Search Results - "Vainionpää, Vilho"
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Persistent default-mode network connectivity during light sedation
Published in Human brain mapping (01-07-2008)“…The default‐mode network (DMN) is a set of specific brain regions whose activity, predominant in the resting‐state, is attenuated during cognitively demanding,…”
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Midazolam sedation increases fluctuation and synchrony of the resting brain BOLD signal
Published in Magnetic resonance imaging (01-05-2005)“…The blood oxygen level-dependent (BOLD) magnetic resonance signal of functional brain cortices is dominated by very low frequency (VLF) fluctuations in…”
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Ph-stat versus alpha-stat perfusion strategy during experimental hypothermic circulatory arrest: a microdialysis study
Published in The Annals of thoracic surgery (01-10-2003)“…The superiority of the pH-stat to the α-stat acid-base strategy during cardiopulmonary bypass as a neuroprotective method during hypothermic circulatory arrest…”
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Fructose-1,6-bisphosphate for improved outcome after hypothermic circulatory arrest in pigs
Published in The Journal of thoracic and cardiovascular surgery (01-03-2003)“…Objective: Fructose-1,6-bisphosphate is a high-energy intermediate in the anaerobic metabolism. It enhances glycolysis, preserves cellular adenosine…”
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Leukocyte filtration improves brain protection after a prolonged period of hypothermic circulatory arrest: A study in a chronic porcine model
Published in The Journal of thoracic and cardiovascular surgery (01-12-2000)“…Background: Ischemic cerebral injury follows a well-attested sequence of events, including 3 phases: depolarization, biochemical cascade, and reperfusion…”
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Potential neuroprotective benefits of erythropoietin during experimental hypothermic circulatory arrest
Published in The Journal of thoracic and cardiovascular surgery (01-10-2002)“…Objective: Recent studies have shown that erythropoietin protects neurons from glutamate toxicity and ischemia. This study was performed to evaluate the…”
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Prolonged mild hypothermia after experimental hypothermic circulatory arrest in a chronic porcine model
Published in The Journal of thoracic and cardiovascular surgery (01-04-2002)“…Objectives: We sought to evaluate the potential efficacy of prolonged mild hypothermia after hypothermic circulatory arrest. Methods: Twenty pigs, after a…”
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Topical head cooling during rewarming after experimental hypothermic circulatory arrest
Published in The Annals of thoracic surgery (01-06-2003)“…The aim of this study was to evaluate the potential neuroprotective effect of topical head cooling during the first 2 postoperative hours after experimental…”
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Lamotrigine plus leukocyte filtration as a neuroprotective strategy in experimental hypothermic circulatory arrest
Published in The Annals of thoracic surgery (2002)“…Background. Lamotrigine and leukocyte filtration seem to improve cerebral protection during experimental hypothermic circulatory arrest (HCA). This study was…”
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The N-methyl-D -aspartate antagonist memantine has no neuroprotective effect during hypothermic circulatory arrest: A study in the chronic porcine model
Published in The Journal of thoracic and cardiovascular surgery (01-05-2001)“…Background: Glutamate excitotoxicity has an important role in the development of brain injury after prolonged hypothermic circulatory arrest. The goal of the…”
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Lamotrigine improves cerebral outcome after hypothermic circulatory arrest: A study in a chronic porcine model
Published in The Journal of thoracic and cardiovascular surgery (01-08-2000)“…Background: Glutamate excitotoxicity has an important role in the development of brain injury after prolonged hypothermic circulatory arrest. The goal of the…”
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Determinants of mortality after hypothermic circulatory arrest in a chronic porcine model
Published in European journal of cardio-thoracic surgery (01-10-2001)“…Objective: Beside neurological morbidity, mortality is a relevant end-point of experimental porcine model of hypothermic circulatory arrest (HCA) and this…”
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Slow vasomotor fluctuation in fMRI of anesthetized child brain
Published in Magnetic resonance in medicine (01-09-2000)“…Signal intensity changes in fMRI during rest caused by vasomotor fluctuations were investigated in this work. Resting‐state baseline fluctuations were…”
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pH-Stat Versus α-Stat Acid–Base Management Strategy During Hypothermic Circulatory Arrest Combined With Embolic Brain Injury
Published in The Annals of thoracic surgery (01-04-2005)“…There is some evidence of beneficial metabolic effects associated with the pH-stat than with α-stat perfusion strategy, but this is tempered by a likely…”
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Leukocyte filter enhances neutrophil activation during combined aortic valve and coronary artery bypass surgery
Published in The Heart surgery forum (2006)“…Cardiopulmonary bypass-induced systemic inflammatory reaction involving the expression of neutrophil surface adhesion molecules is the main mechanism leading…”
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Topical head cooling during rewarming after experimental hypothermic circulatory arrest. Commentary
Published in The Annals of thoracic surgery (2003)Get full text
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The role of cerebral microdialysis in predicting the outcome after experimental hypothermic circulatory arrest
Published in Scandinavian cardiovascular journal : SCJ (01-12-2001)“…To evaluate whether and which of the cerebral microdialysis parameters are predictive of postoperative outcome after an experimental 75-min period of…”
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