Search Results - "Vadalà, Gianluca"
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Intervertebral disc degeneration: A focus on obesity and type 2 diabetes
Published in Diabetes/metabolism research and reviews (01-01-2020)“…Summary Obesity (OB) and type 2 diabetes (T2D) are among the most prevalent metabolic diseases. They currently affect a substantial part of the world…”
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Interaction between Mesenchymal Stem Cells and Intervertebral Disc Microenvironment: From Cell Therapy to Tissue Engineering
Published in Stem cells international (2019)“…Low back pain (LBP) in one of the most disabling symptoms affecting nearly 80% of the population worldwide. Its primary cause seems to be intervertebral disc…”
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Anterior Cruciate Ligament Repair Augmented With Dynamic Intraligamentary Stabilization Is Equivalent to Hamstring Autograft Reconstruction at Short- and Mid-Term Follow-Up: A Systematic Review
Published in Arthroscopy (01-07-2024)“…To compare clinical outcomes, knee stability and complications, failure, and revision rates after anterior cruciate ligament repair (ACLr) with dynamic…”
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Invasive Intraneural Interfaces: Foreign Body Reaction Issues
Published in Frontiers in neuroscience (06-09-2017)“…Intraneural interfaces are stimulation/registration devices designed to couple the peripheral nervous system (PNS) with the environment. Over the last years,…”
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Innovative Biomaterials for the Treatment of Bone Cancer
Published in International journal of molecular sciences (30-07-2021)“…Bone cancer is a demanding challenge for contemporary medicine due to its high frequency of presentation and significant heterogeneity of malignant lesions…”
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Osteoarthritis and type 2 diabetes: From pathogenetic factors to therapeutic intervention
Published in Diabetes/metabolism research and reviews (01-03-2020)“…Summary Over the last decades, osteoarthritis (OA) and type 2 diabetes (T2D) prevalence increased due to the global ageing population and the pandemic obesity…”
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Platelet Rich Plasma and Hyaluronic Acid Blend for the Treatment of Osteoarthritis: Rheological and Biological Evaluation
Published in PloS one (16-06-2016)“…Osteoarthritis (OA) is the most common musculoskeletal disease. Current treatments for OA are mainly symptomatic and inadequate since none results in…”
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COVID-19 Pandemic Increases the Impact of Low Back Pain: A Systematic Review and Metanalysis
Published in International journal of environmental research and public health (11-04-2022)“…In March 2019, the World Health Organization (WHO) recognized the COVID-19 pandemic as a global issue. To reduce the spread of this disease, health safety…”
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Effect of Irisin on Human Nucleus Pulposus Cells: New Insights into the Biological Cross-talk Between Muscle and Intervertebral Disk
Published in Spine (Philadelphia, Pa. 1976) (01-04-2023)“…In vitro study. To investigate the effect of irisin on human nucleus pulposus cells (hNPCs) in vitro. Physical exercise (PE) favours weight loss and…”
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Sclerostin Regulation, Microarchitecture, and Advanced Glycation End‐Products in the Bone of Elderly Women With Type 2 Diabetes
Published in Journal of bone and mineral research (01-12-2020)“…ABSTRACT Increased circulating sclerostin and accumulation of advanced glycation end‐products (AGEs) are two potential mechanisms underlying low bone turnover…”
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The Effects of Workplace Interventions on Low Back Pain in Workers: A Systematic Review and Meta-Analysis
Published in International journal of environmental research and public health (30-11-2021)“…This systematic review and meta-analysis aimed to analyze the effects of workplace interventions (WI) on clinical outcomes related to low back pain (LBP) in a…”
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Does Workers’ Compensation Status Affect Outcomes after Lumbar Spine Surgery? A Systematic Review and Meta-Analysis
Published in International journal of environmental research and public health (07-06-2021)“…Low back pain (LBP) is currently the leading cause of disability worldwide and the most common reason for workers’ compensation (WC) claims. Studies have…”
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Bone canonical Wnt signaling is downregulated in type 2 diabetes and associates with higher advanced glycation end-products (AGEs) content and reduced bone strength
Published in eLife (10-04-2024)“…Type 2 diabetes (T2D) is associated with higher fracture risk, despite normal or high bone mineral density. We reported that bone formation genes ( and ) and…”
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The Role of Type I Diabetes in Intervertebral Disc Degeneration
Published in Spine (Philadelphia, Pa. 1976) (01-09-2019)“…STUDY DESIGN.An experimental laboratory study. OBJECTIVE.To investigate the pathogenesis of intervertebral disc degeneration (IDD) in a murine model of type 1…”
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Previous lumbar spine fusion increases the risk of dislocation following total hip arthroplasty in patients with hip-spine syndrome: a systematic review and meta-analysis
Published in BMC musculoskeletal disorders (13-09-2024)“…With life expectancy on the rise, there has been an increase in patients with concomitant degenerative hip and spine pathology, defined as hip-spine syndrome…”
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Intervertebral disc regeneration: from the degenerative cascade to molecular therapy and tissue engineering
Published in Journal of tissue engineering and regenerative medicine (01-06-2015)“…Low back pain is one of the major health problems in industrialized countries, as a leading source of disability in the working population. Intervertebral disc…”
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Artificial Intelligence and Computer Vision in Low Back Pain: A Systematic Review
Published in International journal of environmental research and public health (17-10-2021)“…Chronic Low Back Pain (LBP) is a symptom that may be caused by several diseases, and it is currently the leading cause of disability worldwide. The increased…”
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The impact of type 2 diabetes on the development of tendinopathy
Published in Diabetes/metabolism research and reviews (01-09-2021)“…Tendinopathy is a chronic and often painful condition affecting both professional athletes and sedentary subjects. It is a multi‐etiological disorder caused by…”
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Safety and Complications Related to Emerging Technologies
Published in Neurospine (01-03-2024)“…KCI Citation Count: 0…”
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Use of an Antifibrotic Agent Improves the Effect of Platelet-Rich Plasma on Muscle Healing After Injury
Published in Journal of bone and joint surgery. American volume (05-06-2013)“…Muscle contusions are a common type of muscle injury and are frequently encountered in athletes and military personnel. Although these injuries are capable of…”
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