Search Results - "Vakili, Jalal"

CCR5 binds multiple CC-chemokines : MCP-3 acts as a natural antagonist by BLANPAIN, C, MIGEOTTE, I, LEE, B, VAKILI, J, DORANZ, B. J, GOVAERTS, C, VASSART, G, DOMS, R. W, PARMENTIER, M

“…CCR5 was first characterized as a receptor for MIP-1alpha, MIP-1beta, and RANTES, and was rapidly shown to be the main coreceptor for M-tropic human…”
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Epitope Mapping of CCR5 Reveals Multiple Conformational States and Distinct but Overlapping Structures Involved in Chemokine and Coreceptor Function by Lee, B, Sharron, M, Blanpain, C, Doranz, B J, Vakili, J, Setoh, P, Berg, E, Liu, G, Guy, H R, Durell, S R, Parmentier, M, Chang, C N, Price, K, Tsang, M, Doms, R W

“…The chemokine receptor CCR5 is the major coreceptor for R5 human immunodeficiency virus type-1 strains. We mapped the epitope specificities of 18 CCR5…”
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Functional characterization of a human receptor for neuropeptide FF and related peptides by Kotani, Masato, Mollereau, Catherine, Detheux, Michel, Le Poul, Emmanuel, Brézillon, Stéphane, Vakili, Jalal, Mazarguil, Honoré, Vassart, Gilbert, Zajac, Jean‐Marie, Parmentier, Marc

“…Neuropeptides FF (NPFF) and AF (NPAF) are involved in pain modulation and opioid tolerance. These peptides were known to act through uncharacterized G…”
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Multiple Charged and Aromatic Residues in CCR5 Amino-terminal Domain Are Involved in High Affinity Binding of Both Chemokines and HIV-1 Env Protein by Blanpain, C, Doranz, B J, Vakili, J, Rucker, J, Govaerts, C, Baik, S S, Lorthioir, O, Migeotte, I, Libert, F, Baleux, F, Vassart, G, Doms, R W, Parmentier, M

“…CCR5 is a functional receptor for MIP-1α, MIP-1β, RANTES (regulated on activation normal T cell expressed), MCP-2, and MCP-4 and constitutes the main…”
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Quantum Proteolytic Activation of Chemokine CCL15 by Neutrophil Granulocytes Modulates Mononuclear Cell Adhesiveness by Richter, Rudolf, Bistrian, Roxana, Escher, Sylvia, Forssmann, Wolf-Georg, Vakili, Jalal, Henschler, Reinhard, Spodsberg, Nikolaj, Frimpong-Boateng, Adjoa, Forssmann, Ulf

“…Monocyte infiltration into inflammatory sites is generally preceded by neutrophils. We show here that neutrophils may support this process by activation of…”
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Extracellular Cysteines of CCR5 Are Required for Chemokine Binding, but Dispensable for HIV-1 Coreceptor Activity by Blanpain, C, Lee, B, Vakili, J, Doranz, B J, Govaerts, C, Migeotte, I, Sharron, M, Dupriez, V, Vassart, G, Doms, R W, Parmentier, M

“…CCR5 is the major coreceptor for macrophage-tropic human immunodeficiency virus type I (HIV-1). For most G-protein-coupled receptors that have been tested so…”
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Results of the Belgian expanded access program of eribulin in the treatment of metastatic breast cancer closely mirror those of the pivotal phase III trial by Aftimos, Philippe, Polastro, Laura, Ameye, Lieveke, Jungels, Christiane, Vakili, Jalal, Paesmans, Marianne, van den Eerenbeemt, Joanne, Buttice, Alfino, Gombos, Andrea, de Valeriola, Dominique, Gil, Thierry, Piccart-Gebhart, Martine, Awada, Ahmad

“…Abstract Background Eribulin is a non-taxane microtubule dynamics inhibitor that showed a survival benefit versus treatment of physician's choice in a phase…”
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NR2F2 controls malignant squamous cell carcinoma state by promoting stemness and invasion and repressing differentiation by Mauri, Federico, Schepkens, Corentin, Lapouge, Gaëlle, Drogat, Benjamin, Song, Yura, Pastushenko, Ievgenia, Rorive, Sandrine, Blondeau, Jeremy, Golstein, Sophie, Bareche, Yacine, Miglianico, Marie, Nkusi, Erwin, Rozzi, Milena, Moers, Virginie, Brisebarre, Audrey, Raphaël, Maylis, Dubois, Christine, Allard, Justine, Durdu, Benoit, Ribeiro, Floriane, Sotiriou, Christos, Salmon, Isabelle, Vakili, Jalal, Blanpain, Cédric

“…The nongenetic mechanisms required to sustain malignant tumor state are poorly understood. During the transition from benign tumors to malignant carcinoma,…”
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Abstract 3891: Tackling the obstacles facing the implementation of a molecular screening program in an early drug development unit: The Jules Bordet Institute Program for Molecular Profiling of Metastatic Lesions - feasibility (Precision-f) by Aftimos, Philippe G., Maetens, Marion, Sibille, Catherine, Laes, Jean-François, Brohée, Sylvain, Berghmans, Thierry, Kerger, Joseph, Hendlisz, Alain, Irrthum, Alexandre, De Henau, Olivier, Deleporte, Amélie, Drisis, Stylianos, Larsimont, Denis, Vakili, Jalal, Sotiriou, Christos, Piccart, Martine, Awada, Ahmad

“…Abstract Introduction The identification of pathways involved in carcinogenesis, the emergence of high-throughput technologies enabling tumor molecular…”
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CCR5 Binds Multiple CC-Chemokines: MCP-3 Acts as a Natural Antagonist by Blanpain, Cédric, Migeotte, Isabelle, Lee, Benhur, Vakili, Jalal, Doranz, Benjamin J., Govaerts, Cédric, Vassart, Gilbert, Doms, Robert W., Parmentier, Marc

“…CCR5 was first characterized as a receptor for MIP-1, MIP-1β, and RANTES, and was rapidly shown to be the main coreceptor for M-tropic human immunodeficiency…”
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Significance of N-Terminal Proteolysis of CCL14a to Activity on the Chemokine Receptors CCR1 and CCR5 and the Human Cytomegalovirus-Encoded Chemokine Receptor US28 by Richter, Rudolf, Casarosa, Paola, Standker, Ludger, Munch, Jan, Springael, Jean-Yves, Nijmeijer, Saskia, Forssmann, Wolf-Georg, Vischer, Henry F, Vakili, Jalal, Detheux, Michel, Parmentier, Marc, Leurs, Rob, Smit, Martine J

“…The CC chemokine CCL14a is constitutively expressed in a large variety of tissues and its inactive proform CCL14a(1-74) circulates in high concentrations in…”
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Natural proteolytic processing of hemofiltrate CC chemokine 1 generates a potent CC chemokine receptor (CCR)1 and CCR5 agonist with anti-HIV properties by Detheux, M, Ständker, L, Vakili, J, Münch, J, Forssmann, U, Adermann, K, Pöhlmann, S, Vassart, G, Kirchhoff, F, Parmentier, M, Forssmann, W G

“…Hemofiltrate CC chemokine (HCC)-1 is a recently described human chemokine that is constitutively expressed in numerous tissues and is present at high…”
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Urokinase Plasminogen Activator and Plasmin Efficiently Convert Hemofiltrate CC Chemokine 1 into Its Active [9-74] Processed Variant by Vakili, Jalal, Standker, Ludger, Detheux, Michel, Vassart, Gilbert, Forssmann, Wolf-Georg, Parmentier, Marc

“…Abstract We have previously isolated from human hemofiltrate an N-terminally truncated form of the hemofiltrate CC chemokine 1 (HCC-1), and characterized…”
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