Search Results - "Vacha, Jirı́"
-
1
Two MMP-2 promoter polymorphisms (-790T/G and -735C/T) in chronic heart failure
Published in Clinical chemistry and laboratory medicine (01-10-2003)“…Remodelling of extracellular matrix by activated matrix metalloproteinases is considered to contribute to progression of ventricle remodelling during chronic…”
Get more information
Journal Article -
2
Drugs elevating extracellular adenosine promote regeneration of haematopoietic progenitor cells in severely myelosuppressed mice: their comparison and joint effects with the granulocyte colony-stimulating factor
Published in European journal of haematology (01-01-2002)“…: We tested capabilities of drugs elevating extracellular adenosine and of granulocyte colony‐stimulating factor (G‐CSF) given alone or in combination to…”
Get full text
Journal Article -
3
Association of two angiotensinogen gene polymorphisms, M235T and G(–6)A, with chronic heart failure
Published in International journal of cardiology (01-06-2003)“…The aim of the study was to focus on the relationship between the angiotensinogen (AGT) gene polymorphisms, M235T and promoter G(–6)A, and chronic heart…”
Get full text
Journal Article -
4
Endothelin-1 gene polymorphism in the identification of patients at risk for malignant ventricular arrhythmia
Published in Medical science monitor (01-05-2002)“…The endothelins are peptides with vasoconstricting and growth-promoting properties. Endothelin-1 (ET-1) is known for its direct positive inotropic and…”
Get more information
Journal Article -
5
I/D ACE gene polymorphism in survival of leukemia patients – hypothesis and pilot study
Published in Medical hypotheses (01-07-2003)“…Angiotensin-I converting enzyme (ACE) is involved not only in intracellular volume regulation but also in proliferation control. Since both ACE gene…”
Get full text
Journal Article -
6
A haplotype constituted of four MMP-2 promoter polymorphisms (−1575G/A, −1306C/T, −790T/G and −735C/T) is associated with coronary triple-vessel disease
Published in Matrix biology (2004)“…Vascular lesion development is associated with an accumulation of extracellular matrix proteins within the vessel wall. The proteins are degraded by matrix…”
Get full text
Journal Article -
7
The C766T low-density lipoprotein receptor related protein polymorphism and coronary artery disease, plasma lipoproteins, and longevity in the Czech population
Published in Journal of molecular medicine (Berlin, Germany) (01-04-2001)“…Low-density lipoprotein receptor related protein (LRP) is a multifunctional endocytic receptor involved in various biological processes including the…”
Get full text
Journal Article -
8
The Relationship Among Apolipoprotein(a) Polymorphisms, the Low-Density Lipoprotein Receptor-Related Protein, and the Very Low Density Lipoprotein Receptor Genes, and Plasma Lipoprotein(A) Concentration in the Czech Population
Published in Human biology (01-02-2002)“…Increased plasma concentration of lipoprotein(a) [Lp(a)] is an established independent risk factor for coronary artery disease (CAD), which is strongly…”
Get full text
Journal Article -
9
The role of the IKAP gene polymorphisms in atopic diseases in the middle European population
Published in Journal of human genetics (01-01-2003)“…Over ten genome-wide screens and many candidate genes studies were performed worldwide to elucidate genetic factors involved in the pathogenesis of bronchial…”
Get full text
Journal Article -
10
Lack of an association of a single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene in Czech women with pregnancy-induced hypertension
Published in Gynecologic and obstetric investigation (01-01-2001)“…In preeclampsia the cytotrophoblast invasion of the decidual vessels is reduced. The endothelia in the decidual vessels may influence cytotrophoblast invasion…”
Get more information
Journal Article -
11
Duration of non-Insulin-dependent diabetes mellitus and the TNF-beta NcoI genotype as predictive factors in proliferative diabetic retinopathy
Published in Ophthalmologica (Basel) (01-07-2001)“…The object of the study was to investigate the share of the polymorphisms I/D ACE, endothelin 1 4127G/A and TNF-beta NcoI in the susceptibility to…”
Get more information
Journal Article -
12
Polymorphisms in the RAGE gene influence susceptibility to diabetes-associated microvascular dermatoses in NIDDM
Published in Journal of diabetes and its complications (01-07-2001)“…To examine genetic polymorphism in the complete sequence of the Receptor of Advanced Glycation End products (RAGE) gene and its possible associations with…”
Get full text
Journal Article -
13
C766T low-density lipoprotein receptor-related protein 1 (LRP1) gene polymorphism and susceptibility to breast cancer
Published in Breast cancer research : BCR (01-01-2003)“…Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor with an important role in regulating the activity of…”
Get full text
Journal Article -
14
Methylenetetrahydrofolate Reductase Polymorphism, Type II Diabetes Mellitus, Coronary Artery Disease, and Essential Hypertension in the Czech Population
Published in Molecular genetics and metabolism (01-06-2001)“…Increased plasma concentrations of homocysteine have been found in patients with coronary artery disease (CAD) and essential hypertension (EH) and in patients…”
Get full text
Journal Article -
15
Association of 3 gene polymorphisms with atopic diseases
Published in Journal of allergy and clinical immunology (01-04-1999)“…Background: Various peptidases, including angiotensin-converting enzyme (ACE), inactivate some inflammatory peptides that are considered to influence the…”
Get full text
Journal Article -
16
Analysis of the Interleukin‐6 Gene Promoter Polymorphisms in Czech Patients with Chronic Periodontitis
Published in Journal of periodontology (1970) (01-01-2004)“…Background: Chronic periodontitis is an inflammatory disease, which is a major cause of tooth loss. The proinflammatory cytokines interleukin‐1 (IL‐1) and…”
Get full text
Journal Article -
17
Endothelin-1 Gene Polymorphism in Patients with Malignant Arrhythmias
Published in Journal of cardiovascular pharmacology (01-11-2004)“…The endothelins are peptides with vasoconstricting and growth-promoting properties. Endothelin-1 (ET-1) is known with its direct positive inotropic and…”
Get full text
Journal Article -
18
Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population
Published in Journal of investigational allergology & clinical immunology (2002)“…Susceptibility to the development of asthma and other atopic diseases is known to be associated with genetic components. Several investigators have linked the…”
Get more information
Journal Article -
19
Genetic variation in the promoter region of the basic fibroblast growth factor gene
Published in Human immunology (01-03-2003)“…Basic fibroblast growth factor (bFGF) is a member of the fibroblast growth factor family that possess broad mitogenic and cell survival activities and is…”
Get full text
Journal Article -
20
Genetic Variations in the Human Gelatinase A (Matrix Metalloproteinase‐2) Promoter Are Not Associated With Susceptibility to, and Severity of, Chronic Periodontitis
Published in Journal of periodontology (1970) (01-07-2005)“…Background: Gelatinase A (matrix metalloproteinase‐2 [MMP‐2]) has been shown to play an important role in the pathogenesis of several disorders, including…”
Get full text
Journal Article