Search Results - "Valentão, Patrícia"

Unearthing of the Antidiabetic Potential of Aqueous Extract of Solanum betaceum Cav. Leaves by Martins, Raquel, Fernandes, Fátima, Valentão, Patrícia

“…Cav., commonly known as tamarillo or Brazilian tomato, belongs to the Solanaceae family. Its fruit is used in traditional medicine and food crops due to its…”
Get full text

Tuning protein folding in lysosomal storage diseases: the chemistry behind pharmacological chaperones by Pereira, David M, Valentão, Patrícia, Andrade, Paula B

“…Misfolding of proteins is the basis of several proteinopathies. Chemical and pharmacological chaperones are small molecules capable of inducing the correct…”
Get full text

Alternative and efficient extraction methods for marine-derived compounds by Grosso, Clara, Valentão, Patrícia, Ferreres, Federico, Andrade, Paula B

“…Marine ecosystems cover more than 70% of the globe's surface. These habitats are occupied by a great diversity of marine organisms that produce highly…”
Get full text

Endoplasmic reticulum stress signaling in cancer and neurodegenerative disorders: Tools and strategies to understand its complexity by da Silva, Daniela Correia, Valentão, Patrícia, Andrade, Paula B., Pereira, David M.

“…[Display omitted] The endoplasmic reticulum (ER) comprises a network of tubules and vesicles that constitutes the largest organelle of the eukaryotic cell…”
Get full text

Antifungal activity of phlorotannins against dermatophytes and yeasts: approaches to the mechanism of action and influence on Candida albicans virulence factor by Lopes, Graciliana, Pinto, Eugénia, Andrade, Paula B, Valentão, Patrícia

“…In the last few decades, fungal infections, particularly nosocomial, increased all around the world. This increment stimulated the search for new antifungal…”
Get full text

Phlorotannins: Towards New Pharmacological Interventions for Diabetes Mellitus Type 2 by Lopes, Graciliana, Andrade, Paula B, Valentão, Patrícia

“…Diabetes mellitus is a group of metabolic disorders characterized by hyperglycaemia, and predicted by the World Health Organization as the expected 7th leading…”
Get full text

Polyphenols from Brown Seaweeds (Ochrophyta, Phaeophyceae): Phlorotannins in the Pursuit of Natural Alternatives to Tackle Neurodegeneration by Barbosa, Mariana, Valentão, Patrícia, Andrade, Paula B

“…Globally, the burden of neurodegenerative disorders continues to rise, and their multifactorial etiology has been regarded as among the most challenging…”
Get full text

Bioactive compounds from macroalgae in the new millennium: implications for neurodegenerative diseases by Barbosa, Mariana, Valentão, Patrícia, Andrade, Paula B

“…Marine environment has proven to be a rich source of structurally diverse and complex compounds exhibiting numerous interesting biological effects. Macroalgae…”
Get full text

Camel Grass Phenolic Compounds: Targeting Inflammation and Neurologically Related Conditions by Lopes, Graciliana, Gomes, Elisabete, Barbosa, Mariana, Bernardo, João, Valentão, Patrícia

“…The use of plants for therapeutic purposes has been supported by growing scientific evidence. This work consisted of (i) characterizing the phenolic compounds…”
Get full text

Valorization of Winemaking By-Products as a Novel Source of Antibacterial Properties: New Strategies to Fight Antibiotic Resistance by Silva, Adriana, Silva, Vanessa, Igrejas, Gilberto, Gaivão, Isabel, Aires, Alfredo, Klibi, Naouel, Enes Dapkevicius, Maria de Lurdes, Valentão, Patrícia, Falco, Virgílio, Poeta, Patrícia

“…The emergence of antibiotic-resistance in bacteria has limited the ability to treat bacterial infections, besides increasing their morbidity and mortality at…”
Get full text

Algae-Based Supplements Claiming Weight Loss Properties: Authenticity Control and Scientific-Based Evidence on Their Effectiveness by Fernandes, Fátima, Martins, Raquel, Barbosa, Mariana, Valentão, Patrícia

“…The worldwide prevalence of obesity impacts more than 600 million adults. Successfully managing weight is effective in reducing the risk of chronic diseases,…”
Get full text

Biologically Active Oxylipins from Enzymatic and Nonenzymatic Routes in Macroalgae by Barbosa, Mariana, Valentão, Patrícia, Andrade, Paula B

“…Marine algae are rich and heterogeneous sources of great chemical diversity, among which oxylipins are a well-recognized class of natural products. Algal…”
Get full text

In silico and in vitro chemometrics, cell toxicity and permeability of naringenin 8-sulphonate and derivatives by Macedo, Tiago, Paiva-Martins, Fátima, Valentão, Patrícia, Pereira, David M

“…Sulphur containing natural compounds are among the most biologically relevant metabolites . Naringenin 8-sulphonate from Sabine was evaluated in a previous…”
Get full text

Insights into Natural Products in Inflammation by Andrade, Paula B, Valentão, Patrícia

Get full text

Red Grape By-Products from the Demarcated Douro Region: Chemical Analysis, Antioxidant Potential and Antimicrobial Activity against Food-Borne Pathogens by Silva, Adriana, Martins, Raquel, Silva, Vanessa, Fernandes, Fátima, Carvalho, Rosa, Aires, Alfredo, Igrejas, Gilberto, Falco, Virgílio, Valentão, Patrícia, Poeta, Patrícia

“…Wine production is one of the most important agricultural activities. The winemaking process generates a considerable volume of different residues…”
Get full text

How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria‐targeted drugs by Pinho, Brígida R, Santos, Miguel M, Fonseca‐Silva, Anabela, Valentão, Patrícia, Andrade, Paula B, Oliveira, Jorge M A

“…Background and Purpose Mitochondria are a drug target in mitochondrial dysfunction diseases and in antiparasitic chemotherapy. While zebrafish is increasingly…”
Get full text

Integrated analysis of COX-2 and iNOS derived inflammatory mediators in LPS-stimulated RAW macrophages pre-exposed to Echium plantagineum L. bee pollen extract by Moita, Eduarda, Gil-Izquierdo, Angel, Sousa, Carla, Ferreres, Federico, Silva, Luís R, Valentão, Patrícia, Domínguez-Perles, Raúl, Baenas, Nieves, Andrade, Paula B

“…Oxidative stress and inflammation play important roles in disease development. This study intended to evaluate the anti-inflammatory and antioxidant potential…”
Get full text

Metabolic profile and biological activities of Lavandula pedunculata subsp. lusitanica (Chaytor) Franco: Studies on the essential oil and polar extracts by Costa, Patrícia, Gonçalves, Sandra, Valentão, Patrícia, Andrade, Paula B., Almeida, Carlos, Nogueira, José M.F., Romano, Anabela

“…•We studied the Lavandula pedunculata subsp. lusitanica metabolic profile.•Oxygen-containing monoterpenes were the main compounds in the essential…”
Get full text

Tomato plant leaves: From by-products to the management of enzymes in chronic diseases by Figueiredo-González, María, Valentão, Patrícia, Andrade, Paula B.

“…[Display omitted] •Tomato leaves from eight selected cultivars studied for the first time.•Tomato leaves are rich mixtures of phenolics, carotenoids and…”
Get full text

A Pipeline for Natural Small Molecule Inhibitors of Endoplasmic Reticulum Stress by Correia da Silva, Daniela, Valentão, Patrícia, Andrade, Paula B., Pereira, David M.

“…The homeostasis of eukaryotic cells is inseverable of that of the endoplasmic reticulum (ER). The main function of this organelle is the synthesis and folding…”
Get full text