Search Results - "Vaira, V"
-
1
MicroRNAs in parathyroid physiopathology
Published in Molecular and cellular endocrinology (15-11-2017)“…Parathyroid glands regulate calcium homeostasis through synthesis and secretion of parathormone (PTH). They sense the extracellular calcium concentration…”
Get full text
Journal Article -
2
Dopamine receptor type 2 (DRD2) inhibits migration and invasion of human tumorous pituitary cells through ROCK-mediated cofilin inactivation
Published in Cancer letters (28-10-2016)“…Highlights • DRD2 agonist inhibits NFPT cell migration and invasion. • DRD2 agonist increases cofilin phosphorylation (inactivation) in NFPT cells. • The…”
Get full text
Journal Article -
3
Regulation of survivin expression by IGF-1 mTOR signaling
Published in Oncogene (26-04-2007)“…Survivin is a dual regulator of cell proliferation and cell viability overexpressed in most human tumors. Although strategies to lower survivin levels have…”
Get full text
Journal Article -
4
Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue
Published in Endocrine-related cancer (01-03-2010)“…Parathyroid carcinoma (PaC) is a rare cause of primary hyperparathyroidism. Though the loss of the oncosuppressor CDC73/HRPT2 gene product, parafibromin, has…”
Get full text
Journal Article -
5
Dopamine receptor type 2 (DRD2) and somatostatin receptor type 2 (SSTR2) agonists are effective in inhibiting proliferation of progenitor/stem‐like cells isolated from nonfunctioning pituitary tumors
Published in International journal of cancer (15-04-2017)“…The role of progenitor/stem cells in pituitary tumorigenesis, resistance to pharmacological treatments and tumor recurrence is still unclear. This study…”
Get full text
Journal Article -
6
MicroRNA deregulation in parathyroid tumours suggests an embryonic signature
Published in Journal of endocrinological investigation (01-04-2015)“…Primary hyperparathyroidism is a common endocrine disorder caused by abnormal tumour parathyroid cell proliferation. Parathyroid tumours show a great…”
Get full text
Journal Article -
7
miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression
Published in Oncogene (05-01-2012)“…The expression of small, non-coding RNA or microRNAs (miR), is frequently deregulated in human cancer, but how these pathways affect disease progression is…”
Get full text
Journal Article -
8
Diagnostic Yield of Transbronchial Cryobiopsies for the Diagnosis of Rejection in Lung Transplant Patients
Published in The Journal of heart and lung transplantation (01-04-2020)“…Transbronchial biopsy (TBB) using forceps is the standard procedure to establish the presence of allograft rejection after lung transplantation. However,…”
Get full text
Journal Article -
9
miRNAs-Directed Signaling in Lung Transplantation Reveals Differential Transcription Factors Expression in Acute or Chronic Lung Dysfunction
Published in The Journal of heart and lung transplantation (01-04-2020)“…In a previous study on miRNA profiling in bronchoalveolar lavage (BAL) fluid of lung transplanted (LTx) patients we obtained signatures of deregulated miRNAs…”
Get full text
Journal Article -
10
The expression of Axl receptor tyrosine kinase influences the tumour phenotype and clinical outcome of patients with malignant pleural mesothelioma
Published in British journal of cancer (19-02-2013)“…Background: Recent preclinical studies identified Axl, a tyrosine kinase receptor implicated in tumour progression and epithelial-to-mesenchymal transition, as…”
Get full text
Journal Article -
11
Identification of imaging biomarkers for the assessment of tumour response to different treatments in a preclinical glioma model
Published in European journal of nuclear medicine and molecular imaging (01-06-2015)“…Purpose Hypoxia-inducible factor 1α (HIF-1α) activity is one of the major players in hypoxia-mediated glioma progression and resistance to therapies, and…”
Get full text
Journal Article -
12
-
13
EGFR overexpression in malignant pleural mesothelioma an immunohistochemical and molecular study with clinico-pathological correlations
Published in Lung cancer (Amsterdam, Netherlands) (01-02-2006)“…The epidermal growth factor receptor (EGFR) is overexpressed in many epithelial malignancies, against which some antitumoral drugs have been developed. There…”
Get full text
Journal Article -
14
PO-080 V-ATPase G1 expression in human glioma stem cells correlates with ERK activation
Published in ESMO open (01-07-2018)“…IntroductionThe vacuolar ATPase (V-ATPase) is a multisubunit proton pump acting in multiple processes in eukaryotic cells. Alteration of V-ATPase activity is…”
Get full text
Journal Article -
15
The intra-tumor heterogeneity of C19MC miRNA cluster expression mirrors the presence of the side population in HCC
Published in Digestive and liver disease (10-02-2016)Get full text
Journal Article -
16
A distinct miRNA expression profile in hepatocellular carcinoma arising in carriers of the I148M PNPLA3 gene variant
Published in Digestive and liver disease (07-10-2015)Get full text
Journal Article -
17
PO-450 Interplay between coding and non-coding genome in human parathyroid tumours
Published in ESMO open (01-07-2018)“…IntroductionParathyroid tumours are the second most common endocrine neoplasia in women, after thyroid cancer. Mutations in the oncosuppressor CDC73 are the…”
Get full text
Journal Article -
18
PO-298 MYC favours the onset of tumour initiating cells by inducing epigenetic reprogramming of mammary epithelial cells towards a stem cell-like state
Published in ESMO open (01-07-2018)“…IntroductionBreast cancer consists of highly heterogenous tumours whose cell of origin resulted difficult to be defined. Recent findings highlighted the…”
Get full text
Journal Article -
19
EGFR overexpression in malignant pleural mesothelioma
Published in Lung cancer (Amsterdam, Netherlands) (01-02-2006)“…The epidermal growth factor receptor (EGFR) is overexpressed in many epithelial malignancies, against which some antitumoral drugs have been developed. There…”
Get full text
Journal Article -
20
(109) Insights Into the Lung Microenvironment During Chronic Allograft Rejection: The Role of Bal-Evs in Rewiring Respiratory Cells Inflammatory Response
Published in The Journal of heart and lung transplantation (01-04-2023)“…Little is known about the pathomolecular signaling in the lung microenvironment that precedes and drives graft rejection, the major cause of graft failure and…”
Get full text
Journal Article