kleeman, Lindsey T, Guimarães-Costa, Anderson B, Rowland, Tobin E, Gilmore, Dana, Doumbia, Seydou, Reed, Steven G, Lawyer, Phillip G, Andersen, John F, Kamhawi, Shaden, Valenzuela, Jesus G

“…Currently, there are no commercially available human vaccines against leishmaniasis. In rodents, cellular immunity to salivary proteins of sand fly vectors is…”
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From Insect Bites to a Skin Autoimmune Disease: A Conceivable Pathway to Endemic Pemphigus Foliaceus by Li, Ning, Aoki, Valeria, Liu, Zhi, Prisayanh, Phillip, Valenzuela, Jesus G, Diaz, Luis A

“…In the endemic variants of pemphigus foliaceus (PF), in Brazil and Tunisia, patients generate pathogenic IgG4 anti-desmoglein 1 autoantibodies. Additionally,…”
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