Search Results - "VOTH, E"

Clostridium difficile Toxins: Mechanism of Action and Role in Disease by VOTH, Daniel E, BALLARD, Jimmy D

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Take my breath away: studying pathogen invasion of the human lung using primary tissue models by Dragan, Amanda L, Voth, Daniel E

“…ABSTRACT The human pulmonary environment is complex, containing a matrix of cells, including fibroblasts, epithelial cells, interstitial macrophages, alveolar…”
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Lounging in a lysosome: the intracellular lifestyle of Coxiella burnetii by Voth, Daniel E, Heinzen, Robert A

“…Most intracellular parasites employ sophisticated mechanisms to direct biogenesis of a vacuolar replicative niche that circumvents default maturation through…”
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Hijacking Host Cell Highways: Manipulation of the Host Actin Cytoskeleton by Obligate Intracellular Bacterial Pathogens by Colonne, Punsiri M, Winchell, Caylin G, Voth, Daniel E

“…Intracellular bacterial pathogens replicate within eukaryotic cells and display unique adaptations that support key infection events including invasion,…”
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Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes by Winchell, Caylin G, Graham, Joseph G, Kurten, Richard C, Voth, Daniel E

“…Coxiella burnetii is an intracellular Gram-negative bacterium that causes human Q fever, a flu-like disease that can progress to chronic, life-threatening…”
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Development and validation of systems for genetic manipulation of the Old World tick-borne relapsing fever spirochete, Borrelia duttonii by Jackson-Litteken, Clay D, Guo, Wanfeng, Hogland, Brandon A, Ratliff, C Tyler, McFadden, LeAnn, Fullerton, Marissa S, Voth, Daniel E, Rego, Ryan O M, Blevins, Jon S

“…Relapsing fever (RF), a vector-borne disease caused by Borrelia spp., is characterized by recurring febrile episodes due to repeated bouts of bacteremia. RF…”
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The Coxiella burnetii Cryptic Plasmid Is Enriched in Genes Encoding Type IV Secretion System Substrates by VOTH, Daniel E, BEARE, Paul A, HOWE, Dale, SHARMA, Uma M, SAMOILIS, Georgios, COCKRELL, Diane C, OMSLAND, Anders, HEINZEN, Robert A

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Sustained Activation of Akt and Erk1/2 Is Required for Coxiella burnetii Antiapoptotic Activity by Voth, Daniel E, Heinzen, Robert A

“…Coxiella burnetii is an obligate intracellular bacterial pathogen that directs biogenesis of a lysosome-like, parasitophorous vacuole in mammalian cells. We…”
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X-ray Irradiation Reduces Live Aspergillus flavus Viability but Not Aflatoxin B1 in Naturally Contaminated Maize by Glesener, Hannah, Abdollahzadeh, Darya, Muse, Christopher, Krajmalnik-Brown, Rosa, Weaver, Mark A, Voth-Gaeddert, Lee E

“…Food crops around the world are commonly contaminated with , which can produce the carcinogenic mycotoxin aflatoxin B1 (AFB1). The objective of this study is…”
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Editorial: Obligate intracellular bacteria: Evasion and adaptative tactics shaping the host-pathogen interface by Simões, Isaura, Voth, Daniel E., Mota, Luís Jaime

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Dot/Icm type IVB secretion system requirements for Coxiella burnetii growth in human macrophages by Beare, Paul A, Gilk, Stacey D, Larson, Charles L, Hill, Joshua, Stead, Christopher M, Omsland, Anders, Cockrell, Diane C, Howe, Dale, Voth, Daniel E, Heinzen, Robert A

“…Central to Q fever pathogenesis is replication of the causative agent, Coxiella burnetii, within a phagolysosome-like parasitophorous vacuole (PV) in…”
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Breathe In, Breathe Out: Metabolic Regulation of Lung Macrophages in Host Defense Against Bacterial Infection by Andrews, J. Tucker, Voth, Daniel E., Huang, Stanley Ching-Cheng, Huang, Lu

“…Lung macrophages are substantially distinct from other tissue-resident macrophages. They act as frontier sentinels of the alveolar-blood interface and are…”
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Refining the Plasmid-Encoded Type IV Secretion System Substrate Repertoire of Coxiella burnetii by Maturana, Pauline, Graham, Joseph G, Sharma, Uma M, Voth, Daniel E

“…The intracellular bacterial agent of Q fever, Coxiella burnetii, translocates effector proteins into its host cell cytosol via a Dot/Icm type IV secretion…”
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Coxiella burnetii Inhibits Apoptosis in Human THP-1 Cells and Monkey Primary Alveolar Macrophages by Voth, Daniel E, Howe, Dale, Heinzen, Robert A

“…Coxiella burnetii, the cause of human Q fever, is an aerosol-borne, obligate intracellular bacterium that targets host alveolar mononuclear phagocytic cells…”
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The Coxiella burnetii Ankyrin Repeat Domain-Containing Protein Family Is Heterogeneous, with C-Terminal Truncations That Influence Dot/Icm-Mediated Secretion by VOTH, Daniel E, HOWE, Dale, BEARE, Paul A, VOGEL, Joseph P, UNSWORTH, Nathan, SAMUEL, James E, HEINZEN, Robert A

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Evaluating the costs and components of a territory-wide household water storage and treatment program in the US Virgin Islands by Voth-Gaeddert, Lee E., Momberg, Douglas, Brathwaite, Kela, Schranck, Andrew, Libbey, Stephen, Lemley, Mandy

“…Abstract Among island communities, water security and access continue to be a critical issue. In the US Virgin Islands (USVI), 90% of households are capable of…”
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Comparative Genomics Reveal Extensive Transposon-Mediated Genomic Plasticity and Diversity among Potential Effector Proteins within the Genus Coxiella by Beare, Paul A, Unsworth, Nathan, Andoh, Masako, Voth, Daniel E, Omsland, Anders, Gilk, Stacey D, Williams, Kelly P, Sobral, Bruno W, Kupko, John J. III, Porcella, Stephen F, Samuel, James E, Heinzen, Robert A

“…Genetically distinct isolates of Coxiella burnetii, the cause of human Q fever, display different phenotypes with respect to in vitro infectivity/cytopathology…”
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Identification of Clostridium difficile Toxin B Cardiotoxicity Using a Zebrafish Embryo Model of Intoxication by Hamm, Elaine E., Voth, Daniel E., Ballard, Jimmy D.

“…Clostridium difficile toxin B (TcdB) has been studied extensively by using cell-free systems and tissue culture, but, like many bacterial toxins, the in vivo…”
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Coxiella burnetii Alters Cyclic AMP-Dependent Protein Kinase Signaling during Growth in Macrophages by MACDONALD, Laura J, KURTEN, Richard C, VOTH, Daniel E

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Identification of Anaplasma marginale type IV secretion system effector proteins by Lockwood, Svetlana, Voth, Daniel E, Brayton, Kelly A, Beare, Paul A, Brown, Wendy C, Heinzen, Robert A, Broschat, Shira L

“…Anaplasma marginale, an obligate intracellular alphaproteobacterium in the order Rickettsiales, is a tick-borne pathogen and the leading cause of anaplasmosis…”
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