Search Results - "VORHERR, T"

The aspartimide problem in Fmoc-based SPPS. Part I by Mergler, M., Dick, F., Sax, B., Weiler, P., Vorherr, T.

“…A variety of Asp β‐carboxy protecting groups, Hmb backbone protection and a range of Fmoc cleavage protocols have been employed in syntheses of the model…”
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The aspartimide problem in Fmoc-based SPPS. Part II by Mergler, M., Dick, F., Sax, B., Stähelin, C., Vorherr, T.

“…The sequence dependence of base‐catalysed aspartimide formation during Fmoc‐based SPPS was systematically studied employing the peptide models…”
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The plasma membrane Ca2+ pump contains a site that interacts with its calmodulin-binding domain by FALCHETTO, R, VORHERR, T, BRUNNER, J, CARAFOLI, E

“…A synthetic, 28-residue peptide derived from the calmodulin-binding sequence of the plasma membrane Ca2+ pump (C28W) inhibits the ATPase activity of a…”
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Phosphorylation of the calmodulin binding domain of the plasma membrane Ca2+ pump by protein kinase C reduces its interaction with calmodulin and with its pump receptor site by Hofmann, F, Anagli, J, Carafoli, E, Vorherr, T

“…Two versions of the calmodulin binding domain of the plasma membrane Ca2+ ATPase, a 24-amino acid peptide, C24W…”
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The calmodulin-binding domain mediates the self-association of the plasma membrane Ca2+ pump by Vorherr, T, Kessler, T, Hofmann, F, Carafoli, E

“…Dimerization (oligomerization) of the plasma membrane Ca2+ pump increases its activity (Kosk-Kosicka, D., Bzdega, T., and Wawrzynow, A. (1989) J. Biol. Chem…”
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Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane by STREHLER, E. E, JAMES, P, FISCHER, R, HEIM, R, VORHERR, T, FILOTEO, A. G, PENNISTON, J. T, CARAFOLI, E

“…The sequence of more than 1,000 amino acid residues, derived from two different isoforms, has been determined from peptides generated from purified human…”
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Synthesis and Application of Fmoc-His(3-Bum)-OH by Mergler, M., Dick, F., Sax, B., Schwindling, J., Vorherr, Th

“…This paper presents a reevaluation of the synthesis and properties of Fmoc‐His(3‐Bum)‐OH regarding its application in SPPS with minimal racemization of…”
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Global phosphorylation of peptides containing oxidation-sensitive amino acids by Bannwarth, W., Küng, E., Vorherr, T.

“…We report on an extension of the global phosphorylation procedure for the preparation of phosphopeptides containing oxidation-sensitive amino acids such as…”
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Total synthesis and functional properties of the membrane‐intrinsic protein phospholamban by Vorherr, Thomas, Carafoli, Ernesto, Wrzosek, Antoni, Chiesi, Michele

“…The membrane‐intrinsic protein phospholamban (PLN), the regulatory protein of the sarcoplasmic reticulum (SR) Ca2+‐ATPase, was chemically synthesized. The…”
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Peptide thioester preparation based on an N- S acyl shift reaction mediated by a thiol ligation auxiliary by Kawakami, Toru, Sumida, Megumi, Nakamura, Ken’ichiroh, Vorherr, Thomas, Aimoto, Saburo

“…Formation of peptide thioesters, based on an N to S acyl shift mediated by an auxiliary, N-4,5-dimethoxy-2-mercaptobenzyl (Dmmb) group, under acidic…”
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The Secondary Structure of Phospholamban: A Two-Dimensional NMR Study by Maslennikov, I.V., Sobol, A.G., Anagli, J., James, P., Vorherr, T., Arseniev, A.S., Carafoli, E.

“…Phospholamban (PLN) is an intrinsic membrane protein of 52 amino acids which regulates the Ca2+ pump of the sarcoplasmic reticulum of heart, slow-twitch and…”
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The C-terminal domain of the plasma membrane Ca2+ pump contains three high affinity Ca2+ binding sites by Hofmann, F., James, P., Vorherr, T., Carafoli, E.

“…The C-terminal portion of the plasma membrane Ca(2+)-ATPase contains different regulatory domains. A recombinant C-terminal fragment of the human plasma…”
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Calmodulin-binding domains: just two faced or multi-faceted? by James, Peter, Vorherr, Thomas, Carafoli, Ernesto

“…The Ca 2+-binding protein calmodulin binds to and activates several cellular enzymes in response to a rise in Ca 2+ concentration. It binds certain basic…”
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Primary structure of the cAMP-dependent phosphorylation site of the plasma membrane calcium pump by James, Peter H, Pruschy, Martin, Vorherr, Thomas E, Penniston, John T, Carafoli, Ernesto

“…The primary structure of a region of the erythrocyte plasma membrane calcium pump which is phosphorylated by the cAMP-dependent protein kinase has been…”
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The calmodulin‐binding site of the plasma membrane Ca2+ pump interacts with the transduction domain of the enzyme by Falchetto, Rocco, Vorherr, Thomas, Carafoli, Ernesto

“…Calpain proteolysis of the plasma membrane Ca2+ pump removes a C‐terminal 14‐kDa portion which includes the calmodulin‐binding domain. This produces a fully…”
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A monoclonal antibody recognizes an epitope in the first extracellular loop of the plasma membrane Ca2+ pump by Feschenko, M S, Zvaritch, E I, Hofmann, F, Shakhparonov, M I, Modyanov, N N, Vorherr, T, Carafoli, E

“…A monoclonal antibody against the human erythrocyte Ca2+ pump (1E4) reacted with the enzyme in intact erythrocytes. Using trypsinized preparations of the pump…”
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Generation of an S-Peptide via an N–S Acyl Shift Reaction in a TFA Solution by Nakamura, Ken’ichiroh, Sumida, Megumi, Kawakami, Toru, Vorherr, Thomas, Aimoto, Saburo

“…An N–S acyl shift reaction of thiol-containing peptides in a trifluoroacetic acid (TFA) solution was confirmed by a combination of 13C NMR spectroscopy,…”
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Anti-CD3 and phorbol ester induce distinct phosphorylated sites in the SH2 domain of p56lck by Soula, M, Rothhut, B, Camoin, L, Guillaume, J L, Strosberg, D, Vorherr, T, Burn, P, Meggio, F, Fischer, S, Fagard, R

“…P56lck is a protein tyrosine kinase of the Src family specifically expressed in T lymphocytes. Triggering of T cells with anti-CD3 or with phorbol 12-myristate…”
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NMR Solution Structure of a Complex of Calmodulin with a Binding Peptide of the Ca2+ Pump by Elshorst, Bettina, Hennig, Mirko, Försterling, Holger, Diener, Alexander, Maurer, Marcus, Schulte, Petra, Schwalbe, Harald, Griesinger, Christian, Krebs, Joachim, Schmid, Holger, Vorherr, Thomas, Carafoli, Ernesto

“…The three-dimensional structure of the complex between calmodulin (CaM) and a peptide corresponding to the N-terminal portion of the CaM-binding domain of the…”
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H+-induced Membrane Insertion of Influenza Virus Hemagglutinin Involves the HA2 Amino-terminal Fusion Peptide but Not the Coiled Coil Region by Durrer, Peter, Galli, Carmela, Hoenke, Stefan, Corti, Chantal, Glück, Reinhard, Vorherr, Thomas, Brunner, Josef

“…Fusion of influenza virus with target membranes is induced by acid and involves complex changes in the viral envelope protein hemagglutinin (HA). In a first,…”
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