Search Results - "Valentine, Vincent G"

Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis by Donahoe, Michael, Valentine, Vincent G, Chien, Nydia, Gibson, Kevin F, Raval, Jay S, Saul, Melissa, Xue, Jianmin, Zhang, Yingze, Duncan, Steven R

“…Severe acute exacerbations (AE) of idiopathic pulmonary fibrosis (IPF) are medically untreatable and often fatal within days. Recent evidence suggests…”
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Decrements of body mass index are associated with poor outcomes of idiopathic pulmonary fibrosis patients by Kulkarni, Tejaswini, Yuan, Kaiyu, Tran-Nguyen, Thi K, Kim, Young-Il, de Andrade, Joao A, Luckhardt, Tracy, Valentine, Vincent G, Kass, Daniel J, Duncan, Steven R

“…The processes that result in progression of idiopathic pulmonary fibrosis (IPF) remain enigmatic. Moreover, the course of this disease can be highly variable…”
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Correlates of survival after autoantibody reduction therapy for acute IPF exacerbations by Kulkarni, Tejaswini, Valentine, Vincent G, Fei, Fei, Tran-Nguyen, Thi K, Quesada-Arias, Luisa D, Mkorombindo, Takudzwa, Pham, Huy P, Simmons, Sierra C, Dsouza, Kevin G, Luckhardt, Tracy, Duncan, Steven R

“…No medical treatment has proven efficacy for acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF), and this syndrome has a very high mortality. Based…”
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CD28 down-regulation on circulating CD4 T-cells is associated with poor prognoses of patients with idiopathic pulmonary fibrosis by Gilani, Syed R, Vuga, Louis J, Lindell, Kathleen O, Gibson, Kevin F, Xue, Jianmin, Kaminski, Naftali, Valentine, Vincent G, Lindsay, Emily K, George, M Patricia, Steele, Chad, Duncan, Steven R

“…Although the etiology of idiopathic pulmonary fibrosis (IPF) remains perplexing, adaptive immune activation is evident among many afflicted patients. Repeated…”
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The role of chloride anion and CFTR in killing of Pseudomonas aeruginosa by normal and CF neutrophils by Painter, Richard G., Bonvillain, Ryan W., Valentine, Vincent G., Lombard, Gisele A., LaPlace, Stephanie G., Nauseef, William M., Wang, Guoshun

“…Chloride anion is essential for myeloperoxidase (MPO) to produce hypochlorous acid (HOCl) in polymorphonuclear neutrophils (PMNs). To define whether chloride…”
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CFTR-mediated halide transport in phagosomes of human neutrophils by Painter, Richard G., Marrero, Luis, Lombard, Gisele A., Valentine, Vincent G., Nauseef, William M., Wang, Guoshun

“…CFTR transports chloride anions necessary for HOCl production and optimal microbicidal activity in human neutrophil phagosomes. Chloride serves as a critical…”
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Cellular and Humoral Autoreactivity in Idiopathic Pulmonary Fibrosis by Feghali-Bostwick, Carol A, Tsai, Christopher G, Valentine, Vincent G, Kantrow, Stephen, Stoner, Michael W, Pilewski, Joseph M, Gadgil, Aneal, George, M. Patricia, Gibson, Kevin F, Choi, Augustine M. K, Kaminski, Naftali, Zhang, Yingze, Duncan, Steven R

“…Idiopathic pulmonary fibrosis (IPF) is a morbid, refractory lung disorder with an unknown pathogenesis. To investigate potential adaptive immune mechanisms in…”
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Reliability of diagnostic criteria for bronchiolitis obliterans syndrome after lung transplantation: A survey by Kapila, Atul, MD, Baz, Maher A., MD, Valentine, Vincent G., MD, Bhorade, Sangeeta M., MD

“…Background Long-term outcomes after lung transplantation are limited due to chronic lung allograft dysfunction (CLAD). Bronchiolitis obliterans syndrome (BOS)…”
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Interobserver Variability in Grading Transbronchial Lung Biopsy Specimens After Lung Transplantation by Bhorade, Sangeeta M., MD, FCCP, Husain, Aliya N., MD, Liao, Chuanhong, MS, Li, Lee Chuan, BA, Ahya, Vivek N., MD, Baz, Maher A., MD, Valentine, Vincent G., MD, FCCP, Love, Robert B., MD, Seethamraju, Harish, MD, Alex, Charles G., MD, FCCP, Bag, Remzi, MD, FCCP, DeOliveira, Nilto C., MD, Vigneswaran, Wickii T., MD, Garrity, Edward R., MD, FCCP, Arcasoy, Selim M., MD, FCCP

“…Abstract Background Acute rejection remains a major source of morbidity after lung transplantation. Given the importance of this diagnosis, an international…”
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Adult Stem Cells from Bone Marrow Stroma Differentiate into Airway Epithelial Cells: Potential Therapy for Cystic Fibrosis by Wang, Guoshun, Bunnell, Bruce A., Painter, Richard G., Quiniones, Blesilda C., Tom, Susan, Lanson, Nicholas A., Spees, Jeffrey L., Bertucci, Donna, Peister, Alexandra, Weiss, Daniel J., Valentine, Vincent G., Prockop, Darwin J., Kolls, Jay K.

“…Cystic fibrosis (CF), the most prevalent, fatal genetic disorder in the Caucasian population, is caused by mutations of CF transmembrane conductance regulator…”
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Effect of Etiology and Timing of Respiratory Tract Infections on Development of Bronchiolitis Obliterans Syndrome by Valentine, Vincent G., MD, FACP, Gupta, Meera R., MD, Walker, James E., MD, Seoane, Leonardo, MD, Bonvillain, Ryan W., BS, Lombard, Gisele A., RNC, BSN, Weill, David, MD, Dhillon, Gundeep S., MD

“…Background Among the many potential risk factors influencing the development of bronchiolitis obliterans syndrome (BOS), acute cellular rejection is the most…”
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Decreased incidence of cytomegalovirus infection with sirolimus in a post hoc randomized, multicenter study in lung transplantation by Ghassemieh, Bijan, MD, Ahya, Vivek N., MD, Baz, Maher A., MD, Valentine, Vincent G., MD, Arcasoy, Selim M., MD, Love, Robert B., MD, Seethamraju, Harish, MD, Alex, Charles G., MD, Bag, Remzi, MD, DeOliveira, Nilto C., MD, Vigneswaran, Wickii T., MD, Charbeneau, Jeff, MS, Garrity, Edward R., MD, Bhorade, Sangeeta M., MD

“…Background Cytomegalovirus (CMV) is the most common opportunistic infection in lung transplantation. A recent multicenter, randomized trial (the AIRSAC study)…”
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Correction: Autoantibody-Targeted Treatments for Acute Exacerbations of Idiopathic Pulmonary Fibrosis by Donahoe, Michael, Valentine, Vincent G, Chien, Nydia, Gibson, Kevin F, Raval, Jay S, Saul, Melissa, Xue, Jianmin, Zhang, Yingze, Duncan, Steven R

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Single-institution Study Evaluating the Utility of Surveillance Bronchoscopy After Lung Transplantation by Valentine, Vincent G., MD, FACP, Gupta, Meera R., MD, Weill, David, MD, Lombard, Gisele A., RNC, BSN, LaPlace, Stephanie G., RNC, BSN, Seoane, Leonardo, MD, Taylor, David E., MD, Dhillon, Gundeep S., MD

“…Background Many lung transplant physicians advocate surveillance bronchoscopy with transbronchial lung biopsy and bronchoalveolar lavage (TBB/BAL) to monitor…”
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Increased risk of venous thromboembolism with a sirolimus-based immunosuppression regimen in lung transplantation by Ahya, Vivek N., MD, McShane, Pamela J., MD, Baz, Maher A., MD, Valentine, Vincent G., MD, Arcasoy, Selim M., MD, Love, Robert B., MD, Seethamraju, Harish, MD, Garrity, Edward, MD, Alex, Charles G., MD, Bag, Remzi, MD, DeOliveira, Nilto C., MD, Vigneswaran, Wickii T., MD, Charbeneau, Jeff, MS, Krishnan, Jerry A., MD, PhD, Durazo-Arvizu, Ramon, PhD, Norwick, Lourdes, BSN, RN, Bhorade, Sangeeta, MD

“…Background Sirolimus (rapamycin) is a potent anti-proliferative agent with immunosuppressive properties that is increasingly being used in solid-organ and…”
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Post-operative Infections in Cystic Fibrosis and Non–Cystic Fibrosis Patients After Lung Transplantation by Bonvillain, Ryan W., BS, Valentine, Vincent G., MD, Lombard, Gisele, RN, LaPlace, Stephanie, RN, Dhillon, Gundeep, MD, Wang, Guoshun, DVM, PhD

“…Background Cystic fibrosis (CF) lung disease is the major cause of mortality in CF patients. Lung transplantation remains a valid therapeutic option. It is…”
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Ganciclovir for Cytomegalovirus: a Call for Indefinite Prophylaxis in Lung Transplantation by Valentine, Vincent G., MD, FACP, Weill, David, MD, Gupta, Meera R., MD, Raper, Brad, MD, LaPlace, Stephanie G., RNC, BSN, Lombard, Gisele A., RNC, BSN, Bonvillain, Ryan W., BS, Taylor, David E., MD, Dhillon, Gundeep S., MD

“…Background Universal ganciclovir (GCV) prophylaxis is a strategy aimed at reducing cytomegalovirus (CMV) infection and delaying the development of…”
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Infections in Lung Allograft Recipients: Ganciclovir Era by Valentine, Vincent G., MD, FCCP, FACP, Bonvillain, Ryan W., BS, Gupta, Meera R., MD, Lombard, Gisele A., RN, CCTC, LaPlace, Stephanie G., RNC, CCTC, Dhillon, Gundeep S., MD, Wang, Guoshun, DVM, PhD

“…Background Infections are common after lung transplantation. This report analyzes infections and associated pathogens identified in 202 lung transplant…”
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Fortification of Preservation Solution With Nitroprusside Does Not Alter Lung Allograft Survival in Clinical Human Lung Transplantation by Boys, Joshua A, Bowdish, Michael E, Subramanyan, Ram Kumar, Shemanski, Kimberly A, Dhillon, Gundeep S, Toda, Koichi, Perrillo, Johanna, Seoane, Leonardo, Bates, Michael J, Parrino, P Eugene, Kooperkamp, Hannah, Valentine, Vincent G, Emory, W Brooks, Ochsner, John L, McFadden, P Michael

“…Nitric oxide improves gas exchange following primary lung allograft dysfunction. Nitroprusside, a potent nitric oxide donor, has reduced reperfusion injury and…”
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CFTR targeting during activation of human neutrophils by Ng, Hang Pong, Valentine, Vincent G., Wang, Guoshun

“…Activated neutrophils regulate CFTR distribution by targeting this chloride channel to the subcellular sites of activation. Cystic fibrosis transmembrane…”
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