Search Results - "Vader, P."

Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy by Jiang, L, Vader, P, Schiffelers, R M

“…Nucleic acid-based drugs offer a potentially effective tool for treatment of a variety of diseases, including cancer, cardiovascular diseases, neurological…”
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PEGylated and targeted extracellular vesicles display enhanced cell specificity and circulation time by Kooijmans, S.A.A., Fliervoet, L.A.L., van der Meel, R., Fens, M.H.A.M., Heijnen, H.F.G., van Bergen en Henegouwen, P.M.P., Vader, P., Schiffelers, R.M.

“…Extracellular vesicles (EVs) are increasingly being recognized as candidate drug delivery systems due to their ability to functionally transfer biological…”
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Surgery in lumbar degenerative spondylolisthesis: indications, outcomes and complications. A systematic review by Steiger, F., Becker, H.-J., Standaert, C. J., Balague, F., Vader, J.-P., Porchet, F., Mannion, A. F.

“…Purpose This systematic review summarises the literature on patient selection, decision-making, effectiveness and outcomes in the surgical treatment of lumbar…”
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Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions by van Doormaal, J. J., van der Veer, E., van Voorst Vader, P. C., Kluin, P. M., Mulder, A. B., van der Heide, S., Arends, S., Kluin-Nelemans, J. C., Oude Elberink, J. N. G., de Monchy, J. G. R.

“…Background Risk indicators of indolent systemic mastocytosis (ISM) in adults with clinical suspicion of ISM without accompanying skin lesions [urticaria…”
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Influence of short term storage conditions, concentration methods and excipients on extracellular vesicle recovery and function by van de Wakker, S.I., van Oudheusden, J., Mol, E.A., Roefs, M.T., Zheng, W., Görgens, A., El Andaloussi, S., Sluijter, J.P.G., Vader, P.

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The gap between scientific evidence and clinical practice: 5‐aminosalicylates are frequently used for the treatment of Crohn's disease by Schoepfer, A. M., Bortolotti, M., Pittet, V., Mottet, C., Gonvers, J.‐J., Reich, O., Fournier, N., Vader, J.‐P., Burnand, B., Michetti, P., Froehlich, F.

“…Summary Background There is uncertain evidence of effectiveness of 5‐aminosalicylates (5‐ASA) to induce and maintain response and remission of active Crohn's…”
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Cardiac delivery of modified mRNA using lipid nanoparticles: Cellular targets and biodistribution after intramyocardial administration by Labonia, M.C.I., Estapé Senti, M., van der Kraak, P.H., Brans, M.A.D., Dokter, I., Streef, T.J., Smits, A.M., Deshantri, A.K., de Jager, S.C.A., Schiffelers, R.M., Sluijter, J.P.G., Vader, P.

“…Despite research efforts being made towards preserving (or even regenerating) heart tissue after an ischemic event, there is a lack of resources in current…”
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Recommendations for treatment of lymphomatoid papulosis with methotrexate: a report from the Dutch Cutaneous Lymphoma Group by Bruijn, M.S., Horváth, B., van Voorst Vader, P.C., Willemze, R., Vermeer, M.H.

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IUSTI: 2008 European Guidelines on the Management of Syphilis by French, P, Gomberg, M, Janier, M, Schmidt, B, van Voorst Vader, P, Young, H

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Influence of short term storage conditions, concentration methodsand excipients on extracellular vesicle recovery and function by van de Wakker, S.I., van Oudheusden, J., Mol, E.A., Roefs, M.T., Zheng, W., Görgens, A., El Andaloussi, S., Sluijter, J.P.G., Vader, P.

“…[Display omitted] Extracellular vesicles (EVs) are phospholipid bilayer enclosed vesicles which play an important role in intercellular communication. To date,…”
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Development of appropriateness criteria for the surgical treatment of symptomatic lumbar degenerative spondylolisthesis (LDS) by Mannion, A. F., Pittet, V., Steiger, F., Vader, J.-P., Becker, H.-J., Porchet, F.

“…Purpose Spine surgery rates are increasing worldwide. Treatment failures are often attributed to poor patient selection and inappropriate treatment, but for…”
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Optimization of poly(amido amine)s as vectors for siRNA delivery by van der Aa, L.J., Vader, P., Storm, G., Schiffelers, R.M., Engbersen, J.F.J.

“…By Michael addition polymerization of N,N'-cystaminebisacrylamide (CBA) with variable ratios of 4-amino-1-butanol (ABOL) and ethylene diamine (EDA) or…”
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Polymeric carrier systems for siRNA delivery by Vader, P, van der Aa, L J, Storm, G, Schiffelers, R M, Engbersen, J F J

“…RNA interference is a technique to induce sequence-specific gene silencing, but is hampered by inefficient delivery of its mediator, short interfering RNA,…”
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Targeted delivery of small interfering RNA to angiogenic endothelial cells with liposome-polycation-DNA particles by Vader, P., Crielaard, B.J., van Dommelen, S.M., van der Meel, R., Storm, G., Schiffelers, R.M.

“…Angiogenesis is an attractive target for cancer therapy, due to its central position in tumor growth and development. Vascular Endothelial Growth Factor (VEGF)…”
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Appropriateness of colonoscopy in Europe (EPAGE II). Screening for colorectal cancer by Arditi, C, Peytremann-Bridevaux, I, Burnand, B, Eckardt, V F, Bytzer, P, Agréus, L, Dubois, R W, Vader, J-P, Froehlich, F, Pittet, V, Schusselé Filliettaz, S, Juillerat, P, Gonvers, J-J

“…To summarize the published literature on assessment of appropriateness of colonoscopy for screening for colorectal cancer (CRC) in asymptomatic individuals…”
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Intercalating quaternary nicotinamide-based poly(amido amine)s for gene delivery by van der Aa, L.J., Vader, P., Storm, G., Schiffelers, R.M., Engbersen, J.F.J.

“…In the development of potent polymeric gene carriers for gene therapy, a good interaction between the polymer and the nucleotide is indispensable to form small…”
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Appropriateness of colonoscopy in Europe (EPAGE II). Presentation of methodology, general results, and analysis of complications by Juillerat, P, Peytremann-Bridevaux, I, Vader, J-P, Arditi, C, Schusselé Filliettaz, S, Dubois, R W, Gonvers, J-J, Froehlich, F, Burnand, B, Pittet, V

“…Appropriate use of colonoscopy is a key component of quality management in gastrointestinal endoscopy. In an update of a 1998 publication, the 2008 European…”
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Contribution of highly sensitive diagnostic methods to the diagnosis of systemic mastocytosis in the absence of skin lesions by Alvarez-Twose, I., Matito, A., Sánchez-Muñoz, L., Morgado, J. M., Orfao, A., Escribano, L., van Doormaal, J. J., van der Veer, E., van Voorst Vader, P. C., Kluin, P. M., Mulder, A. B., van der Heide, S., Arends, S., Kluin-Nelemans, J. C., Oude Elberink, J. N. G., de Monchy, J. G. R.

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Current sedation and monitoring practice for colonoscopy: an International Observational Study (EPAGE) by Froehlich, F, Harris, J K, Wietlisbach, V, Burnand, B, Vader, J-P, Gonvers, J-J

“…Sedation and monitoring practice during colonoscopy varies between centers and over time. Knowledge of current practice is needed to ensure quality of care and…”
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448 Exposure to EGFR inhibitors influences release of extracellular vesicles by tumor cells by van der Meel, R, van Dommelen, S.M, de Corte, P, Coimbra, M, van Solinge, W.W, Vader, P, Schiffelers, R.M

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