Search Results - "Valdivielso, Jose M."

Atherosclerosis in Chronic Kidney Disease: More, Less, or Just Different? by Valdivielso, José M, Rodríguez-Puyol, Diego, Pascual, Julio, Barrios, Clara, Bermúdez-López, Marcelino, Sánchez-Niño, Maria Dolores, Pérez-Fernández, María, Ortiz, Alberto

“…Patients with chronic kidney disease (CKD) are at an increased risk of premature mortality, mainly from cardiovascular causes. The association between CKD on…”
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Vitamin D receptor polymorphisms and diseases by Valdivielso, Jose M., Fernandez, Elvira

“…The vitamin D endocrine system is central to the control of bone and calcium homeostasis. Thus, alterations in the vitamin D pathway lead to disturbances in…”
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Independent effects of secondary hyperparathyroidism and hyperphosphataemia on chronic kidney disease progression and cardiovascular events: an analysis from the NEFRONA cohort by Bozic, Milica, Diaz-Tocados, Juan M, Bermudez-Lopez, Marcelino, Forné, Carles, Martinez, Cristina, Fernandez, Elvira, Valdivielso, José M

“…Abstract Background Secondary hyperparathyroidism (SHPT) is a complication of chronic kidney disease (CKD) and is associated with changes in calcium and…”
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SGLT2i for evidence-based cardiorenal protection in diabetic and non-diabetic chronic kidney disease: a comprehensive review by EURECA-m and ERBP working groups of ERA by Mark, Patrick B, Sarafidis, Pantelis, Ekart, Robert, Ferro, Charles J, Balafa, Olga, Fernandez-Fernandez, Beatriz, Herrington, William G, Rossignol, Patrick, Del Vecchio, Lucia, Valdivielso, Jose M, Mallamaci, Francesca, Ortiz, Alberto, Nistor, Ionut, Cozzolino, Mario

“…ABSTRACT Chronic kidney disease (CKD) is a major public health issue affecting an estimated 850 million people globally. The leading causes of CKD is diabetes…”
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Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases by Grande-García, Araceli, Echarri, Asier, de Rooij, Johan, Alderson, Nazilla B, Waterman-Storer, Clare M, Valdivielso, José M, del Pozo, Miguel A

“…Development, angiogenesis, wound healing, and metastasis all involve the movement of cells in response to changes in the extracellular environment. To…”
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The potential of targeting NMDA receptors outside the CNS by Bozic, Milica, Valdivielso, José M

“…NMDA receptor (NMDAR) is an ionotropic glutamate receptor with a high permeability to calcium and a unique feature of controlling numerous calcium-dependent…”
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Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage by Ruiz-Ortega, Marta, Valdivielso, José Manuel, Valentijn, Floris, Morgado-Pascual, Jose Luis, Rodrigues-Diez, Raul, Rayego-Mateos, Sandra, Goldschmeding, Roel

“…Chronic kidney disease (CKD) is characterized by persistent inflammation and progressive fibrosis, ultimately leading to end-stage renal disease. Although many…”
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Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies by Valdivielso, José M., Balafa, Olga, Ekart, Robert, Ferro, Charles J., Mallamaci, Francesca, Mark, Patrick B., Rossignol, Patrick, Sarafidis, Pantelis, Del Vecchio, Lucia, Ortiz, Alberto

“…Despite recent therapeutic advances, chronic kidney disease (CKD) is one of the fastest growing global causes of death. This illustrates limitations of current…”
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Extracellular Vesicles and Renal Fibrosis: An Odyssey toward a New Therapeutic Approach by Kosanović, Maja, Llorente, Alicia, Glamočlija, Sofija, Valdivielso, José M, Bozic, Milica

“…Renal fibrosis is a complex disorder characterized by the destruction of kidney parenchyma. There is currently no cure for this devastating condition…”
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Influence of variability in the cyclooxygenase pathway on cardiovascular outcomes of nephrosclerosis patients by González, Luz M., Robles, Nicolás R., Mota-Zamorano, Sonia, Valdivielso, José M., González-Rodríguez, Laura, López-Gómez, Juan, Gervasini, Guillermo

“…Nephrosclerosis patients are at an exceptionally high cardiovascular (CV) risk. We aimed to determine whether genetic variability represented by 38 tag-SNPs in…”
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Polymorphisms in glucose homeostasis genes are associated with cardiovascular and renal parameters in patients with diabetic nephropathy by Mota-Zamorano, Sonia, González, Luz M., Robles, Nicolás R., Valdivielso, José M., Arévalo-Lorido, José C., López-Gómez, Juan, Gervasini, Guillermo

“…Diabetic nephropathy (DN) has become the major cause of end-stage kidney disease and is associated to an extremely high cardiovascular (CV) risk. We screened…”
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Vascular Calcification Induced by Chronic Kidney Disease Is Mediated by an Increase of 1α‐Hydroxylase Expression in Vascular Smooth Muscle Cells by Torremadé, Noelia, Bozic, Milica, Panizo, Sara, Barrio‐Vazquez, Sara, Fernandez‐Martín, Jose L, Encinas, Mario, Goltzman, David, Arcidiacono, Maria V, Fernandez, Elvira, Valdivielso, José M

“…ABSTRACT Vascular calcification (VC) is a complication of chronic kidney disease that predicts morbidity and mortality. Uremic serum promotes VC, but the…”
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Predictors of Subclinical Atheromatosis Progression over 2 Years in Patients with Different Stages of CKD by Gracia, Marta, Betriu, Àngels, Martínez-Alonso, Montserrat, Arroyo, David, Abajo, María, Fernández, Elvira, Valdivielso, José M

“…Ultrasonographic detection of subclinical atheromatosis is a noninvasive method predicting cardiovascular events. Risk factors predicting atheromatosis…”
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RANKL Increases Vascular Smooth Muscle Cell Calcification Through a RANK-BMP4–Dependent Pathway by Panizo, Sara, Cardus, Anna, Encinas, Mario, Parisi, Eva, Valcheva, Petya, López-Ongil, Susana, Coll, Blai, Fernandez, Elvira, Valdivielso, Jose M

“…Vascular calcification commonly associated with several pathologies and it has been suggested to be similar to bone mineralization. The axis RANKL-OPG…”
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Association of the rs495392 Klotho polymorphism with atheromatosis progression in patients with chronic kidney disease by Valdivielso, José M, Bozic, Milica, Galimudi, Rajesh Kumar, Bermudez-López, Marcelino, Navarro-González, Juan F, Fernández, Elvira, Betriu, Àngels

“…Prevalence of atherosclerotic cardiovascular disease and its rate of progression are higher in patients with chronic kidney disease (CKD) compared with the…”
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Epigenetic Modification Mechanisms Involved in Inflammation and Fibrosis in Renal Pathology by Rayego-Mateos, Sandra, Ruiz-Ortega, Marta, Kerr, Bredford, Suarez-Alvarez, Beatriz, Dolade, Nuria, Rodrigues-Diez, Raul, Marchant, Vanessa, Morgado-Pascual, Jose Luis, Valdivielso, José Manuel

“…The growing incidence of obesity, hypertension, and diabetes, coupled with the aging of the population, is increasing the prevalence of renal diseases in our…”
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Globotriaosylsphingosine actions on human glomerular podocytes: implications for Fabry nephropathy by SANCHEZ-NINO, Maria D, SANZ, Ana B, CARRASCO, Susana, SALEEM, Moin A, MATHIESON, Peter W, VALDIVIELSO, Jose M, RUIZ-ORTEGA, Marta, EGIDO, Jesus, ORTIZ, Alberto

“…Transforming growth factor-β1 (TGF-β1) and the macrophage inhibitory factor receptor CD74 link the metabolic disorder with tissue injury in diabetic…”
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Magnesium Levels Modify the Effect of Lipid Parameters on Carotid Intima Media Thickness by Cambray, Serafi, Ibarz, Merce, Bermudez-Lopez, Marcelino, Marti-Antonio, Manuel, Bozic, Milica, Fernandez, Elvira, Valdivielso, Jose M

“…Classical risk factors of atherosclerosis in the general population show paradoxical effects in chronic kidney disease (CKD) patients. Thus, low low-density…”
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Differential Effects of Vitamin D Analogs on Vascular Calcification by Cardús, Anna, Panizo, Sara, Parisi, Eva, Fernandez, Elvira, Valdivielso, Jose M

“…We tested the effects of calcitriol and its analog paricalcitol on VSMC calcification in vitro and in vivo. For that reason, cells and animals with five‐sixths…”
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Glutamatergic Signaling Maintains the Epithelial Phenotype of Proximal Tubular Cells by BOZIC, Milica, DE ROOIJ, Johan, PARISI, Eva, RUIZ ORTEGA, Marta, FERNANDEZ, Elvira, VALDIVIELSO, José M

“…Epithelial-mesenchymal transition (EMT) contributes to the progression of renal tubulointerstitial fibrosis. The N-methyl-d-aspartate receptor (NMDAR), which…”
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