Search Results - "Vaidya, Milind M."

Understanding the role of keratins 8 and 18 in neoplastic potential of breast cancer derived cell lines by Iyer, Sapna V, Dange, Prerana P, Alam, Hunain, Sawant, Sharada S, Ingle, Arvind D, Borges, Anita M, Shirsat, Neelam V, Dalal, Sorab N, Vaidya, Milind M

“…Breast cancer is a complex disease which cannot be defined merely by clinical parameters like lymph node involvement and histological grade, or by routinely…”
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Novel function of keratins 5 and 14 in proliferation and differentiation of stratified epithelial cells by Alam, Hunain, Sehgal, Lalit, Kundu, Samrat T, Dalal, Sorab N, Vaidya, Milind M

“…Keratins are cytoplasmic intermediate filament proteins preferentially expressed by epithelial tissues in a site-specific and differentiation-dependent manner…”
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Differential Ratios of Omega Fatty Acids (AA/EPA+DHA) Modulate Growth, Lipid Peroxidation and Expression of Tumor Regulatory MARBPs in Breast Cancer Cell Lines MCF7 and MDA-MB-231 by Mansara, Prakash P, Deshpande, Rashmi A, Vaidya, Milind M, Kaul-Ghanekar, Ruchika

“…Omega 3 (n3) and Omega 6 (n6) polyunsaturated fatty acids (PUFAs) have been reported to exhibit opposing roles in cancer progression. Our objective was to…”
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Multifaceted role of keratins in epithelial cell differentiation and transformation by Dmello, Crismita, Srivastava, Saumya S, Tiwari, Richa, Chaudhari, Pratik R, Sawant, Sharada, Vaidya, Milind M

“…Keratins, the epithelial-predominant members of the intermediate filament superfamily, are expressed in a pairwise, tissue-specific and…”
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Fascin overexpression promotes neoplastic progression in oral squamous cell carcinoma by Alam, Hunain, Bhate, Amruta V, Gangadaran, Prakash, Sawant, Sharda S, Salot, Shimul, Sehgal, Lalit, Dange, Prerana P, Chaukar, Devendra A, D'cruz, Anil K, Kannanl, Sadhna, Gude, Rajiv, Kane, Shubhada, Dalal, Sorab N, Vaidya, Milind M

“…Fascin is a globular actin cross-linking protein, which plays a major role in forming parallel actin bundles in cell protrusions and is found to be associated…”
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Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis by Khapare, Nileema, Kundu, Samrat T, Sehgal, Lalit, Sawant, Mugdha, Priya, Rashmi, Gosavi, Prajakta, Gupta, Neha, Alam, Hunain, Karkhanis, Madhura, Naik, Nishigandha, Vaidya, Milind M, Dalal, Sorab N

“…The desmosome anchors keratin filaments in epithelial cells leading to the formation of a tissue wide IF network. Loss of the desmosomal plaque protein…”
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Loss of keratin 8 phosphorylation leads to increased tumor progression and correlates with clinico-pathological parameters of OSCC patients by Alam, Hunain, Gangadaran, Prakash, Bhate, Amruta V, Chaukar, Devendra A, Sawant, Sharada S, Tiwari, Richa, Bobade, Jyoti, Kannan, Sadhana, D'cruz, Anil K, Kane, Shubhada, Vaidya, Milind M

“…Keratins are cytoplasmic intermediate filament proteins expressed in tissue specific and differentiation dependent manner. Keratins 8 and 18 (K8 and K18) are…”
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4-Nitroquinoline-1-oxide induced experimental oral carcinogenesis by Kanojia, Deepak, Vaidya, Milind M.

“…Human oral cancer is the sixth largest group of malignancies worldwide and single largest group of malignancies in the Indian subcontinent. Seventy percent of…”
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Prognostic value of tissue polypeptide antigen in oral squamous cell carcinoma by Sawant, Sharada S, Chaukar, Devendra A, Joshi, Shreyas S, Dange, Prerana P, Kannan, Sadhana, Kane, Shubhada, D’Cruz, Anil K, Vaidya, Milind M

“…Summary Human oral cancer has a high risk of locoregional relapse which is difficult to diagnose early due to lack of prognostic markers. We and others have…”
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Functional Implications of O-GlcNAcylation-dependent Phosphorylation at a Proximal Site on Keratin 18 by Kakade, Poonam S., Budnar, Srikanth, Kalraiya, Rajiv D., Vaidya, Milind M.

“…Keratins 8/18 (K8/18) are phosphoglycoproteins and form the major intermediate filament network of simple epithelia. The three O-GlcNAcylation (Ser29, Ser30,…”
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O-GlcNAcylation Determines the Solubility, Filament Organization, and Stability of Keratins 8 and 18 by Srikanth, Budnar, Vaidya, Milind M., Kalraiya, Rajiv D.

“…Keratins 8 and 18 (K8/18) are intermediate filament proteins expressed specifically in simple epithelial tissues. Dynamic equilibrium of these…”
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Loss of keratins 8 and 18 leads to alterations in α6β4-integrin-mediated signalling and decreased neoplastic progression in an oral-tumour-derived cell line by Alam, Hunain, Kundu, Samrat T, Dalal, Sorab N, Vaidya, Milind M

“…Keratins 8 and 18 (K8 and K18) are predominantly expressed in simple epithelial tissues and perform both mechanical and regulatory functions. Aberrant…”
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Generation of a tissue‐specific transgenic model for K8 phosphomutants: A tool to investigate the role of K8 phosphorylation during skin carcinogenesis in vivo by Tiwari, Richa, Ganguli, Nirmalya, Alam, Hunain, Sahu, Indrajit, Vadivel, Chella Krishna, Sinha, Shruti, Patel, Shweta, Jamghare, Sayli Nitin, Bane, Sanjay, Thorat, Rahul, Majumdar, Subeer S., Vaidya, Milind M.

“…Keratin 8/18, the predominant keratin pair of simple epithelia, is known to be aberrantly expressed in several squamous cell carcinomas (SCCs), where its…”
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Quantitative phosphoproteomic analysis reveals system‐wide signaling pathways regulated by site‐specific phosphorylation of Keratin‐8 in skin squamous cell carcinoma derived cell line by Tiwari, Richa, Sahu, Indrajit, Soni, Bihari lal, Sathe, Gajanan J., Datta, Keshava K., Thapa, Pankaj, Sinha, Shruti, Vadivel, Chella Krishna, Dhaka, Bharti, Gowda, Harsha, Vaidya, Milind M.

“…Keratin 8/18, a simple epithelia specific keratin pair, is often aberrantly expressed in squamous cell carcinomas (SCC) where its expression is correlated with…”
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Depletion of keratin 8/18 modulates oncogenic potential by governing multiple signaling pathways by Tiwari, Richa, Sahu, Indrajit, Soni, Bihari Lal, Sathe, Gajanan J, Thapa, Pankaj, Patel, Pavan, Sinha, Shruti, Vadivel, Chella Krishna, Patel, Shweta, Jamghare, Sayli Nitin, Oak, Swapnil, Thorat, Rahul, Gowda, Harsha, Vaidya, Milind M.

“…Keratin 8/18, the predominant keratin pair of simple epithelia, is often aberrantly expressed in various squamous cell carcinomas (SCCs) including skin SCC…”
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Keratin 5/14‑mediated cell differentiation and transformation are regulated by TAp63 and Notch‑1 in oral squamous cell carcinoma‑derived cells by Srivastava, Saumya S, Alam, Hunain, Patil, Sonam J, Shrinivasan, Rashmi, Raikundalia, Sweta, Chaudhari, Pratik Rajeev, Vaidya, Milind M

“…Keratins 5/14 (K5/14) are intermediate filament proteins expressed in the basal layer of stratified epithelial cells and are known targets of p63. Previous…”
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Versatile hemidesmosomal linker proteins: structure and function by Chaudhari, Pratik R, Vaidya, Milind M

“…Hemidesmosomes are anchoring junctions which connect basal epidermal cells to the extracellular matrix. In complex epithelia like skin, hemidesmosomes are…”
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Magnetic properties of LiZnCu ferrite synthesized by the microwave sintering method by Khot, Sujata S., Shinde, Neelam S., Basavaiah, Nathani, Watawe, Shrikant C., Vaidya, Milind M.

“…Lithium ferrites have attracted considerable attention because they have been used as replacements for garnets due to their low cost. A series of…”
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Identification of morphological and biochemical changes in keratin‐8/18 knock‐down cells using Raman spectroscopy by Singh, S. P., Alam, Hunain, Dmello, Crismita, Mamgain, Hitesh, Vaidya, Milind M., Dasari, Ramachandra Rao, Krishna, C. Murali

“…Accurate understanding of cellular processes and responses to stimuli is of paramount importance in biomedical research and diagnosis. Raman spectroscopy (RS),…”
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Inside Front Cover: Quantitative phosphoproteomic analysis reveals system‐wide signaling pathways regulated by site‐specific phosphorylation of Keratin‐8 in skin squamous cell carcinoma derived cell‐line by Tiwari, Richa, Sahu, Indrajit, Soni, Bihari lal, Sathe, Gajanan J., Datta, Keshava K., Thapa, Pankaj, Sinha, Shruti, Vadivel, Chella Krishna, Dhaka, Bharti, Gowda, Harsha, Vaidya, Milind M.

“…DOI: 10.1002/pmic.201600254 Phosphorylation is a major regulator of Keratin 8 canonical functions but its role in skin squamous cell carcinoma and the…”
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