Search Results - "Valdés Fernandez, Bianca N."
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Fasciola hepatica GST downregulates NF-κB pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model
Published in Scientific reports (19-02-2019)“…Parasitic helminths and helminth-derived molecules have demonstrated to possess powerful anti-inflammatory properties and confirmed therapeutic effects on…”
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Journal Article -
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Personalized health and the coronavirus vaccines—Do individual genetics matter?
Published in BioEssays (01-09-2021)“…Vaccines represent preventative interventions amenable to immunogenetic prediction of how human variability will influence their safety and efficacy. The…”
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Journal Article -
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Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli -lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages
Published in Microbiology spectrum (11-01-2024)“…Sepsis is the consequence of a systemic bacterial infection that exacerbates the immune cell's activation via bacterial products, resulting in the augmented…”
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Fasciola hepatica fatty acid binding protein (Fh12) induces apoptosis and tolerogenic properties in murine bone marrow derived dendritic cells
Published in Experimental parasitology (01-12-2021)“…In a previous study we demonstrated that Fasciola hepatica fatty acid binding protein (Fh12) significantly suppress macrophage function by inhibiting IL-6,…”
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Assessment of Nicotinic Acetylcholine Receptor Detergent Complexes Purity and Stability for Structural Studies
Published in Biophysical journal (16-02-2016)Get full text
Journal Article -
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Fasciola hepatica Glutathione S‐Transferase (FhGST) conformational studies and its effect on the suppression of toll‐like receptors stimulation
Published in The FASEB journal (01-04-2018)“…Fasciola hepatica is a parasite well known as a master of immunomodulation because of its ability to suppress the Th1 immune responses and elicit a strong…”
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Journal Article -
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Fasciola hepatica Glutathione S-Transferase (nFhGST): Its Role in the Activation of Macrophages and Regulation of Proteins Involved in Inflammatory Pathways
Published 01-01-2021“…Studies have demonstrated that helminth and helminth-derived molecules possess potent anti-inflammatory capacities. The helminth Fasciola hepatica is known as…”
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Dissertation -
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