Physiological and radio-induced modulations of low-weight globulins in distinct vascular compartments

The main goal was to investigate the profiles of molecular weight globulins lower than albumin in the electrophoresis system in function of the exposition time to gamma radiation. At 72 h post-irradiation, the globulin electrophoretic profiles bellow albumin showed significant radio-induced changes....

Full description

Saved in:

Bibliographic Details
Published in:	Journal of radioanalytical and nuclear chemistry Vol. 318; no. 2; pp. 1317 - 1324
Main Authors:	Lima, Celso Vieira, de Campos, Tarcísio Passos Ribeiro, Valencia, Carlos Julio Montano, Almeida, Iassudara Garcia
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 01-11-2018 Springer Springer Nature B.V
Subjects:	Albumin Blood proteins Chemistry Chemistry and Materials Science Diagnostic Radiology Electrophoresis Gamma rays Gene expression Globulins Hadrons Heavy Ions Inorganic Chemistry Ionizing radiation Kidneys Molecular weight Nuclear Chemistry Nuclear Physics Physical Chemistry Physiology Radio Spleen Rats Electrophoresis Serum protein Globulin Radiation
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	The main goal was to investigate the profiles of molecular weight globulins lower than albumin in the electrophoresis system in function of the exposition time to gamma radiation. At 72 h post-irradiation, the globulin electrophoretic profiles bellow albumin showed significant radio-induced changes. In addition, the vascular system, specifically the inferior vena cava, kidney, spleen, jugular, hepatic, and pulmonary veins presented a physiological compartmental distribution of globulins. The findings pointed out the radio-induced alterations of the serum globulin concentrations as a late event, possibly related to a radio modulation of the genes’ expression.
ISSN:	0236-5731 1588-2780
DOI:	10.1007/s10967-018-6188-3