Search Results - "Valenzuela, Carlos Fernando"
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Resistance of Postnatal Hippocampal Neurogenesis to Alcohol Toxicity in a Third Trimester‐Equivalent Mouse Model of Gestational Alcohol Exposure
Published in Alcoholism, clinical and experimental research (01-12-2019)“…Background The adult hippocampal dentate is comprised of both developmentally generated dentate granule cells (dDGCs) and adult‐generated dentate granule cells…”
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2
Prenatal ethanol exposure persistently impairs NMDA receptor-dependent activation of extracellular signal-regulated kinase in the mouse dentate gyrus
Published in Journal of neurochemistry (01-06-2009)“…The dentate gyrus (DG) is the central input region to the hippocampus and is known to play an important role in learning and memory. Previous studies have…”
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3
Acute ethanol exposure inhibits silencing of cerebellar Golgi cell firing induced by granule cell axon input
Published in Frontiers in integrative neuroscience (06-02-2014)“…Golgi cells (GoCs) are specialized interneurons that provide inhibitory input to granule cells in the cerebellar cortex. GoCs are pacemaker neurons that…”
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4
Moderate Alcohol Exposure during the Rat Equivalent to the Third Trimester of Human Pregnancy Alters Regulation of GABAA Receptor-Mediated Synaptic Transmission by Dopamine in the Basolateral Amygdala
Published in Frontiers in pediatrics (27-05-2014)“…Fetal ethanol (EtOH) exposure leads to a range of neurobehavioral alterations, including deficits in emotional processing. The basolateral amygdala (BLA) plays…”
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5
Bestrophin1 Channels are Insensitive to Ethanol and Do not Mediate Tonic GABAergic Currents in Cerebellar Granule Cells
Published in Frontiers in neuroscience (01-01-2012)“…The granule cell layer of the cerebellum functions in spatio-temporal encoding of information. Granule cells (GCs) are tonically inhibited by spillover of GABA…”
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6
Persistent myelin abnormalities in a third trimester‐equivalent mouse model of fetal alcohol spectrum disorder
Published in Alcoholism, clinical and experimental research (01-01-2022)“…Background Abnormal diffusion within white matter (WM) tracts has been linked to cognitive impairment in children with fetal alcohol spectrum disorder. Whether…”
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Platelet-derived Growth Factor Receptor-induced Feed-forward Inhibition of Excitatory Transmission between Hippocampal Pyramidal Neurons
Published in The Journal of biological chemistry (22-10-1999)“…Growth factor receptors provide a major mechanism for the activation of the nonreceptor tyrosine kinase c-Src, and this kinase in turn up-regulates the…”
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Acute oligodendrocyte loss with persistent white matter injury in a third trimester equivalent mouse model of fetal alcohol spectrum disorder
Published in Glia (01-08-2017)“…Alcohol exposure during central nervous system (CNS) development can lead to fetal alcohol spectrum disorder (FASD). Human imaging studies have revealed…”
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Ethanol exposure during the third trimester equivalent does not affect GABAA or AMPA receptor-mediated spontaneous synaptic transmission in rat CA3 pyramidal neurons
Published in Journal of negative results in biomedicine (02-12-2015)“…Ethanol exposure during the rodent equivalent to the 3(rd) trimester of human pregnancy (i.e., first 1-2 weeks of neonatal life) has been shown to produce…”
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10
AMPAR-mediated synaptic transmission in the CA1 hippocampal region of neonatal rats: unexpected resistance to repeated ethanol exposure
Published in Alcohol (Fayetteville, N.Y.) (01-12-2009)“…Abstract α-Amino-3-hydroxyl-5-methyl-4-isoxazole-propionate glutamatergic receptors (AMPAR) mediate most of the fast excitatory synaptic transmission in mature…”
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11
Moderate alcohol exposure during the rat equivalent to the third trimester of human pregnancy alters dopamine regulation of GABAA receptor-mediated transmission in the basolateral amygdala
Published in Frontiers in pediatrics (01-05-2014)“…Fetal ethanol (EtOH) exposure leads to a range of neurobehavioral alterations, including deficits in emotional processing. The basolateral amygdala (BLA) plays…”
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Journal Article -
12
The nicotinic acetylcholine receptor: Ligand modulation and binding site localization
Published 01-01-1993“…This dissertation examines ligand interactions with the Torpedo nicotinic acetylcholine receptor (AcChR). The interaction of the AcChR with various competitive…”
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Dissertation