Search Results - "Vázquez, Jesús T."
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Features of electronic circular dichroism and tips for its use in determining absolute configuration
Published in Tetrahedron: asymmetry (15-10-2017)“…[Display omitted] This review focuses on the general features of electronic circular dichroism (ECD) as applied in determining the absolute configuration of…”
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Conformational Properties of Aryl S‑Glucosides in Solution
Published in Journal of organic chemistry (17-11-2023)“…The conformational study of saccharides and glycomimetics in solution is critical for a comprehensive understanding of their interactions with biological…”
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Absolute Configuration of Dihydro-β-agarofuran Sesquiterpenes from Maytenus jelskii and Their Potential Antitumor-Promoting Effects
Published in Journal of natural products (Washington, D.C.) (23-09-2016)“…Chemoprevention of human cancer appears to be a feasible strategy for cancer control, especially when chemopreventive intervention is involved during early…”
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4
Study of aryl triazoles for absolute configuration determination
Published in Tetrahedron: asymmetry (01-10-2016)“…[Display omitted] A variety of chiral mono- and di-1,4-disubstituted 1,2,3-triazoles were synthesized by CuAAC ‘click chemistry’ as model compounds and their…”
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Stereochemical Properties of Glucosyl Sulfoxides in Solution
Published in Journal of organic chemistry (07-10-2011)“…A series of alkyl β-glucosyl sulfoxides were synthesized and characterized in order to study their stereochemical properties. The dependence of the aglycon,…”
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Influence of the cis / trans configuration on the supramolecular aggregation of aryltriazoles
Published in Beilstein journal of organic chemistry (28-11-2019)“…The ability of - and -1,2-glucopyranosyl and cyclohexyl ditriazoles, synthesized by CuAAC "click" chemistry, to form gels was studied, their physical…”
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Iodine atoms: a new molecular feature for the design of potent transthyretin fibrillogenesis inhibitors
Published in PloS one (06-01-2009)“…The thyroid hormone and retinol transporter protein known as transthyretin (TTR) is in the origin of one of the 20 or so known amyloid diseases. TTR self…”
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Comparison of the conformational properties of carbasugars and glycosides: the role of the endocyclic oxygen
Published in Carbohydrate research (01-05-2012)“…[Display omitted] ► The rotational properties of carbasugars differ from those of glycoside analogs. ► The endocyclic oxygen is crucial for the rotational…”
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Conformational Domino Effect in Saccharides. 2. Anomeric Configuration Control
Published in Journal of organic chemistry (19-09-2008)“…A series of alkyl β-d-glucopyranosyl-(1→6)-α-d-glucopyranosides were synthesized and analyzed by NMR and CD techniques. As in their β-anomer series, the…”
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Supramolecular Helical Stacking of Metallomesogens Derived from Enantiopure and Racemic Polycatenar Oxazolines
Published in Journal of the American Chemical Society (16-04-2003)“…The present report undertakes a challenge of general interest in supramolecular chemistry: the achievement of helical organizations with controlled structure…”
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Synthetic menthyl α/β-(1→6)-diglucopyranosides-induced cell death in human leukemia cells is dependent on caspases
Published in Bioorganic & medicinal chemistry letters (01-06-2012)“…A series of alkyl α/β-(1→6)-diglucopyranosides 1−12 were synthesized and assessed for cytotoxicity against HL-60, U937, Molt-3 and MCF-7 cancer cell lines. The…”
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Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQ
Published in Organic & biomolecular chemistry (07-09-2011)“…To examine if the biological activity of the N/OFQ peptide, which is the native ligand of the pain-related and viable drug target NOP receptor, could be…”
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Conformational Domino Effect in Saccharides: A Prediction from Alkyl β-(1→6)-Diglucopyranosides
Published in Journal of organic chemistry (02-05-2008)“…A series of alkyl β-d-glucopyranosyl-(1→6)-β-d-glucopyranosides, containing nonchiral and chiral aglycons, were synthesized and analyzed by NMR and CD. The…”
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14
Antiproliferation and apoptosis induced by C-glycosides in human leukemia cancer cells
Published in Bioorganic & medicinal chemistry letters (15-08-2006)“…A large series of alkyl C-glycosides was synthesized and screened against the human promyelocytic leukemia cell line (HL60), showing significant activity and…”
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Hydroxymethyl Rotamer Populations in Disaccharides
Published in Journal of organic chemistry (13-06-2003)“…Sixteen methyl glucopyranosyl glucopyranoside disaccharides (methyl β-d-Glcp(p-Br-Bz)-(1→x)-β/α-d-Glcp) containing β-glycosidic linkages (1→2, 1→3, 1→4, and…”
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Cytotoxic effects of C-glycosides in HOS and HeLa cell lines
Published in Bioorganic & medicinal chemistry letters (01-07-2007)“…Fifty-two C-glycosides were synthesized and their in-vitro antiproliferative activity against human cervical carcinoma (HeLa) and osteosarcoma (HOS) screened,…”
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[3 + 2] Cycloaddition of Fischer Alkenyl Carbene Complexes to Enamines: An Efficient Asymmetric Approach to Cyclopentanoids
Published in Journal of the American Chemical Society (12-05-1999)Get full text
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Conformational properties of glucosyl-thioglucosides and their S-oxides in solution
Published in Tetrahedron: asymmetry (31-05-2013)“…A stereochemical study of a series of alkyl glucosyl-β-(1→6)-thioglucosides and their S-oxides by means of nuclear magnetic resonance and circular dichroism…”
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Intramolecular 1,3-dipolar cycloaddition of N-alkenyl nitrones en route to glycosyl piperidines
Published in Tetrahedron letters (23-12-2009)“…Stereoselective intramolecular 1,3-dipolar cycloaddition of homochiral N-(alkenylglycosyl)nitrones, prepared by allylation of C-(glycosyl)nitrones and…”
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Absolute configuration of glycosyl sulfoxides
Published in Tetrahedron: asymmetry (04-08-2010)“…A series of alkyl glycosyl sulfoxides were synthesized and analyzed by NMR and CD. The study of the configuration of the sulfur atom revealed several types of…”
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