Search Results - "Vaculin, Bradley"
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Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway
Published in American Journal of Physiology: Cell Physiology (01-08-2008)“…Cholangiopathies are characterized by the heterogeneous proliferation of different-sized cholangiocytes. Large cholangiocytes proliferate by a cAMP-dependent…”
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H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway
Published in Laboratory investigation (01-05-2007)“…Histamine regulates many functions by binding to four histamine G-coupled receptor proteins (H1R, H2R, H3R and H4R). As H3R exerts their effects by coupling to…”
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Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth
Published in The Journal of biological chemistry (27-04-2007)“…Cholangiocarcinomas are devastating cancers of biliary origin with limited treatment options. Modulation of the endocannabinoid system is being targeted to…”
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Opposing Actions of Endocannabinoids on Cholangiocarcinoma Growth: RECRUITMENT OF Fas AND Fas LIGAND TO LIPID RAFTS
Published in The Journal of biological chemistry (27-04-2007)“…Cholangiocarcinomas are devastating cancers of biliary origin with limited treatment options. Modulation of the endocannabinoid system is being targeted to…”
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The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway
Published in American journal of physiology: Gastrointestinal and liver physiology (01-12-2008)“…Cholangiocarcinomas are cancers that have poor prognosis and limited treatment options. The noncanonical Wnt pathway is mediated predominantly by Wnt 5a, which…”
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Anandamide inhibits cholangiocyte hyperplastic proliferation via activation of thioredoxin 1/redox factor 1 and AP-1 activation
Published in American journal of physiology: Gastrointestinal and liver physiology (01-02-2008)“…The endocannabinoid system regulates various aspects of hepatic fibrosis; however, nothing is known about its role in regulating cholangiocyte proliferation…”
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Progesterone stimulates the proliferation of female and male cholangiocytes via autocrine/paracrine mechanisms
Published in American journal of physiology: Gastrointestinal and liver physiology (01-07-2008)“…During cholestatic liver diseases, cholangiocytes express neuroendocrine phenotypes and respond to a number of hormones and neuropeptides by paracrine and…”
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Differential Regulation of Cholangiocyte Growth by Activation of Different Histamine Receptor Subtypes
Published in The FASEB journal (2007)“…Histamine exerts its functions by binding to four histamine G‐coupled receptor proteins (H1R, H2R, H3R and H4R). Cross‐talk between Ca2+ and cAMP regulates…”
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Substance P Regulates Biliary Growth During Cholestasis Induced by Bile Duct Obstruction (BDL)
Published in The FASEB journal (2007)“…Liver diseases are characterized by bile duct damage requiring cholangiocyte growth to retain function. Substance P (SP)‐positive innervation surrounds the…”
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Thyroid hormone inhibits biliary growth in bile duct-ligated rats by PLC/IP(3)/Ca(2+)-dependent downregulation of SRC/ERK1/2
Published in American Journal of Physiology: Cell Physiology (01-04-2007)“…The role of the thyroid hormone agonist 3,3',5 l-tri-iodothyronine (T3) on cholangiocytes is unknown. We evaluated the in vivo and in vitro effects of T3 on…”
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Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca.sup.2+.sup.-dependent PKC isoforms
Published in BMC physiology (19-07-2007)Get full text
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Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca super(2+)-dependent PKC isoforms
Published in BMC physiology (01-01-2007)“…Background Prolactin promotes proliferation of several cells. Prolactin receptor exists as two isoforms: long and short, which activate different transduction…”
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Prolactin stimulates the proliferation of normal female cholangiocytes by differential regulation of Ca2+-dependent PKC isoforms
Published in BMC physiology (19-07-2007)“…Prolactin promotes proliferation of several cells. Prolactin receptor exists as two isoforms: long and short, which activate different transduction pathways…”
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