Search Results - "Vaiman, Daniel"
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Oxidative Stress in Preeclampsia and Placental Diseases
Published in International journal of molecular sciences (17-05-2018)“…Preeclampsia is a persistent hypertensive gestational disease characterized by high blood pressure and proteinuria, which presents from the second trimester of…”
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2
Genetic regulation of recurrent spontaneous abortion in humans
Published in Biomedical journal (01-01-2015)“…Recurrent pregnancy loss, defined as a pregnancy failure occurring before 24 weeks of gestation more than two or three times according to most definitions, is…”
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3
Exploring the Molecular Aetiology of Preeclampsia by Massive Parallel Sequencing of DNA
Published in Current hypertension reports (01-04-2020)“…Purpose of Review This manuscript aims to review (for the first time) studies describing NGS sequencing of preeclampsia (PE) women’s DNA. Recent Findings…”
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The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia
Published in International journal of molecular sciences (11-06-2019)“…In this review, we comprehensively present the function of epigenetic regulations in normal placental development as well as in a prominent disease of…”
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Landscape of transcriptional deregulations in the preeclamptic placenta
Published in PloS one (13-06-2013)“…Preeclampsia is a pregnancy disease affecting 5 to 8% of pregnant women and a leading cause of both maternal and fetal mortality and morbidity. Because of a…”
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Genomics of Endometriosis: From Genome Wide Association Studies to Exome Sequencing
Published in International journal of molecular sciences (07-07-2021)“…This review aims at better understanding the genetics of endometriosis. Endometriosis is a frequent feminine disease, affecting up to 10% of women, and…”
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An Integrative Analysis of Preeclampsia Based on the Construction of an Extended Composite Network Featuring Protein-Protein Physical Interactions and Transcriptional Relationships
Published in PloS one (01-11-2016)“…Preeclampsia (PE) is a pregnancy disorder defined by hypertension and proteinuria. This disease remains a major cause of maternal and fetal morbidity and…”
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Modeling Preeclampsia In Vitro: Polymorphic Variants of STOX1-A/B Genes Can Downregulate CD24 in Trophoblast Cell Lines
Published in International journal of molecular sciences (14-12-2022)“…CD24 is a mucin-like immunosuppressing glycoprotein whose levels increase during pregnancy and decrease in the syncytio- and cytotrophoblasts in early and…”
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Prevention of gravidic endothelial hypertension by aspirin treatment administered from the 8th week of gestation
Published in Hypertension research (01-10-2011)“…The aim of this study was to evaluate whether low doses of aspirin (100 mg per day) administered to a homogeneous population of women early (8-10 weeks) during…”
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Mutant Cohesin in Premature Ovarian Failure
Published in The New England journal of medicine (06-03-2014)“…Few genes have been implicated in sporadic premature ovarian failure. This study implicates STAG3, which encodes a cohesin, a protein that mediates chromosome…”
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Oxytocin receptor agonist reduces perinatal brain damage by targeting microglia
Published in Glia (01-02-2019)“…Prematurity and fetal growth restriction (FGR) are frequent conditions associated with adverse neurocognitive outcomes. We have previously identified early…”
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Sperm SPACA6 protein is required for mammalian Sperm-Egg Adhesion/Fusion
Published in Scientific reports (24-03-2020)“…Three genes are known to be essential for gamete adhesion/fusion ( Cd9, Izumo1 and Juno ). Here, we confirmed that Spaca6 null males are infertile and showed…”
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Pregnancy exposure to phthalates and DNA methylation in male placenta — An epigenome-wide association study
Published in Environment international (01-02-2022)“…[Display omitted] Exposure to phthalates during pregnancy may alter DNA methylation in the placenta, a crucial organ for the growth and development of the…”
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14
An integrated multi-tissue approach for endometriosis candidate biomarkers: a systematic review
Published in Reproductive biology and endocrinology (10-02-2024)“…Biomarker identification could help in deciphering endometriosis pathophysiology in addition to their use in the development of non invasive diagnostic and…”
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Long-term cardiovascular disorders in the STOX1 mouse model of preeclampsia
Published in Scientific reports (15-08-2019)“…Adverse long-term cardiovascular (CV) consequences of PE are well established in women. However, the mechanism responsible for that risk remains unknown. Here,…”
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A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse
Published in PLoS genetics (01-09-2012)“…Intragenomic conflicts arise when a genetic element favours its own transmission to the detriment of others. Conflicts over sex chromosome transmission are…”
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Hepatic transcriptome and DNA methylation patterns following perinatal and chronic BPS exposure in male mice
Published in BMC genomics (09-12-2020)“…Bisphenol S (BPS) is a common bisphenol A (BPA) substitute, since BPA is virtually banned worldwide. However, BPS and BPA have both endocrine disrupting…”
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Functional screening of TLRs in human amniotic epithelial cells
Published in The Journal of immunology (1950) (01-09-2011)“…Intrauterine infection is a major cause of spontaneous preterm birth. Amniotic epithelial cells represent the first line of defense against intra-amniotic…”
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Specific epigenetic alterations of IGF2-H19 locus in spermatozoa from infertile men
Published in European journal of human genetics : EJHG (01-01-2010)“…DNA methylation marks, a key modification of imprinting, are erased in primordial germ cells and sex specifically re-established during gametogenesis. Abnormal…”
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Preeclampsia induced by STOX1 overexpression in mice induces intrauterine growth restriction, abnormal ultrasonography and BOLD MRI signatures
Published in Journal of hypertension (01-06-2018)“…Preeclampsia is a major hypertensive disease caused by pregnancy, inducing proteinuria and increased blood pressure starting from the second half of pregnancy…”
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