Search Results - "VOSTAL, Jaroslav G"

P38 mitogen activated protein kinase inhibitor improves platelet in vitro parameters and in vivo survival in a SCID mouse model of transfusion for platelets stored at cold or temperature cycled conditions for 14 days by Skripchenko, Andrey, Gelderman, Monique P, Vostal, Jaroslav G

“…Platelets for transfusion are stored at room temperature (20-24°C) up to 7 days but decline in biochemical and morphological parameters during storage and can…”
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Temperature cycling during platelet cold storage improves in vivo recovery and survival in healthy volunteers by Vostal, Jaroslav G., Gelderman, Monique P., Skripchenko, Andrey, Xu, Fei, Li, Ying, Ryan, Johannah, Cheng, Chunrong, Whitley, Pam, Wellington, Michael, Sawyer, Sherrie, Hanley, Shalene, Wagner, Stephen J.

“…BACKGROUND Room temperature (RT) storage of platelets (PLTs) can support bacterial proliferation in contaminated units, which can lead to…”
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Validation of a SCID mouse model for transfusion by concurrent comparison of circulation kinetics of human platelets, stored under various temperature conditions, between human volunteers and mice by Gelderman, Monique P., Cheng, Chunrong, Xu, Fei, Skripchenko, Andrey, Ryan, Johannah, Li, Ying, Whitley, Pamela, Wagner, Stephen J., Vostal, Jaroslav G.

“…Background Initial evaluation of new platelet (PLT) products for transfusion includes a clinical study to determine in vivo recovery and survival of autologous…”
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Automated cold temperature cycling improves in vitro platelet properties and in vivo recovery in a mouse model compared to continuous cold storage by Skripchenko, Andrey, Gelderman, Monique P., Awatefe, Helen, Turgeon, Annette, Thompson-Montgomery, Dedeene, Cheng, Chunrong, Vostal, Jaroslav G., Wagner, Stephen J.

“…BACKGROUND Platelets (PLTs) stored at cold temperatures (CTs) for prolonged time have dramatically reduced bacterial growth but poor survival when infused. A…”
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Macrophage Depletion Mitigates Platelet Aggregate Formation in Splenic Marginal Zone and Alleviates LPS-Associated Thrombocytopenia in Rats by Li, Ying, Ryan, Johannah, Xu, Fei, Vostal, Jaroslav G

“…Sepsis is often accompanied with thrombocytopenia partly due to platelet sequestration in the lung and liver. The spleen can store up to one-third of…”
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In vitro and in vivo characterization of ultraviolet light C-irradiated human platelets in a 2 event mouse model of transfusion by Zhi, Li, Chi, Xuan, Vostal, Jaroslav G

“…UV-based pathogen reduction technologies have been developed in recent years to inactivate pathogens and contaminating leukocytes in platelet transfusion…”
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Evaluation of Stem Cell-Derived Red Blood Cells as a Transfusion Product Using a Novel Animal Model by Shah, Sandeep N, Gelderman, Monique P, Lewis, Emily M A, Farrel, John, Wood, Francine, Strader, Michael Brad, Alayash, Abdu I, Vostal, Jaroslav G

“…Reliance on volunteer blood donors can lead to transfusion product shortages, and current liquid storage of red blood cells (RBCs) is associated with…”
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Expression of the cellular prion protein affects posttransfusion recovery and survival of red blood cells in mice by Glier, Hana, Simak, Jan, Panigaj, Martin, Gelderman, Monique P., Vostal, Jaroslav G., Holada, Karel

“…BACKGROUND Cellular prion protein (PrPC) is expressed on various cell types including red blood cells (RBCs). The PrPC plays a key role in the pathogenesis of…”
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Rejuvenation improves roller pump-induced physical stress resistance of fresh and stored red blood cells by Gelderman, Monique P., Vostal, Jaroslav G.

“…BACKGROUND: Retrospective studies on transfusion recipients suggested that transfusion of older red blood cells (RBCs) was associated with higher morbidity…”
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Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury by Chi, Xuan, Zhi, Li, Gelderman, Monique P, Vostal, Jaroslav G

“…We previously reported that ultraviolet light B (UVB)-treated human platelets (hPLTs) can cause acute lung injury (ALI) in a two-event SCID mouse model in…”
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Underestimation of the expression of cellular prion protein on human red blood cells by Panigaj, Martin, Brouckova, Adela, Glierova, Hana, Dvorakova, Eva, Simak, Jan, Vostal, Jaroslav G., Holada, Karel

“…BACKGROUND: Recent transmissions of variant Creutzfeldt‐Jakob disease by blood transfusion emphasize the need for the development of prion screening tests. The…”
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Elevated circulating endothelial membrane microparticles in paroxysmal nocturnal haemoglobinuria by Simak, Jan, Holada, Karel, Risitano, Antonio M., Zivny, Jan H., Young, Neal S., Vostal, Jaroslav G.

“…Summary We analysed endothelial cell membrane microparticles (ECMP) in the peripheral blood of patients with paroxysmal nocturnal haemoglobinuria (PNH) (n =…”
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Divergent expression of cellular prion protein on blood cells of human and nonhuman primates by Holada, Karel, Simak, Jan, Brown, Paul, Vostal, Jaroslav G.

“…BACKGROUND: Four recent transmissions of variant Creutzfeldt‐Jakob disease infection by transfusion highlight the need for detailed understanding of…”
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Scrapie Infectivity in Hamster Blood Is Not Associated with Platelets by Holada, Karel, Vostal, Jaroslav G, Theisen, Patrick W, MacAuley, Claudia, Gregori, Luisa, Rohwer, Robert G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Inactivation of bacteria via photosensitization of vitamin K3 by UV-A light by Xu, Fei, Vostal, Jaroslav G.

“…Abstract This study investigated inactivation of bacteria with ultraviolet light A irradiation in combination with vitamin K3 as a photosensitizer. Six…”
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Viral reduction of human blood by ultraviolet A‐photosensitized vitamin K5 by He, Yong, Xu, Fei, Ibrahim, Zina, Feyissa, Qinati, Reed, Jennifer L., Vostal, Jaroslav G.

“…Blood product transfusion can transmit viral pathogens. Pathogen reduction methods for blood products have been developed but, so far, are not available for…”
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In vivo recovery of human platelets in severe combined immunodeficient mice as a measure of platelet damage by Piper, John T., Gelderman, Monique P., Vostal, Jaroslav G.

“…BACKGROUND: Clinical performance of human platelet (PLT) products processed or stored under novel conditions is difficult to predict based on in vitro studies…”
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Synergistic bactericidal effects of pairs of photosensitizer molecules activated by ultraviolet A light against bacteria in plasma by Feyissa, Qinati, Xu, Fei, Ibrahim, Zina, Li, Ying, Xu, Kevin L., Guo, Zihan, Ahmad, Justen, Vostal, Jaroslav G.

“…Background The current approach to reducing bacterial contamination in blood transfusion products is through detection or pathogen reduction methods, some of…”
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Current and Future Cellular Transfusion Products by Gelderman, Monique P., PhD, Vostal, Jaroslav G., MD, PhD

“…Novel red blood cell and platelet transfusion products may be synthetic or may result from modifications to approved collection, processing, and storage…”
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Vitamin K5 is an efficient photosensitizer for ultraviolet A light inactivation of bacteria by Xu, Fei, Li, Ying, Ahmad, Justen, Wang, Yonggang, Scott, Dorothy E, Vostal, Jaroslav G

“…Abstract Photodynamic treatment combining light and a photosensitizer molecule can be an effective method to inactivate pathogenic bacteria. This study…”
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