Search Results - "Vaisberg, Abraham J."

Synthesis, antileishmanial activity and cytotoxicity of 2,3-diaryl- and 2,3,8-trisubstituted imidazo[1,2-a]pyrazines by Marchand, Pascal, Bazin, Marc-Antoine, Pagniez, Fabrice, Rivière, Guillaume, Bodero, Lizeth, Marhadour, Sophie, Nourrisson, Marie-Renée, Picot, Carine, Ruchaud, Sandrine, Bach, Stéphane, Baratte, Blandine, Sauvain, Michel, Pareja, Denis Castillo, Vaisberg, Abraham J., Le Pape, Patrice

“…A series of original 2-phenyl-3-(pyridin-4-yl)imidazo[1,2-a]pyrazines and the 3-iodo precursors, bearing a polar moiety at the C-8 position, was synthesized…”
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Plagiochiline A Inhibits Cytokinetic Abscission and Induces Cell Death by Stivers, Nicole S, Islam, Ashraful, Reyes-Reyes, Elsa M, Casson, Lavona K, Aponte, José C, Vaisberg, Abraham J, Hammond, Gerald B, Bates, Paula J

“…We previously reported on the isolation and biological activities of plagiochiline A ( ), a 2,3-secoaromadendrane-type sesquiterpenoid from the Peruvian…”
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Antimycobacterial Metabolites from Plectranthus: Royleanone Derivatives against Mycobacterium tuberculosis Strains by Rijo, Patrícia, Simões, M. Fátima, Francisco, A. Paula, Rojas, Rosario, Gilman, Robert H., Vaisberg, Abraham J., Rodríguez, Benjamín, Moiteiro, Cristina

“…The antimycobacterial activities of eight diterpenes, 1–8, isolated previously from Plectranthus and eleven esters, 9–19, of…”
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A Multipronged Approach to the Study of Peruvian Ethnomedicinal Plants: A Legacy of the ICBG-Peru Project by Aponte, José C, Vaisberg, Abraham J, Rojas, Rosario, Sauvain, Michel, Lewis, Walter H, Lamas, Gerardo, Sarasara, César, Gilman, Robert H, Hammond, Gerald B

“…A multidisciplinary and international team of scientists was assembled in the early 1990s to conduct an ethnobotanical study of plants used by the Aguaruna…”
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Physangulidine A, a Withanolide from Physalis angulata, Perturbs the Cell Cycle and Induces Cell Death by Apoptosis in Prostate Cancer Cells by Reyes-Reyes, E. Merit, Jin, Zhuang, Vaisberg, Abraham J, Hammond, Gerald B, Bates, Paula J

“…Recently, our group reported the discovery of three new withanolides, physangulidines A–C, from Physalis angulata. In this study, the biological effects of…”
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Synthesis, Cytotoxicity, and Anti-Trypanosoma cruzi Activity of New Chalcones by Aponte, José C, Verástegui, Manuela, Málaga, Edith, Zimic, Mirko, Quiliano, Miguel, Vaisberg, Abraham J, Gilman, Robert H, Hammond, Gerald B

“…Synthesis of a cytotoxic dihydrochalcone, first isolated from a traditional Amazonian medicinal plant Iryanthera juruensis Warb (Myristicaceae), followed by a…”
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Ethnobotany, phytochemistry and pharmacology of Uncaria (Rubiaceae) by Heitzman, Mary E., Neto, Catherine C., Winiarz, Elizabeth, Vaisberg, Abraham J., Hammond, Gerald B.

“…A review of the pharmacology and phytochemistry of Uncaria. Emphasis is placed on new compounds and recent pharmacological studies, which are reported…”
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A survey of traditional medicinal plants from the Callejón de Huaylas, Department of Ancash, Perú by Hammond, Gerald B, Fernández, Irma D, Villegas, León F, Vaisberg, Abraham J

“…The medicinal uses of local flora from the Callejón de Huaylas, Department of Ancash, northeastern Perú, are reported. This geographical area has an old…”
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Antibacterial activity of some Peruvian medicinal plants from the Callejon de Huaylas by Neto, Catherine C., Owens, Charles W., Langfield, Richard D., Comeau, Anthony B., Onge, Julie St, Vaisberg, Abraham J., Hammond, Gerald B.

“…Extracts of eight medicinal plants from the Callejon de Huaylas in Peru were screened for antibacterial activity in eighteen bacterial strains by the…”
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Physangulidines A, B, and C: Three New Antiproliferative Withanolides from Physalis angulata L by Jin, Zhuang, Mashuta, Mark S, Stolowich, Neal J, Vaisberg, Abraham J, Stivers, Nicole S, Bates, Paula J, Lewis, Walter H, Hammond, Gerald B

“…Bioassay-directed fractionation of the whole plant of Physalis angulata L. afforded three new antiproliferative withanolides with an unusual carbon framework:…”
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A Bioactive Spirolactone Iridoid and Triterpenoids from Himatanthus sucuuba by WOOD, Christina A., LEE, Kit, VAISBERG, Abraham J., KINGSTON, David G.I., NETO, Catherine C., HAMMOND, Gerald B.

“…Himatanthus sucuuba is an Amazonian tree with abundant, yet conflicting ethnobotanical information. Investigation of the polar and non-polar constituents led…”
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Discovery of Novel (Imidazo[1,2-a]pyrazin-6-yl)ureas as Antiproliferative Agents Targeting P53 in Non-small Cell Lung Cancer Cell Lines by Bazin, Marc-Antoine, Rousseau, Bénédicte, Marhadour, Sophie, Tomasoni, Christophe, Evenou, Pierre, Piessard, Sylvie, Vaisberg, Abraham J, Ruchaud, Sandrine, Bach, Stéphane, Roussakis, Christos, Marchand, Pascal

“…A series of (imidazo[1,2-a]pyrazin-6-yl)ureas were synthesized through 6-aminoimidazo[1,2-a]pyrazine as a key intermediate…”
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Trypanoside, anti-tuberculosis, leishmanicidal, and cytotoxic activities of tetrahydrobenzothienopyrimidines by Aponte, José C., Vaisberg, Abraham J., Castillo, Denis, Gonzalez, German, Estevez, Yannick, Arevalo, Jorge, Quiliano, Miguel, Zimic, Mirko, Verástegui, Manuela, Málaga, Edith, Gilman, Robert H., Bustamante, Juan M., Tarleton, Rick L., Wang, Yuehong, Franzblau, Scott G., Pauli, Guido F., Sauvain, Michel, Hammond, Gerald B.

“…The synthesis of 2-(5,6,7,8-tetrahydro[1]benzothieno[2,3- d]pyrimidin-4-yl)hydrazone-derivatives (BTPs) and their in vitro evaluation against Trypanosoma cruzi…”
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MALDI-TOF MS characterization of proanthocyanidins from cranberry fruit (Vaccinium macrocarpon) that inhibit tumor cell growth and matrix metalloproteinase expression in vitro by Neto, C.C, Krueger, C.G, Lamoureaux, T.L, Kondo, M, Vaisberg, A.J, Hurta, R.A.R, Curtis, S, Matchett, M.D, Yeung, H, Sweeney, M.I

“…Proanthocyanidin-rich extracts were prepared by fractionation of the fruit of the North American cranberry (Vaccinium macrocarpon). In vitro growth inhibition…”
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Cytotoxic and anti-infective phenolic compounds isolated from Mikania decora and Cremastosperma microcarpum by Aponte, José C, Jin, Zhuang, Vaisberg, Abraham J, Castillo, Denis, Málaga, Edith, Lewis, Walter H, Sauvain, Michel, Gilman, Robert H, Hammond, Gerald B

“…An anticancer-bioassay guided isolation of the ethanol extract and fractions of two plants from the Peruvian rainforest, Mikania decora and Cremastosperma…”
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In Vivo Wound-Healing Activity of Oleanolic Acid Derived from the Acid Hydrolysis of Anredera diffusa by Moura-Letts, G, Villegas, L.F, Marçalo, A, Vaisberg, A.J, Hammond, G.B

“…Anredera diffusa is used as a wound-healing agent in traditional Peruvian medicine. Acid hydrolysis of the bioactive ethanolic extract, followed by in vivo…”
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Identification of Triterpene Hydroxycinnamates with in Vitro Antitumor Activity from Whole Cranberry Fruit (Vaccinium macrocarpon) by Murphy, Brian T, MacKinnon, Shawna L, Yan, Xiaojun, Hammond, Gerald B, Vaisberg, Abraham J, Neto, Catherine C

“…Bioactivity-guided fractionation of cranberry fruit was used to determine the identity of triterpenoid esters from Vaccinium macrocarpon, which inhibit tumor…”
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Cytotoxic and anti-infective sesquiterpenes present in Plagiochila disticha (Plagiochilaceae) and Ambrosia peruviana (Asteraceae) by Aponte, José C, Yang, Han, Vaisberg, Abraham J, Castillo, Denis, Málaga, Edith, Verástegui, Manuela, Casson, Lavona K, Stivers, Nicole, Bates, Paula J, Rojas, Rosario, Fernandez, Irma, Lewis, Walter H, Sarasara, César, Sauvain, Michel, Gilman, Robert H, Hammond, Gerald B

“…A pharmacological screening of the ethanol extract and fractions of two Peruvian medicinal plants, Plagiochila disticha and Ambrosia peruviana, led to the…”
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Aegicerin, the First Oleanane Triterpene with Wide-Ranging Antimycobacterial Activity, Isolated from Clavija procera by Rojas, R, Caviedes, L, Aponte, J.C, Vaisberg, A.J, Lewis, W.H, Lamas, G, Sarasara, C, Gilman, R.H, Hammond, G.B

“…An ethanol extract of the Peruvian plant Clavija procera, a member of the rare Theophrastaceae family, was fractionated using a colorimetric bioassay-guided…”
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Isolation of Cytotoxic Metabolites from Targeted Peruvian Amazonian Medicinal Plants by Aponte, José C, Vaisberg, Abraham J, Rojas, Rosario, Caviedes, Luz, Lewis, Walter H, Lamas, Gerardo, Sarasara, César, Gilman, Robert H, Hammond, Gerald B

“…The antiproliferative bioassay-guided fractionation of five Peruvian plants, Doliocarpus dentatus, Picramnia sellowii, Strychnos mitscherlichii, Iryanthera…”
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