Search Results - "Vadakattu, Manasa"
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Fused-azepinones: Emerging scaffolds of medicinal importance
Published in European journal of medicinal chemistry (05-08-2021)“…Hymenialdisine an alkaloid of oroidin class has drawn the attention of researchers owing to its unique structural features and interesting biological…”
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Exploration of 1,3,5-trisubstituted pyrazoline derivatives as human carbonic anhydrase inhibitors: Synthesis, biological evaluation and in silico studies
Published in International journal of biological macromolecules (01-11-2024)“…The human carbonic anhydrase (hCA) IX and XII isoforms are overexpressed in hypoxic conditions, contributing to cancer. Lack of isoform selectivity has been…”
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Synthesis and biological evaluation of 1-phenyl-4,6-dihydrobenzo[b]pyrazolo[3,4-d]azepin-5(1H)-one/thiones as anticancer agents
Published in Bioorganic chemistry (01-06-2023)“…[Display omitted] •1-aryl-2,6-dihydrobenzo[b]pyrazolo[3,4-d]azepin-5(4H)-one/thiones were synthesized and screened against selected cancer cell…”
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Bacterial Pyruvate Kinase: A New Potential Target to Combat Drug‐Resistant Staphylococcus aureus Infections
Published in ChemistrySelect (Weinheim) (05-08-2022)“…Severity of Infections caused by Staphylococcus aureus ranges from trivial to spine chilling. Irrespective of multiple drugs availability to treat S. aureus…”
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Synthesis and Antibacterial Evaluation of 3,4‐Dihydro‐1H‐benzo[b]azepine‐2,5‐dione Derivatives
Published in ChemistrySelect (Weinheim) (18-02-2022)“…Fused‐azepinones are interesting heterocyclic scaffolds present in various natural products and synthetic derivatives with potent kinase inhibition,…”
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Synthesis and Antibacterial Evaluation of 3,4‐Dihydro‐1 H ‐benzo[ b ]azepine‐2,5‐dione Derivatives
Published in ChemistrySelect (Weinheim) (18-02-2022)“…Fused‐azepinones are interesting heterocyclic scaffolds present in various natural products and synthetic derivatives with potent kinase inhibition,…”
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