Search Results - "VRANIZAN, Karen"
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GO-Elite: a flexible solution for pathway and ontology over-representation
Published in Bioinformatics (15-08-2012)“…We introduce GO-Elite, a flexible and powerful pathway analysis tool for a wide array of species, identifiers (IDs), pathways, ontologies and gene sets. In…”
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GenMAPP 2: new features and resources for pathway analysis
Published in BMC bioinformatics (24-06-2007)“…Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence…”
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p63 Regulates Olfactory Stem Cell Self-Renewal and Differentiation
Published in Neuron (Cambridge, Mass.) (08-12-2011)“…The olfactory epithelium is a sensory neuroepithelium that supports adult neurogenesis and tissue regeneration following injury, making it an excellent model…”
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Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-2010)“…Two major goals of regenerative medicine are to reproducibly transform adult somatic cells into a pluripotent state and to control their differentiation into…”
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GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
Published in Nature genetics (01-05-2002)Get full text
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An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol
Published in PloS one (22-07-2011)“…Anaplastic lymphoma kinase (Alk) is a gene expressed in the nervous system that encodes a receptor tyrosine kinase commonly known for its oncogenic function in…”
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Developmental and evolutionary basis for drought tolerance of the Anopheles gambiae embryo
Published in Developmental biology (15-06-2009)“…During the evolution of the Diptera there is a dramatic modification of the embryonic ectoderm, whereby mosquitoes contain separate amnion and serosa lineages…”
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Time- and exercise-dependent gene regulation in human skeletal muscle
Published in Genome biology (01-01-2003)“…Skeletal muscle remodeling is a critical component of an organism's response to environmental changes. Exercise causes structural changes in muscle and can…”
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Alternative splicing in the differentiation of human embryonic stem cells into cardiac precursors
Published in PLoS computational biology (01-11-2009)“…The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of human embryonic stem cells (hESCs) is largely unknown. To…”
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Temporal gene expression profiling during rat femoral marrow ablation-induced intramembranous bone regeneration
Published in PloS one (01-10-2010)“…Enhanced understanding of differential gene expression and biological pathways associated with distinct phases of intramembranous bone regeneration following…”
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Gene Expression Patterns Define Key Transcriptional Events in Cell-Cycle Regulation by cAMP and Protein Kinase A
Published in Proceedings of the National Academy of Sciences - PNAS (14-06-2005)“…Although a substantial number of hormones and drugs increase cellular cAMP levels, the global impact of cAMP and its major effector mechanism, protein kinase A…”
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Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation
Published in Proceedings of the National Academy of Sciences - PNAS (15-05-2007)“…Sudden cardiac death due to abnormal heart rhythm kills 400,000-460,000 Americans each year. To identify genes that regulate heart rhythm, we are developing a…”
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Analysis of gene expression during neurite outgrowth and regeneration
Published in BMC neuroscience (23-11-2007)“…The ability of a neuron to regenerate functional connections after injury is influenced by both its intrinsic state and also by extrinsic cues in its…”
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Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling
Published in Molecular and cellular neuroscience (01-02-2011)“…The local progenitor population in the olfactory bulb (OB) gives rise to mitral and tufted projection neurons during embryonic development. In contrast, OB…”
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The Fall and Rise of Carotid Endarterectomy in the United States and Canada
Published in The New England journal of medicine (12-11-1998)“…Since its introduction in 1954, carotid endarterectomy for the prevention of stroke has been controversial. 1 Rates of carotid endarterectomy rose until the…”
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Conditional Expression of a Gi-Coupled Receptor Causes Ventricular Conduction Delay and a Lethal Cardiomyopathy
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2000)“…Cardiomyopathy is a major cause of morbidity and mortality. Ventricular conduction delay, as shown by prolonged deflections in the electrocardiogram caused by…”
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Gene Expression Signatures of cAMP/Protein Kinase A (PKA)-promoted, Mitochondrial-dependent Apoptosis
Published in The Journal of biological chemistry (15-02-2008)“…The second messenger cAMP acts via protein kinase A (PKA) to induce apoptosis by mechanisms that are poorly understood. Here, we assessed a role for…”
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Modeling insertional mutagenesis using gene length and expression in murine embryonic stem cells
Published in PloS one (18-07-2007)“…High-throughput mutagenesis of the mammalian genome is a powerful means to facilitate analysis of gene function. Gene trapping in embryonic stem cells (ESCs)…”
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Changes in plasma lipids and lipoproteins in overweight men during weight loss through dieting as compared with exercise
Published in The New England journal of medicine (03-11-1988)“…We studied separately the influence of two methods for losing fat weight on the levels of plasma lipids and lipoproteins in overweight sedentary…”
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Who uses needle exchange? A study of injection drug users in treatment in San Francisco, 1989-1990
Published in Journal of acquired immune deficiency syndromes and human retrovirology (01-06-1997)“…We examined use of the San Francisco needle exchange program (NEP) by 1093 injection drug users (IDUs) recruited in methadone maintenance and out-patient…”
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