Search Results - "Vachaspati, Prakash R."

Fast mouse PK (Fast PK): A rapid screening method to increase pharmacokinetic throughput in pre-clinical drug discovery by Reddy, Jitendar, Madishetti, Sreedhar, Vachaspati, Prakash R.

“…We describe a rapid screening methodology for performing pharmacokinetic (PK) studies in mice called Fast PK. In this Fast PK method, two mice were used per…”
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Identification and characterisation of a novel amino acid conjugate; ergothioneine conjugate of raloxifene through in vitro and in vivo studies by Vachaspati, Prakash R., Rao, Abhijth P., Putluru, Sivaprasad, Eapen, Prasanth, Kumar, Hemantha, Landage, Raviraj, Sridhar, Srikanth, Chacko, Silvi, Bairwa, Khemraj, Sinz, Micheal, Mariappan, T. Thanga

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A Proposed Mechanism for p-Aminoclonidine Allergenicity Based on Its Relative Oxidative Lability by Thompson, Charles D, Vachaspati, Prakash R, Kolis, Stanley P, Gulden, Pamela H, Garst, Michael E, Wiese, Anne, Munk, Stephen A, Harman, W. Dean, Macdonald, Timothy L

“…p-Aminoclonidine (apraclonidine) is a selective α2 adrenergic agonist used to reduce intraocular pressure in the treatment of glaucoma. Use of apraclonidine is…”
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The synthesis and evaluation of benzannelated-azatoxins: The benzazatoxins by Miller, Thomas A., Vachaspati, Prakash R., Labroli, Marc A., Thompson, Charles D., Bulman, Amanda L., Macdonald, Timothy L.

“…The synthesis and evaluation of azatoxin congeners possessing annealed aromatic frameworks are described. The compounds were evaluated for their abilities to…”
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