Search Results - "Vaerman, J.‐P."

Lung mucosal immunity: immunoglobulin-A revisited by Pilette, C, Ouadrhiri, Y, Godding, V, Vaerman, J-P, Sibille, Y

“…Mucosal defence mechanisms are critical in preventing colonization of the respiratory tract by pathogens and penetration of antigens through the epithelial…”
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Increased galectin-3 expression and intra-epithelial neutrophils in small airways in severe COPD by Pilette, C, Colinet, B, Kiss, R, Andre, S, Kaltner, H, Gabius, H-J, Delos, M, Vaerman, J-P, Decramer, M, Sibille, Y

“…Galectins-1 and -3 regulate epithelial proliferation/apoptosis and neutrophil activation, and are implicated in lung cancer and asthma. The role of galectins…”
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Human antibody response to Clostridium difficile toxin A in relation to clinical course of infection by WARNY, M, VAERMAN, J.-P, AVESANI, V, DELMEE, M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Oxidative burst in lipopolysaccharide-activated human alveolar macrophages is inhibited by interleukin-9 by Pilette, C, Ouadrhiri, Y, Van Snick, J, Renauld, J-C, Staquet, P, Vaerman, J-P, Sibille, Y

“…Interleukin (IL)-9 is known to regulate many cell types involved in T-helper type 2 responses classically associated with asthma, including B- and…”
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Reduced epithelial expression of secretory component in small airways correlates with airflow obstruction in chronic obstructive pulmonary disease by PILETTE, Charles, GODDING, Veronique, KISS, Robert, DELOS, Monique, VERBEKEN, Eric, DECAESTECKER, Christine, DE PAEPE, Kristel, VAERMAN, Jean-Pierre, DECRAMER, Marc, SIBILLE, Yves

“…The epithelial polymeric immunoglobulin receptor/transmembrane secretory component (pIgR/SC) transports into secretions polymeric immunoglobulin A (pIgA),…”
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Polymeric IgA Binding to the Human pIgR Elicits Intracellular Signalling, but Fails to Stimulate pIgR‐Transcytosis by Giffroy, D., Courtoy, P.‐J., Vaerman, J.‐P.

“…The intracellular pathway of polymeric immunoglobulin receptor (pIgR) is governed by multiple signals that lead to constitutive transcytosis. In addition, in…”
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Stimulation of Transcytosis of the Polymeric Immunoglobulin Receptor by Dimeric IgA by Song, Wenxia, Bomsel, Morgane, Casanova, James, Vaerman, Jean-Pierre, Mostov, Keith

“…The polymeric immunoglobulin receptor (pIgR) is transcytosed from the basolateral to the apical surface of polarized epithelial cells. We have previously shown…”
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The Polymeric Immunoglobulin Receptor (Secretory Component) Mediates Transport of Immune Complexes Across Epithelial Cells: A Local Defense Function for IgA by Kaetzel, Charlotte S., Robinson, Janet K., Chintalacharuvu, Koteswara R., Vaerman, Jean-Pierre, Lamm, Michael E.

“…The polymeric immunoglobulin receptor (pIgR) on mucosal epithelial cells binds dimeric IgA (dIgA) on the basolateral surface and mediates transport of dIgA to…”
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Stimulation of secretory IgA and secretory component of immunoglobulins in small intestine of rats treated with Saccharomyces boulardii by BUTS, J.-P, BERNASCONI, P, VAERMAN, J.-P, DIVE, C

“…Saccharomyces boulardii (S.b.) is largely used in Western European countries for the treatment of acute infectious enteritis and antibiotic-induced…”
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Secretory component production by human bronchial epithelial cells is upregulated by interferon gamma by Godding, V, Sibille, Y, Massion, PP, Delos, M, Sibille, C, Thurion, P, Giffroy, D, Langendries, A, Vaerman, JP

“…Secretory immunoglobulin A (S-IgA) participates in the first noninflammatory line of defence of the respiratory tract. S-IgA consists of dimeric IgA (dIgA)…”
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Lack of SC/pIgR‐mediated epithelial transport of a human polymeric IgA devoid of J chain: in vitro and in vivo studies by Vaerman, J P, Langendries, A, Giffroy, D, Brandtzaeg, P, Kobayashi, K

“…Three human polymeric IgA (pIgA) myeloma proteins of tetrameric size were compared for their J‐chain content, their in vitro secretory component (SC)‐binding…”
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Differential effects of the T helper cell type 2-derived cytokines IL-4 and IL-5 on ligand binding to IgG and IgA receptors expressed by human eosinophils by Bracke, M, Dubois, GR, Bolt, K, Bruijnzeel, PL, Vaerman, JP, Lammers, JW, Koenderman, L

“…Increased numbers of eosinophilic granulocytes that exhibit an activated phenotype are found in bronchial tissue and bronchial alveolar lavage fluid of…”
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Influence of severe protein malnutrition on rat lacrimal, salivary and gastrointestinal immune expression during development, adulthood and ageing by SULLIVAN, D. A, VAERMAN, J.-P, SOO, C

“…The objective of the present study was to examine and to compare the impact of severe protein malnutrition during development, adulthood and ageing on…”
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Neuroendocrinimmune modulation of secretory component production by rat lacrimal, salivary, and intestinal epithelial cells by Lambert, RW, Kelleher, RS, Wickham, LA, Vaerman, JP, Sullivan, DA

“…To evaluate the kinetics, receptor specificity, molecular basis, and site selectivity of the endocrine and neural regulation of secretory component (SC)…”
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Evaluation of monoclonal antibodies with specificity of human IgA, IgA subclasses and allotypes and secretory component results of an IUIS/WHO collaborative study by Mestecky, J., Hamilton, R.G., Magnusson, C.G.M., Jefferis, R., Vaerman, J.P., Goodall, M., de Lange, G.G., Moro, I., Aucouturier, P., Radl, J., Cambiaso, C., Silvain, C., Preud'homme, J.L., Kusama, K., Carlone, G.M., Biewenga, J., Kobayashi, K., Skvaril, F., Reimer, C.B.

“…51 monoclonal antibodies (McAb) with putative specificity for human IgA, the IgA subclasses, Am allotypes or secretory component (SC) were evaluated for…”
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Antibody against the human J chain inhibits polymeric Ig receptor‐mediated biliary and epithelial transport of human polymeric IgA by Vaerman, Jean‐Pierre, Langendries, Agnes E., Giffroy, Didier A., Kaetzel, Charlotte S., Tamer Fiani, Carol M., Moro, Itaru, Brandtzaeg, Per, Kobayashi, Kunihiko

“…To emphasize the requirement for a J chain in native polymeric immunoglobulins for their selective transport into exocrine secretions, IgG, purified from two…”
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Secretion of immunoglobulins and plasma proteins from the colonic mucosa: an in vivo study in man by PRIGENT‐DELECOURT, L., COFFIN, B., COLOMBEL, J. F., DEHENNIN, J. P., VAERMAN, J. P, RAMBAUD, J. C.

“…SUMMARY There are no available data on immunoglobulins and albumin outputs into the normal human colon. We thus measured the intracolonic secretion rates of…”
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In vivo stimulation of polymeric Ig receptor transcytosis by circulating polymeric IgA in rat liver by Giffroy, D, Langendries, A, Maurice, M, Daniel, F, Lardeux, B, Courtoy, P J, Vaerman, J P

“…Binding of human polymeric IgA ligand to its epithelial cell polymeric Ig receptor, pIgR, has been shown to stimulate pIgR apical transcytosis in an in vitro…”
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Characterization of an IgA receptor from group B streptococci: specificity for serum IgA by Lindahl, G, Akerström, B, Vaerman, J P, Stenberg, L

“…Some strains of group B streptococci express a cell surface protein which binds IgA. This report describes some properties of such an IgA receptor and compares…”
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Dimeric and tetrameric IgA are transcytosed equally by the polymeric Ig receptor by Song, W, Vaerman, JP, Mostov, KE

“…Polymeric IgA (pIgA) is transcytosed across epithelial cells and into external secretions by the polymeric Ig receptor (pIgR). Binding of dimeric IgA (dIgA) to…”
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