Search Results - "Vachon, CM"
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Risk of Breast Cancer With Oral Contraceptive Use in Women With a Family History of Breast Cancer
Published in JAMA : the journal of the American Medical Association (11-10-2000)“…CONTEXT Oral contraceptive (OC) use is weakly associated with breast cancer risk in the general population, but the association among women with a familial…”
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2
Case-Control Study of Increased Mammographic Breast Density Response to Hormone Replacement Therapy
Published in Cancer epidemiology, biomarkers & prevention (01-11-2002)“…Previous studies have demonstrated an association between current hormone replacement therapy (HRT) use and increased mammographic breast density. Many of…”
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Association of aspirin and other non‐steroidal anti‐inflammatory drug use with incidence of non‐hodgkin lymphoma
Published in International journal of cancer (20-09-2003)“…Non‐steroidal anti‐inflammatory drugs (NSAIDs), including aspirin, seem to have chemopreventive properties against several types of cancer, particularly colon…”
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Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Published in American journal of human genetics (2019)“…Stratification of women according to their risk of breast cancer based on polygenic risk scores (PRSs) could improve screening and prevention strategies. Our…”
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Prospective evaluation of a breast-cancer risk model integrating classical risk factors and polygenic risk in 15 cohorts from six countries
Published in International journal of epidemiology (06-01-2022)“…Abstract Background Rigorous evaluation of the calibration and discrimination of breast-cancer risk-prediction models in prospective cohorts is critical for…”
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6
Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk
Published in American journal of human genetics (05-11-2020)“…Previous research has shown that polygenic risk scores (PRSs) can be used to stratify women according to their risk of developing primary invasive breast…”
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Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study
Published in British journal of sports medicine (01-10-2022)“…Physical inactivity and sedentary behaviour are associated with higher breast cancer risk in observational studies, but ascribing causality is difficult…”
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Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia
Published in Nature genetics (01-08-2013)“…Susan Slager and colleagues report a meta-analysis of genome-wide association studies for chronic lymphocytic leukemia (CLL). They identify nine loci newly…”
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Meta-analysis of genome-wide association studies discovers multiple loci for chronic lymphocytic leukemia
Published in Nature communications (09-03-2016)“…Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and…”
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10
Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Published in Nature genetics (01-07-2024)“…Pubertal timing varies considerably and is associated with later health outcomes. We performed multi-ancestry genetic analyses on ~800,000 women, identifying…”
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11
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk
Published in Nature communications (24-10-2014)“…Mammographic density reflects the amount of stromal and epithelial tissues in relation to adipose tissue in the breast and is a strong risk factor for breast…”
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Breast Cancer Risk Factors and Survival by Tumor Subtype: Pooled Analyses from the Breast Cancer Association Consortium
Published in Cancer epidemiology, biomarkers & prevention (01-04-2021)“…It is not known whether modifiable lifestyle factors that predict survival after invasive breast cancer differ by subtype. We analyzed data for 121,435 women…”
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A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11
Published in Human molecular genetics (15-12-2012)“…Genome-wide association studies (GWAS) of breast cancer defined by hormone receptor status have revealed loci contributing to susceptibility of estrogen…”
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14
Incidence of Basal Cell and Squamous Cell Carcinomas in a Population Younger Than 40 Years
Published in JAMA : the journal of the American Medical Association (10-08-2005)“…CONTEXT The incidence of nonmelanoma skin cancer is increasing rapidly among elderly persons, but little is known about its incidence in the population younger…”
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15
A genome-wide association study of mammographic texture variation
Published in Breast cancer research : BCR (07-11-2022)“…Breast parenchymal texture features, including grayscale variation (V), capture the patterns of texture variation on a mammogram and are associated with breast…”
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International Pooled Analysis of Leisure-Time Physical Activity and Premenopausal Breast Cancer in Women From 19 Cohorts
Published in Journal of clinical oncology (2024)“…There is strong evidence that leisure-time physical activity is protective against postmenopausal breast cancer risk but the association with premenopausal…”
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17
Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci
Published in Breast cancer research : BCR (12-04-2022)“…Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dense tissue (NDA), are associated with…”
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Distinct germline genetic susceptibility profiles identified for common non-Hodgkin lymphoma subtypes
Published in Leukemia (01-12-2022)“…Lymphoma risk is elevated for relatives with common non-Hodgkin lymphoma (NHL) subtypes, suggesting shared genetic susceptibility across subtypes. To evaluate…”
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19
A network analysis to identify mediators of germline-driven differences in breast cancer prognosis
Published in Nature communications (16-01-2020)“…Identifying the underlying genetic drivers of the heritability of breast cancer prognosis remains elusive. We adapt a network-based approach to handle…”
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Common variants in breast cancer risk loci predispose to distinct tumor subtypes
Published in Breast cancer research : BCR (2022)“…Genome-wide association studies (GWAS) have identified multiple common breast cancer susceptibility variants. Many of these variants have differential…”
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