Search Results - "VULTO, A. G."

Genetic Variation in the CYP2D6 Gene Is Associated With a Lower Heart Rate and Blood Pressure in β‐Blocker Users by Bijl, MJ, Visser, LE, Schaik, RHN, Kors, JA, Witteman, JCM, Hofman, A, Vulto, AG, Gelder, T, Stricker, BHCh

“…Several β‐blockers are metabolized by the polymorphic enzyme cytochrome P450 2D6 (CYP2D6). CYP2D6*4 is the main polymorphism leading to decreased enzyme…”
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The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer by Lammers, L A, Mathijssen, R H J, van Gelder, T, Bijl, M J, de Graan, A-J M, Seynaeve, C, van Fessem, M A, Berns, E M, Vulto, A G, van Schaik, R H N

“…Background: Cytochrome P450 2D6 (CYP2D6) has a crucial role in the metabolic conversion of tamoxifen into the active metabolite endoxifen. In this cohort…”
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An additional measure for quantifying antibiotic use in hospitals by Filius, P. M. G., Liem, T. B. Y., van der Linden, P. D., Janknegt, R., Natsch, S., Vulto, A. G., Verbrugh, H. A.

“…Objectives: The number of defined daily doses (DDD) per 100 patient days is often used as an indicator for the selection pressure exerted by antibiotics in the…”
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Association of graded allele-specific changes in CYP2D6 function with imipramine dose requirement in a large group of depressed patients by Schenk, P W, van Fessem, M A C, Verploegh-Van Rij, S, Mathot, R A A, van Gelder, T, Vulto, A G, van Vliet, M, Lindemans, J, Bruijn, J A, van Schaik, R H N

“…The inactivation and clearance of the tricyclic antidepressant imipramine is dependent on CYP2D6 activity. First, CYP2C19 converts imipramine into the active…”
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Recombinant human α-glucosidase from rabbit milk in Pompe patients by Van den Hout, Hannerieke, Reuser, Arnold JJ, Vulto, Arnold G, Christa B Loonen, M, Cromme-Dijkhuis, Adri, Van der Ploeg, Ans T

“…Pompe's disease is a fatal muscular disorder caused by lysosomal α-glucosidase deficiency. In an open-label study, four babies with characteristic…”
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Nicardipine in pre‐eclamptic patients: placental transfer and disposition in breast milk by Bartels, PA, Hanff, LM, Mathot, RAA, Steegers, EAP, Vulto, AG, Visser, W

“…To assess the safety risks to the fetus and neonate caused by maternal use of nicardipine in pre‐eclamptic patients, we evaluated the placental transfer and…”
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Spinal anaesthesia with articaine 5% vs bupivacaine 0.5% for day-case lower limb surgery: a double-blind randomized clinical trial by Dijkstra, T., Reesink, J.A., Verdouw, B.C., Van der Pol, W.S.C.J.M., Feberwee, T., Vulto, A.G.

“…A local anaesthetic with fast onset and short reliable duration of anaesthesia may be preferable for out-patient lower limb surgery. Articaine is believed to…”
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Review article : glycyrrhizin as a potential treatment for chronic hepatitis C by VAN RUSSUM, T. G. J, VULTO, A. G, DE MAN, R. A, BROUWER, J. T, SCHALM, S. W

“…Chronic hepatitis C is a slowly progressive liver disease that may evolve into cirrhosis with its potential complications of liver failure or hepatocellular…”
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Aerosol Delivery of Amphotericin B Desoxycholate (Fungizone) and Liposomal Amphotericin B (AmBisome): Aerosol Characteristics and In-vivo Amphotericin B Deposition in Rats by RUIJGROK, E. J., VULTO, A. G., VAN ETTEN, E. W. M.

“…In the treatment or prophylaxis of invasive pulmonary aspergillosis, it may be attractive to administer the antifungal agent amphotericin directly to the…”
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Formulating a poorly water soluble drug into an oral solution suitable for paediatric patients; lorazepam as a model drug by van der Vossen, A.C., van der Velde, I., Smeets, O.S.N.M., Postma, D.J., Eckhardt, M., Vermes, A., Koch, B.C.P., Vulto, A.G., Hanff, L.M.

“…Many drugs are unavailable in suitable oral paediatric dosage forms, and pharmacists often have to compound drugs to provide paediatric patients with an…”
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Intravenous glycyrrhizin for the treatment of chronic hepatitis C: A double-blind, randomized, placebo-controlled phase I/II trial by Rossum, Tekla Gj Van, Vulto, Arnold G, Hop, Wim Cj, Brouwer, Johannes T, Niesters, Hubert Gm, Schalm, Solko W

“…Background : In Japan, glycyrrhizin therapy is widely used for chronic hepatitis C and reportedly reduces the progression of liver disease to hepatocellular…”
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Unapproved and Off-Label Use of Drugs in a Children's Hospital by `t Jong, Geert W, Vulto, Arnold G, de Hoog, Matthijs, Schimmel, Kirsten J.M, Tibboel, Dick, van den Anker, John N

“…To the Editor: Treatment of children may be difficult because of a shortage of properly formulated or approved drugs. 1 In the Netherlands and elsewhere, many…”
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Design and stability study of an oral solution of amlodipine besylate for pediatric patients by van der Vossen, A.C., van der Velde, I., Smeets, O.S.N.M., Postma, D.J., Vermes, A., Koch, B.C.P., Vulto, A.G., Hanff, L.M.

“…Amlodipine is an antihypertensive agent recommended for the management of hypertension in children and adolescents. The commercially available tablets of 5 and…”
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Comparative evaluation of three chromogenic agars for detection and rapid identification of aerobic Gram-negative bacteria in the normal intestinal microflora by Filius, P.M.G., van Netten, D., Roovers, P.J.E., Vulto, A.G., Gyssens, I.C., Verbrugh, H.A., Endtz, H.P.

“…To compare three different chromogenic agars and MacConkey agar for the detection of aerobic Gram-negative bacteria in the normal intestinal microflora and to…”
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Ketanserin in pre‐eclamptic patients: transplacental transmission and disposition in neonates by Hanff, L.M., Visser, W., Roofthooft, D.W.E., Bulsink, M.J.E., Vermes, A., Steegers, E.A.P., Vulto, A.G.

“…The aim of this prospective, observational study was to assess transplacental transmission of ketanserin, an antihypertensive drug used in pre‐eclampsia, and…”
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Intoxication with therapeutic and illicit drug substances and hospital admission to a Dutch University Hospital by VERMES, A, ROELOFSEN, E. E, SABADI, G, VAN DEN BERG, B, DE QUELERIJ, M, VULTO, A. G

“…This article describes the retrospective analysis of the patients who presented with a drug-related intoxication to the emergency department of the Erasmus…”
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Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection by van Rossum, Tekla G.J., Vulto, Arnold G., Hop, Wim C.J., Schalm, Solko W.

“…Intravenous glycyrrhizin has been used in Japan for the treatment of chronic hepatitis for >20 years, although only a few reports of its pharmacokinetic…”
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Understanding HIV infection for the design of a therapeutic vaccine. Part I: Epidemiology and pathogenesis of HIV infection by de Goede, A L, Vulto, A G, Osterhaus, A D M E, Gruters, R A

“…HIV infection leads to a gradual loss CD4+ T lymphocytes comprising immune competence and progression to AIDS. Effective treatment with combined antiretroviral…”
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Pharmacokinetics of the Protease Inhibitor Indinavir in Human Immunodeficiency Virus Type 1-Infected Children by BURGER, David M, VAN ROSSUM, Annemarie M. C, HUGEN, Patricia W. H, SUUR, Marja H, HARTWIG, Nico G, GEELEN, Sibyl P. M, SCHERPBIER, Henriette J, HOETELMANS, Richard M. W, VULTO, Arnold G, DE GROOT, Ronald

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Changes in antibiotic use in Dutch hospitals over a six-year period: 1997 to 2002 by Liem, T B Y, Filius, F M G, van der Linden, P D, Janknegt, R, Natsch, S, Vulto, A G

“…To analyse trends in antibiotic use in Dutch hospitals over the period 1997 to 2002. Data on the use of antibiotics and hospital resource indicators were…”
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