Factors influencing choice of chemotherapy in metastatic colorectal cancer (mCRC)

Management of metastatic colorectal cancer requires a multimodal approach and must be performed by an experienced, multidisciplinary expert team. The optimal choice of the individual treatment modality, according to disease localization and extent, tumor biology, and patient clinical characteristics...

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Bibliographic Details
Published in:	Cancer management and research Vol. 5; no. default; pp. 377 - 385
Main Authors:	Rossi, Luigi, Vakiarou, Foteini, Zoratto, Federica, Bianchi, Loredana, Papa, Anselmo, Basso, Enrico, Verrico, Monica, Lo Russo, Giuseppe, Evangelista, Salvatore, Rinaldi, Guilia, Perrone-Congedi, Francesca, Spinelli, Gian Paolo, Stati, Valeria, Caruso, Davide, Prete, Alessandra, Tomao, Silverio
Format:	Journal Article
Language:	English
Published:	New Zealand Dove Medical Press Limited 19-11-2013 Taylor & Francis Ltd Dove Press Dove Medical Press
Subjects:	Cancer Care and treatment Colorectal cancer Metastasis metastatic colorectal cancer multidisciplinary approach Oncology, Experimental patient clinical features Patients Review tumor biology metastatic colorectal cancer tumor biology multidisciplinary approach patient clinical features
Online Access:	Get full text
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Summary:	Management of metastatic colorectal cancer requires a multimodal approach and must be performed by an experienced, multidisciplinary expert team. The optimal choice of the individual treatment modality, according to disease localization and extent, tumor biology, and patient clinical characteristics, will be one that can maintain quality of life and long-term survival, and even cure selected patients. This review is an overview of the different therapeutic approaches available in metastatic colorectal cancer, for the purpose of defining personalized therapeutic algorithms according to tumor biology and patient clinical features.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1
ISSN:	1179-1322 1179-1322
DOI:	10.2147/CMAR.S47986