Search Results - "Vaher, Kadi"
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Cocaine-induced changes in behaviour and DNA methylation in rats are influenced by inter-individual differences in spontaneous exploratory activity
Published in Journal of psychopharmacology (Oxford) (01-06-2020)“…Background: Individual differences in behavioural traits influence susceptibility to addictive disorders. Drug addiction involves changes in gene expression,…”
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Breast Milk Exposure is Associated With Cortical Maturation in Preterm Infants
Published in Annals of neurology (01-03-2023)“…Objective Breast milk exposure is associated with improved neurocognitive outcomes following preterm birth but the neural substrates linking breast milk with…”
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3
General factors of white matter microstructure from DTI and NODDI in the developing brain
Published in NeuroImage (Orlando, Fla.) (01-07-2022)“…Preterm birth is closely associated with diffuse white matter dysmaturation inferred from diffusion MRI and neurocognitive impairment in childhood. Diffusion…”
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Feature similarity gradients detect alterations in the neonatal cortex associated with preterm birth
Published in Human brain mapping (01-03-2024)“…The early life environment programmes cortical architecture and cognition across the life course. A measure of cortical organisation that integrates…”
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5
Associations between alcohol use and accelerated biological ageing
Published in Addiction biology (01-01-2022)“…Harmful alcohol use is a leading cause of premature death and is associated with age‐related disease. Biological ageing is highly variable between individuals…”
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Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn
Published in BMC research notes (03-08-2020)“…To determine if fermented soy supplementation relieves heartburn and improves gastrointestinal symptoms and quality of life, a randomized, double-blind…”
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7
Infant attachment does not depend on neonatal amygdala and hippocampal structure and connectivity
Published in Developmental cognitive neuroscience (01-06-2024)“…Infant attachment is an antecedent of later socioemotional abilities, which can be adversely affected by preterm birth. The structural integrity of amygdalae…”
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Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles
Published in Genome medicine (04-01-2021)“…The apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late onset Alzheimer's disease, whilst the ε2 allele confers protection…”
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9
Epigenetic scores derived in saliva are associated with gestational age at birth
Published in Clinical epigenetics (29-06-2024)“…Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins…”
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Epigenome‐wide analyses identify DNA methylation signatures of dementia risk
Published in Alzheimer's & dementia : diagnosis, assessment & disease monitoring (2020)“…Introduction Dementia pathogenesis begins years before clinical symptom onset, necessitating the understanding of premorbid risk mechanisms. Here we…”
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Microbiome-gut-brain axis in brain development, cognition and behavior during infancy and early childhood
Published in Developmental review (01-12-2022)“…•Brain and gut microbiome develop rapidly in parallel during the first years of life.•20 studies link gut microbiome diversity/composition with typical…”
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Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters
Published in Molecular psychiatry (01-07-2022)“…Growing evidence supports a role for deficient Wnt signalling in Alzheimer’s disease (AD). First, the Wnt antagonist DKK1 is elevated in AD brains and is…”
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Immuno-epigenetic signature derived in saliva associates with the encephalopathy of prematurity and perinatal inflammatory disorders
Published in Brain, behavior, and immunity (01-05-2023)“…[Display omitted] •DNA methylation signature of inflammation derived in neonatal saliva samples.•Preterm infants display higher inflammatory-related DNAm than…”
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Preterm infant attachment is independent of breast milk intake during neonatal care
Published in Wellcome open research (2024)“…Background Following preterm birth, breast milk feeding is recommended because it confers broad health benefits to preterm infants. Breast milk has been…”
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Fermented Soy Supplementation Improves Quality of Life Indicators: A Randomized, Placebo-Controlled, Double-Blind Trial in Adults Experiencing Heartburn
Published in Current developments in nutrition (01-06-2020)“…The aim of this pilot study was to determine the effects of a fermented soy supplement on heartburn relief, gastrointestinal symptoms, and quality of life. A…”
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Association of Preterm Birth and Socioeconomic Status With Neonatal Brain Structure
Published in JAMA network open (01-05-2023)“…Preterm birth and socioeconomic status (SES) are associated with brain structure in childhood, but the relative contributions of each during the neonatal…”
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Identification of epigenome-wide DNA methylation differences between carriers of APOE [epsilon]4 and APOE [epsilon]2 alleles
Published in Genome medicine (04-01-2021)“…Background The apolipoprotein E (APOE) [epsilon]4 allele is the strongest genetic risk factor for late onset Alzheimer's disease, whilst the [epsilon]2 allele…”
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18
Characterisation of the neonatal brain using myelin-sensitive magnetisation transfer imaging
Published in Imaging neuroscience (Cambridge, Mass.) (12-09-2023)“…Abstract A cardinal feature of the encephalopathy of prematurity is dysmaturation of developing white matter and subsequent hypomyelination. Magnetisation…”
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