Search Results - "Vaidya, Kalindi S."
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1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI)
Published in Bioorganic & medicinal chemistry letters (20-08-2001)“…1,4-Disubstituted imidazole inhibitors of Staphylococcus aureus and Escherichia coli enoyl acyl carrier protein reductase (FabI) have been identified. Crystal…”
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2-Aminomethyl piperidines as novel urotensin-II receptor antagonists
Published in Bioorganic & medicinal chemistry (01-05-2008)“…A series of 2-aminomethyl piperidines has been discovered as novel urotensin-II receptor antagonists. The synthesis, initial structure-activity relationships,…”
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Automated assay optimization with integrated statistics and smart robotics
Published in Journal of biomolecular screening (01-08-2000)“…The transition from manual to robotic high throughput screening (HTS) in the last few years has made it feasible to screen hundreds of thousands of chemical…”
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Potent and Selective Nonpeptide Inhibitors of Caspases 3 and 7 Inhibit Apoptosis and Maintain Cell Functionality
Published in The Journal of biological chemistry (26-05-2000)“…Caspases have been strongly implicated to play an essential role in apoptosis. A critical question regarding the role(s) of these proteases is whether…”
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