Search Results - "Valenti, Giulia"
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Antimicrobial Peptides and Cationic Nanoparticles: A Broad-Spectrum Weapon to Fight Multi-Drug Resistance Not Only in Bacteria
Published in International journal of molecular sciences (29-05-2022)“…In the last few years, antibiotic resistance and, analogously, anticancer drug resistance have increased considerably, becoming one of the main public health…”
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Glutathione in cancer progression and chemoresistance: an update
Published in Redox experimental medicine (01-02-2024)“…Glutathione (GSH) is one of the most important components of the cellular antioxidant system, and it is able to exert several pleiotropic functions influencing…”
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Synthesis of Polystyrene-Based Cationic Nanomaterials with Pro-Oxidant Cytotoxic Activity on Etoposide-Resistant Neuroblastoma Cells
Published in Nanomaterials (Basel, Switzerland) (10-04-2021)“…Drug resistance is a multifactorial phenomenon that limits the action of antibiotics and chemotherapeutics. Therefore, it is essential to develop new…”
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Anti-Survival Effect of SI306 and Its Derivatives on Human Glioblastoma Cells
Published in Pharmaceutics (01-07-2022)“…Glioblastoma (GBM) is the most common adult brain tumor and, although many efforts have been made to find valid therapies, the onset of resistance is the main…”
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Imidazo-Pyrazole-Loaded Palmitic Acid and Polystyrene-Based Nanoparticles: Synthesis, Characterization and Antiproliferative Activity on Chemo-Resistant Human Neuroblastoma Cells
Published in International journal of molecular sciences (01-10-2023)“…Neuroblastoma (NB) is a childhood cancer, commonly treated with drugs, such as etoposide (ETO), whose efficacy is limited by the onset of resistance. Here,…”
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D-α-Tocopherol-Based Micelles for Successful Encapsulation of Retinoic Acid
Published in Pharmaceuticals (Basel, Switzerland) (04-03-2021)“…All- -retinoic acid (ATRA) represents the first-choice treatment for several skin diseases, including epithelial skin cancer and acne. However, ATRA's…”
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Antiproliferative Imidazo-Pyrazole-Based Hydrogel: A Promising Approach for the Development of New Treatments for PLX-Resistant Melanoma
Published in Pharmaceutics (01-10-2023)“…Aiming at developing a dermal formulation against melanoma, the synthesized imidazo-pyrazoles 2-phenyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid…”
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PLX4032 resistance of patient-derived melanoma cells: crucial role of oxidative metabolism
Published in Frontiers in oncology (18-07-2023)“…Malignant melanoma is the most lethal form of skin cancer which shows BRAF mutation in 50% of patients. In this context, the identification of BRAF mutation…”
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PTC596-Induced BMI-1 Inhibition Fights Neuroblastoma Multidrug Resistance by Inducing Ferroptosis
Published in Antioxidants (01-01-2024)“…Neuroblastoma (NB) is a paediatric cancer with noteworthy heterogeneity ranging from spontaneous regression to high-risk forms that are characterised by cancer…”
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PKCα Inhibition as a Strategy to Sensitize Neuroblastoma Stem Cells to Etoposide by Stimulating Ferroptosis
Published in Antioxidants (28-04-2021)“…Cancer stem cells (CSCs) are a limited cell population inside a tumor bulk characterized by high levels of glutathione (GSH), the most important antioxidant…”
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BMI-1 inhibition fights cancer chemoresistance by altering redox homeostasis and inducing lipid peroxidation
Published in Free radical biology & medicine (01-03-2023)Get full text
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Online psychological counselling during lockdown reduces anxiety symptoms and negative affect: Insights from Italian framework
Published in Clinical psychology and psychotherapy (01-01-2022)“…Several studies have shown how COrona VIrus Disease 2019 (COVID‐19) and the consequent isolation and quarantine measures could affect physical and mental…”
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Potential Role of miRNAs in the Acquisition of Chemoresistance in Neuroblastoma
Published in Journal of personalized medicine (07-02-2021)“…Neuroblastoma (NB) accounts for about 8-10% of pediatric cancers, and the main causes of death are the presence of metastases and the acquisition of…”
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