Search Results - "Vaishali, M"
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A systematic review on use of aminoquinolines for the therapeutic management of COVID-19: Efficacy, safety and clinical trials
Published in Life sciences (1973) (01-08-2020)“…Recent global outbreak of the pandemic caused by coronavirus (COVID-19) emphasizes the urgent need for novel antiviral therapeutics. It can be supplemented by…”
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Chromones: Privileged scaffold in anticancer drug discovery
Published in Chemical biology & drug design (01-11-2021)“…In the design and discovery of anticancer drugs, various natural heterocyclic scaffolds have attracted considerable interest as privileged structures. For…”
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Quantum Chemical and Docking Insights into Bioavailability Enhancement of Curcumin by Piperine in Pepper
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (26-05-2016)“…We combine quantum chemical and molecular docking techniques to provide new insights into how piperine molecule in various forms of pepper enhances…”
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Mutation informatics: SARS-CoV-2 receptor-binding domain of the spike protein
Published in Drug discovery today (01-10-2022)“…•Mutation informatics study on RBD of SARS-CoV-2 variants.•Discussion of small molecules targeting the RBD/ACE2 interface.•Ideation to design novel inhibitors…”
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Role of CSF1R Inhibitor Pexidartinib for the Treatment of Cancer
Published in Russian journal of bioorganic chemistry (01-12-2022)“…Pexidartinib is an orally active small molecule inhibitor of tyrosine kinase. It is selective towards the colony-stimulating factor 1 receptor (CSF1R) and has…”
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Cobalt molybdate nanoflowers decorated bio-waste derived porous activated carbon nanocomposite: A high performance electrode material for supercapacitors
Published in Chemosphere (Oxford) (01-06-2024)“…In this work, we report a supercapacitor electrode material based on nano-flower like cobalt molybdate decorated on porous activated carbon derived from waste…”
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Artificial intelligence and machine-learning approaches in structure and ligand-based discovery of drugs affecting central nervous system
Published in Molecular diversity (01-04-2023)“…CNS disorders are indications with a very high unmet medical needs, relatively smaller number of available drugs, and a subpar satisfaction level among…”
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Natural Product Databases and Tools for Anti-cancer Drug Discovery
Published in Mini reviews in medicinal chemistry (01-01-2021)“…Throughout the ages, compounds collected and/or isolated from natural sources have been the basic source of medicinal agents against a variety of diseases. The…”
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Promising Schiff bases in antiviral drug design and discovery
Published in Medicinal chemistry research (2023)“…Emerging and re-emerging illnesses will probably present a new hazard of infectious diseases and have fostered the urge to research new antiviral agents. Most…”
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Recent Studies on Design and Development of Drugs Against Alzheimer's Disease (AD) Based on Inhibition of BACE-1 and Other AD-causative Agents
Published in Current topics in medicinal chemistry (01-01-2020)“…Alzheimer's disease (AD) is one of the neurodegenerative diseases and has been hypothesized to be a protein misfolding disease. In the generation of AD,…”
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Selective inhibition of T-type calcium channel preserves ischemic pre-conditioning mediated neuroprotection during cerebral ischemia reperfusion injury in diabetic mice
Published in Metabolic brain disease (21-11-2024)“…Ischemic preconditioning (IPC) provides ischemic tolerance and neuroprotection during cerebral ischemia reperfusion (CI/R) injury. Diabetes abolishes the…”
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Synthesis and supercapacitor performance of Sm3RuO7 nanorods and Sm3RuO7/MnO2 nanocomposite
Published in Journal of materials science. Materials in electronics (01-03-2024)“…In this work, we report the synthesis of Samarium ruthenate (Sm 3 RuO 7 ) in the form of nanorods for the first time using the hydrothermal method, and Sm 3…”
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Ultrasound-assisted chemoenzymatic epoxidation of soybean oil by using lipase as biocatalyst
Published in Ultrasonics sonochemistry (01-01-2018)“…[Display omitted] •Ultrasound assisted lipase catalyzed synthesis of epoxidized soybean oil was performed.•Process parameters for synthesis of epoxidized…”
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Molecular Processes Exploited as Drug Targets for Cancer Chemotherapy
Published in Anti-cancer agents in medicinal chemistry (01-01-2021)“…Cancer is an uncontrolled malignant tumor growth taking place in any tissue of the body and attains complex diversity which makes it difficult for oncologists…”
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Therapeutic Outcomes of Isatin and Its Derivatives against Multiple Diseases: Recent Developments in Drug Discovery
Published in Pharmaceuticals (Basel, Switzerland) (22-02-2022)“…Isatin (1 indole 2, 3-dione) is a heterocyclic, endogenous lead molecule recognized in humans and different plants. The isatin nucleus and its derivatives are…”
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Healthy Drinking Water as a Necessity in Developing Countries Like India: A Narrative review
Published in Curēus (Palo Alto, CA) (18-10-2023)“…Water is an indispensable part of human life. This article is an extensive review that focuses on the importance of water to sustain human life, the necessity…”
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Prospective mode of action of Ivermectin: SARS-CoV-2
Published in European journal of medicinal chemistry reports (01-04-2022)“…The well-known anti-helminthic drug ivermectin (IVM) has been established as an example of drug repurposing for the management of SARS-CoV-2 infection. Various…”
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Safe and Effective Kinase Inhibitors for the Treatment of Gynecological Cancers: In Silico Approach
Published in Current drug metabolism (01-01-2021)“…This study aimed at studying various types of gynecological cancers and the available therapeutics to investigate safe and effective drugs. Cancer is the most…”
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Rapid ‘one-pot’ synthesis of a novel benzimidazole-5-carboxylate and its hydrazone derivatives as potential anti-inflammatory and antimicrobial agents
Published in Bioorganic & medicinal chemistry letters (01-04-2015)“…[Display omitted] A novel series of N-arylidene-2-(2,4-dichloro phenyl)-1-propyl-1H-benzo[d] imidazole-5-carbohydrazides having different substitution on the…”
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