Search Results - "Valentin, P"

Enterosorption may contribute to the reactivation of anticancer immunity and be an effective approach to tumor growth control by Shichkin, Valentin P

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Key Factors for Thymic Function and Development by Shichkin, Valentin P., Antica, Mariastefania

“…The thymus is the organ responsible for T cell development and the formation of the adaptive immunity function. Its multicellular environment consists mainly…”
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Distinct Migratory Properties of M1, M2, and Resident Macrophages Are Regulated by αDβ2 and αMβ2 Integrin-Mediated Adhesion by Cui, Kui, Ardell, Christopher L., Podolnikova, Nataly P., Yakubenko, Valentin P.

“…Chronic inflammation is essential mechanism during the development of cardiovascular and metabolic diseases. The outcome of diseases depends on the balance…”
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Nanozeolites:  Synthesis, Crystallization Mechanism, and Applications by Tosheva, Lubomira, Valtchev, Valentin P

“…This review focuses on the synthesis, crystallization mechanism, and application of colloidal zeolites. The synthesis formulations and features of different…”
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Divergent projections of the prelimbic cortex bidirectionally regulate active avoidance by Diehl, Maria M, Iravedra-Garcia, Jorge M, Morán-Sierra, Jonathan, Rojas-Bowe, Gabriel, Gonzalez-Diaz, Fabiola N, Valentín-Valentín, Viviana P, Quirk, Gregory J

“…The prefrontal cortex (PFC) integrates incoming information to guide our actions. When motivation for food-seeking competes with avoidance of danger, the PFC…”
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IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages by Bhattacharjee, Ashish, Shukla, Meenakshi, Yakubenko, Valentin P., Mulya, Anny, Kundu, Suman, Cathcart, Martha K.

“…Monocytes/macrophages are innate immune cells that play a crucial role in the resolution of inflammation. In the presence of the Th2 cytokines interleukin-4…”
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Structural mechanism of integrin inactivation by filamin by Liu, Jianmin, Das, Mitali, Yang, Jun, Ithychanda, Sujay Subbayya, Yakubenko, Valentin P, Plow, Edward F, Qin, Jun

“…The integrin inhibitor filamin competes with activators for integrin binding, but an NMR structural analysis now reveals that filamin also functions by…”
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Neuroimmune nexus in the pathophysiology and therapy of inflammatory disorders: Role of α7 nicotinic acetylcholine receptors by Keever, Kasey R., Yakubenko, Valentin P., Hoover, Donald B.

“…The α7-nicotinic acetylcholine receptor (α7nAChR) is a key protein in the cholinergic anti-inflammatory pathway (CAP) that links the nervous and immune…”
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Multi-Arm Star-Shaped Glycopolymers with Precisely Controlled Core Size and Arm Length by Monaco, Alessandra, Beyer, Valentin P, Napier, Richard, Becer, C. Remzi

“…Star-shaped glycopolymers provide very high binding activities toward lectins. However, a straightforward synthesis method for the preparation of multi-arm…”
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Brush Copolymers from 2‑Oxazoline and Acrylic Monomers via an Inimer Approach by Beyer, Valentin P, Cattoz, Beatrice, Strong, Anthony, Schwarz, Andrew, Becer, C. Remzi

“…Brush-shaped macromolecular architectures provide unique material properties because of their dense branched structures. However, there are major challenges in…”
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Bottlebrush Glycopolymers from 2-Oxazolines and Acrylamides for Targeting Dendritic Cell-Specific Intercellular Adhesion Molecule-3-Grabbing Nonintegrin and Mannose-Binding Lectin by Beyer, Valentin P, Monaco, Alessandra, Napier, Richard, Yilmaz, Gokhan, Becer, C Remzi

“…Lectins are omnipresent carbohydrate binding proteins that are involved in a multitude of biological processes. Unearthing their binding properties is a…”
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On the relationship between block of the cardiac Na+ channel and drug‐induced prolongation of the QRS complex by Harmer, AR, Valentin, J‐P, Pollard, CE

“…BACKGROUND AND PURPOSE Inhibition of the human cardiac Na+ channel (hNav1.5) can prolong the QRS complex and has been associated with increased mortality in…”
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Fluorinated Polymers via Para‐Fluoro‐Thiol and Thiol‐Bromo Click Step Growth Polymerization by Zhao, Tieshuai, Beyer, Valentin P., Becer, Caglar Remzi

“…Click reactions are utilized widely to modify chain ends and side groups of polymers while click polymerizations based on step‐growth polymerization of…”
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Analysis of Vibrational Circular Dichroism Spectra of Peptides: A Generalized Coupled Oscillator Approach of a Small Peptide Model Using VCDtools by Koenis, Mark A. J, Visscher, Lucas, Buma, Wybren J, Nicu, Valentin P

“…Vibrational circular dichroism (VCD) is one of the major spectroscopic tools to study peptides. Nevertheless, a full understanding of what determines the signs…”
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Leukocyte integrin Mac-1 (CD11b/CD18, αMβ2, CR3) acts as a functional receptor for platelet factor 4 by Lishko, Valeryi K., Yakubenko, Valentin P., Ugarova, Tatiana P., Podolnikova, Nataly P.

“…Platelet factor 4 (PF4) is one of the most abundant cationic proteins secreted from α-granules of activated platelets. Based on its structure, PF4 was assigned…”
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Determination of the Absolute Configurations Using Exciton Chirality Method for Vibrational Circular Dichroism: Right Answers for the Wrong Reasons? by Covington, Cody L, Nicu, Valentin P, Polavarapu, Prasad L

“…Quantum chemical (QC) predictions of vibrational circular dichroism (VCD) spectra for the keto form of 3-benzoylcamphor and conformationally flexible…”
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Editorial: Thymus function and aging: A focus on thymic epithelial cells by Shichkin, Valentin P., Felli, Maria Pia, Screpanti, Isabella, Antica, Mariastefania

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Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation by Keever, Kasey R, Cui, Kui, Casteel, Jared L, Singh, Sanjay, Hoover, Donald B, Williams, David L, Pavlov, Valentin A, Yakubenko, Valentin P

“…The involvement of the autonomic nervous system in the regulation of inflammation is an emerging concept with significant potential for clinical applications…”
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Biological and pathophysiological roles of end-products of DHA oxidation by Yakubenko, Valentin P., Byzova, Tatiana V.

“…Polyunsaturated fatty acids (PUFA) are known to be present and/or enriched in vegetable and fish oils. Among fatty acids, n-3 PUFA are generally considered to…”
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How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines? by Laverty, HG, Benson, C, Cartwright, EJ, Cross, MJ, Garland, C, Hammond, T, Holloway, C, McMahon, N, Milligan, J, Park, BK, Pirmohamed, M, Pollard, C, Radford, J, Roome, N, Sager, P, Singh, S, Suter, T, Suter, W, Trafford, A, Volders, PGA, Wallis, R, Weaver, R, York, M, Valentin, JP

“…Given that cardiovascular safety liabilities remain a major cause of drug attrition during preclinical and clinical development, adverse drug reactions, and…”
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