Search Results - "Valéry, Marine"
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FGFR2 fusion in metastatic pancreatic ductal adenocarcinoma: Is there hope?
Published in European journal of cancer (1990) (01-11-2022)Get full text
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Clinical and molecular features of early onset pancreatic adenocarcinoma
Published in International journal of cancer (01-12-2024)“…Pancreatic adenocarcinoma (PDAC) is a major health burden and may become the second cause of death by cancer in developed countries. The incidence of…”
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KRAS , a New Target for Precision Medicine in Colorectal Cancer?
Published in Cancers (12-10-2024)“…Colorectal cancer (CRC) remains a leading cause of cancer-related mortality globally, with significant public health concerns. This review examines the…”
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Organoids for Functional Precision Medicine in Advanced Pancreatic Cancer
Published in Gastroenterology (New York, N.Y. 1943) (01-10-2024)“…Patient-derived organoids (PDOs) are promising tumor avatars that could enable ex vivo drug tests to personalize patients’ treatments in the frame of…”
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Rechallenge After Oxaliplatin-Induced Hypersensitivity Reactions
Published in JAMA oncology (01-03-2023)Get more information
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Oxaliplatin-induced peripheral neuropathy with hepatic arterial versus intravenous infusion in metastatic colorectal cancer
Published in Supportive care in cancer (01-10-2024)“…Background Oxaliplatin, a major drug in metastatic colorectal cancer (mCRC), is responsible for cumulative, dose-limiting peripheral neuropathy (PN). Whether…”
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Automated Detection of Natural Halogenated Compounds from LC‑MS Profiles–Application to the Isolation of Bioactive Chlorinated Compounds from Marine-Derived Fungi
Published in Analytical chemistry (Washington) (20-09-2016)“…A collection of culture extracts obtained from several marine-derived fungal strains collected on the French Atlantic coast was investigated by high…”
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Targetable Molecular Alterations in the Treatment of Biliary Tract Cancers: An Overview of the Available Treatments
Published in Cancers (06-09-2023)“…Biliary tract cancers (BTCs) are rare tumours, most often diagnosed at an unresectable stage, associated with poor prognosis, with a 5-year survival rate not…”
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Immunotherapy and Hepatocellular Cancer: Where Are We Now?
Published in Cancers (01-09-2022)“…Immunotherapy has demonstrated its effectiveness in many cancers. In hepatocellular carcinoma (HCC), promising results shown in the first phase II studies…”
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Precision Medicine in Pancreatic Ductal Adenocarcinoma: The Impact of Targeted Therapies on Survival of Patients Harboring Actionable Mutations
Published in Biomedicines (01-09-2023)“…Background: Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of death by cancer worldwide. Mostly diagnosed with locally advanced or…”
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Abstract A101: Codon-specific KRAS mutations predict survival in advanced pancreatic cancer
Published in Cancer research (Chicago, Ill.) (16-01-2024)“…Abstract Background: How distinct KRAS alterations in pancreatic adenocarcinoma (PDAC) influence tumor initiation and outcomes remains unclear. Moreover, KRAS…”
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Mutations de l'ADN dans les cholangiocarcinomes : cibler IDH1 et autres mutations
Published in Bulletin du cancer (01-11-2022)“…Les cancers des voies biliaires (CVB) sont des cancers rares et de mauvais pronostic, en particulier au stade métastatique avec moins de 7 % de survie à 5 ans…”
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Cholangiocarcinoma with STRN-ALK translocation treated with ALK inhibitors
Published in Digestive and liver disease (01-12-2021)Get full text
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Precision medicine for KRAS wild-type pancreatic adenocarcinomas
Published in European journal of cancer (1990) (01-01-2024)“…KRAS mutation is the most common molecular alteration in pancreatic adenocarcinoma (PDAC), and around 10% of patients harbor KRAS wild-type tumors (KRAS ). A…”
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Oxaliplatin in metastatic colorectal cancer: Does hepatic arterial infusion reduce sensitive neuropathy compared to the intravenous route?
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 95 Background: Oxaliplatin, a major drug in metastatic colorectal cancer (MCRC), is responsible for a cumulative and limiting peripheral…”
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Is liquid biopsy useful in patients with GI malignancies and exclusive peritoneal disease?
Published in Journal of clinical oncology (01-02-2023)“…809 Background: Peritoneal carcinomatosis (PC) is a common manifestation in gastro-intestinal (GI) cancers.10-20 % of patients (pts) will present isolated,…”
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KRAS WT pancreatic adenocarcinomas: Another disease?
Published in Journal of clinical oncology (01-02-2023)“…750 Background: KRAS mutation is the most common molecular alteration (MA) in pancreatic adenocarcinoma (PDAC), and only 8-10% of patients (pts) harbor KRAS…”
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Immunotherapy: Auto-immune toxicity as a predictive factor of response
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e14086 Background: PD-1 and PD-L1 inhibitors have now demonstrated their efficacy. Finding predictive or pre-emptive response factors is crucial…”
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Role of molecular biology in the management of pancreatic cancer
Published in World journal of gastrointestinal oncology (15-07-2024)“…Pancreatic ductal adenocarcinoma (PDAC) presents significant challenges in patient management due to a dismal prognosis, increasing incidence, and limited…”
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